ChemicalBook > CAS DataBase List > 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

Product Name
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
CAS No.
149676-40-4
Chemical Name
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
Synonyms
EU-5306;RB-1589;PERFLOXACINE;PEFLOXACIN METHANESULFONATE;Pefloxacin Mesylate dihydra;PEFLOXACIN MESYLATE DIHYDRATE;Pefloxacin (mesylate hydrate);PEFLOXACINE MESYLATE DIHYDRATE;Pefloxacin mesylate dihydrdate;Pefloxacin dihydrate mesylate
CBNumber
CB7748671
Molecular Formula
C18H28FN3O8S
Formula Weight
465.49
MOL File
149676-40-4.mol
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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Property

Melting point:
271°C
Boiling point:
529℃
Flash point:
>110°(230°F)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
Water Solubility 
Freely soluble in water
Sensitive 
Light Sensitive
CAS DataBase Reference
149676-40-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
RTECS 
VB2002200
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P0309000
Product name
Pefloxacin mesilate dihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
p0309000
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
P0106
Product name
Pefloxacin mesylate dihydrate
Packaging
10g
Price
$74.1
Updated
2024/03/01
Alfa Aesar
Product number
J66285
Product name
Pefloxacine methanesulfonate dihydrate, 95%
Packaging
10g
Price
$42.1
Updated
2023/06/20
Alfa Aesar
Product number
J66285
Product name
Pefloxacine methanesulfonate dihydrate, 95%
Packaging
50g
Price
$134
Updated
2021/12/16
Cayman Chemical
Product number
29103
Product name
Pefloxacin (mesylate hydrate)
Packaging
10g
Price
$37
Updated
2024/03/01
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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

antifungal, calmodulin antagonist

Uses

Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase.

Biological Activity

Pefloxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited . Pefloxacin is an analog of norfloxacin.

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Suppliers

Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
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Syntechem Co.,Ltd
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Fax
E-Mail Inquiry
Email
info@syntechem.com
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China
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
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China
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Beijing HuaMeiHuLiBiological Chemical
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010-56205725
Fax
010-65763397
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waley188@sohu.com
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China
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12335
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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+86 21 50676805
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China
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9ding chemical ( Shanghai) Limited
Tel
4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
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The future of Shanghai Industrial Co., Ltd.
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021-61552785
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021-55660885
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sales@shshiji.com
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China
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MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
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Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
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isunpharm@qq.com
Country
China
ProdList
4674
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View Lastest Price from 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID manufacturers

Dideu Industries Group Limited
Product
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID 149676-40-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-19
Career Henan Chemical Co
Product
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID 149676-40-4
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

149676-40-4, 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACIDRelated Search:


  • RB-1589
  • PERFLOXACINE
  • PEFLOXACINE MESYLATE DIHYDRATE
  • PEFLOXACINE METHANSULFONATE DIHYDRATE
  • PEFLOXACIN MESYLATE DIHYDRATE
  • PEFLOXACIN METHANESULFONATE
  • PEFLOXACIN METHANE SULFONATE DIHYDRATE
  • EU-5306
  • Pefloxacinium mesylate dihydrate
  • 1-ETHYL-6-FLUORO-1,4-DIHYDRO-7-(4-METHYL-1-PIPERAZINYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID) METHANE SULPHONATE DIHYDRATE
  • Pefloxacin dihydrate mesylate
  • Pefloxacine monomethanesulfonate dihydrate, Pefloxacinium methanesulfonate dihydrate, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate
  • /1-ethyl-6-fluoro-7-(4-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid coMpound with Methanesulfonic acid (1:1
  • 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-Methyl-1-piperazinyl)-4-oxo-, Methanesulfonate, hydrate (1:1:2)
  • Pefloxacin Mesylate dihydra
  • 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate
  • Pefloxacine monomethanesulfonate dihydrate
  • Pefloxacinium methanesulfonate dihydrate
  • Pefloxacin mesylate`Pefloxacin mesylate dihydrate
  • 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID USP/EP/BP
  • 1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid mesylate dihydrate
  • Pefloxacin mesylate dihydrdate
  • Pefloxacin dihydrate methanesulfonate
  • 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-Quinolinecarboxylic acid methanesulfonate hydrate (1:1:2)
  • Pefloxacin (mesylate hydrate)
  • /1-Ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinolin-3-carboxylic acid compound with methanesulfonic acid (1:1
  • 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound with methanesulfonic acid (1:1) hydrate
  • Pefloxacin Mesylate Dihydrate, 10 mM in DMSO
  • 149676-40-4
  • C17H20FN3O3x2H2O
  • C17H20FN3O3x2022CH4O3Sx20222H2O
  • C18H24FN3O6S2H2O
  • C18H24FN3O6S
  • C17H20FN3O3CH4O3S2H2O
  • C18H28FN3O8S
  • MYCOSPOR