N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
- Product Name
- N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
- CAS No.
- 218796-15-7
- Chemical Name
- N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
- Synonyms
- Reaxys ID: 22644225;N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide;N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE;Acetamide, N-(2-chloro-6-fluoro-3-nitrophenyl)-
- CBNumber
- CB7745049
- Molecular Formula
- C8H6ClFN2O3
- Formula Weight
- 232.6
- MOL File
- Mol file
N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Property
- Boiling point:
- 375.2±42.0 °C(Predicted)
- Density
- 1.545±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 12.19±0.70(Predicted)
- Appearance
- Off-white to brown Solid
Safety
- HS Code
- 2924297099
N-Bromosuccinimide Price
- Product number
- 084877
- Product name
- N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
- Purity
- 97%
- Packaging
- 1g
- Price
- $561
- Updated
- 2021/12/16
- Product number
- 7439AD
- Product name
- N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
- Packaging
- 1g
- Price
- $590
- Updated
- 2021/12/16
- Product number
- HCH0008295
- Product name
- N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $892.53
- Updated
- 2021/12/16
- Product number
- 4654-3-2K
- Product name
- N1-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
- Purity
- 95.0%
- Packaging
- 250mg
- Price
- $255
- Updated
- 2021/12/16
- Product number
- CD12095540
- Product name
- N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $396
- Updated
- 2021/12/16
N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Chemical Properties,Usage,Production
Synthesis
343-73-7
218796-15-7
Step 2: Preparation of N-(2-chloro-6-fluoro-3-nitrophenyl)acetamide. Sodium nitrate (4.53 g, 53.3 mmol) was dissolved in water (5 mL) and slowly added dropwise to a stirred solution of N-(2-chloro-6-fluorophenyl)acetamide (5 g, 26.7 mmol) in concentrated sulfuric acid (10 mL). After dropwise addition, the resulting yellow solution was stirred at 0 °C for 30 min, then warmed up to room temperature and continued stirring for 12 hours. Upon completion of the reaction, the mixture was poured into water (~250 mL) and the precipitated solid was collected by vacuum filtration. The crude product was purified by recrystallization from acetonitrile to give the title compound in the form of a light brown solid (3.2 g, 49% yield). The product was characterized as follows: 1H NMR (400 MHz, DMSO-d6) δ 10.07 (s, 1H), 8.12 (dd, J = 9.2, 5.0 Hz, 1H), 7.70-7.55 (m, 1H), 2.12 (s, 3H); ESIMS m/z 233 ([M + H]+).
References
[1] Patent: US2018/98541, 2018, A1. Location in patent: Paragraph 1669
[2] Patent: WO2012/85127, 2012, A1. Location in patent: Page/Page column 40
[3] Patent: US2012/322803, 2012, A1. Location in patent: Page/Page column 18
N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Suppliers
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