ChemicalBook > CAS DataBase List > 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

Product Name: 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
CAS No.: 149676-40-4
Chemical Name: 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
Synonyms: EU-5306;RB-1589;PERFLOXACINE;PEFLOXACIN METHANESULFONATE;Pefloxacin Mesylate dihydra;PEFLOXACIN MESYLATE DIHYDRATE;Pefloxacin (mesylate hydrate);PEFLOXACINE MESYLATE DIHYDRATE;Pefloxacin mesylate dihydrdate;Pefloxacin dihydrate mesylate
CBNumber: CB7748671
Molecular Formula: C18H28FN3O8S
Formula Weight: 465.49
MOL File: 149676-40-4.mol

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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Property

Melting point:: 271°C
Boiling point:: 529℃
Flash point:: >110°(230°F)
storage temp.: Inert atmosphere,2-8°C
solubility: H2O: soluble50mg/mL
form: powder
Water Solubility: Freely soluble in water
Sensitive: Light Sensitive
CAS DataBase Reference: 149676-40-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26
WGK Germany: 3
RTECS: VB2002200
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0309000
Product name: Pefloxacin mesilate dihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 200 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: P0106
Product name: Pefloxacin mesylate dihydrate
Packaging: 10g
Price: $76.2
Updated: 2025/07/31

Sigma-Aldrich

Product number: P0309000
Product name: Pefloxacin mesilate dihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: p0309000
Price: $153
Updated: 2024/03/01

TCI Chemical

Product number: P3024
Product name: Pefloxacine Mesylate Dihydrate
Packaging: 5G
Price: $130
Updated: 2025/07/31

Cayman Chemical

Product number: 29103
Product name: Pefloxacin (mesylate hydrate)
Packaging: 10g
Price: $37
Updated: 2024/03/01

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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

antifungal, calmodulin antagonist

Uses

Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase.

Biological Activity

Pefloxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited . Pefloxacin is an analog of norfloxacin.

IC 50

Quinolone

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID manufacturers

Dideu Industries Group Limited

Product: 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID 149676-40-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-19

Career Henan Chemical Co

Product: 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID 149676-40-4
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-24

149676-40-4, 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACIDRelated Search:

Pefloxacin Pefloxacin mesylate Danofloxacin mesylate Levofloxacin mesylate 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

RB-1589

PERFLOXACINE

PEFLOXACINE MESYLATE DIHYDRATE

PEFLOXACINE METHANSULFONATE DIHYDRATE

PEFLOXACIN MESYLATE DIHYDRATE

PEFLOXACIN METHANESULFONATE

PEFLOXACIN METHANE SULFONATE DIHYDRATE

EU-5306

Pefloxacinium mesylate dihydrate

1-ETHYL-6-FLUORO-1,4-DIHYDRO-7-(4-METHYL-1-PIPERAZINYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID) METHANE SULPHONATE DIHYDRATE

Pefloxacin dihydrate mesylate

Pefloxacine monomethanesulfonate dihydrate, Pefloxacinium methanesulfonate dihydrate, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate

/1-ethyl-6-fluoro-7-(4-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid coMpound with Methanesulfonic acid (1:1

3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-Methyl-1-piperazinyl)-4-oxo-, Methanesulfonate, hydrate (1:1:2)

Pefloxacin Mesylate dihydra

3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate

Pefloxacine monomethanesulfonate dihydrate

Pefloxacinium methanesulfonate dihydrate

Pefloxacin mesylate`Pefloxacin mesylate dihydrate

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID USP/EP/BP

1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid mesylate dihydrate

Pefloxacin mesylate dihydrdate

Pefloxacin dihydrate methanesulfonate

1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-Quinolinecarboxylic acid methanesulfonate hydrate (1:1:2)

Pefloxacin (mesylate hydrate)

/1-Ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinolin-3-carboxylic acid compound with methanesulfonic acid (1:1

1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound with methanesulfonic acid (1:1) hydrate

Pefloxacin Mesylate Dihydrate, 10 mM in DMSO

Pefloxacin for system suitability CRS

1-Ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid compound with methanesulfonic acid hydrate

149676-40-4

C17H20FN3O3x2H2O

C17H20FN3O3x2022CH4O3Sx20222H2O

C18H24FN3O6S2H2O

C18H24FN3O6S

C17H20FN3O3CH4O3S2H2O

C18H28FN3O8S

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