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Ethyl p-toluenesulfonate

Product Name
Ethyl p-toluenesulfonate
CAS No.
80-40-0
Chemical Name
Ethyl p-toluenesulfonate
Synonyms
Ethyl 4-methylbenzenesulfonate;ETHYL P-TOSYLATE;Mittel AEP;ETHYL TOSYLATE;ethyl p-methylbenzenesulfonate;4-METHYLBENZENESULFONIC ACID, ETHYL ESTER;ethylpts;NSC 8887;Ethyl p-TS;Ethyl p-toluenesulfo
CBNumber
CB7750825
Molecular Formula
C9H12O3S
Formula Weight
200.25
MOL File
80-40-0.mol
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Ethyl p-toluenesulfonate Property

Melting point:
29-33 °C(lit.)
Boiling point:
158-162 °C10 mm Hg(lit.)
Density 
1.174 g/mL at 25 °C(lit.)
vapor pressure 
0.6 hPa (14 °C)
refractive index 
n20/D 1.511(lit.)
Flash point:
316 °F
storage temp. 
2-8°C
solubility 
1.24g/l
form 
Liquid After Melting
color 
Clear colorless to pale brown
Water Solubility 
Insoluble
Sensitive 
Moisture Sensitive
Merck 
14,3858
BRN 
611213
CAS DataBase Reference
80-40-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzenesulfonic acid, 4-methyl-, ethyl ester(80-40-0)
EPA Substance Registry System
Benzenesulfonic acid, 4-methyl-, ethyl ester (80-40-0)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-40-22
Safety Statements 
26-45-36/37/39
RIDADR 
UN2811
WGK Germany 
3
RTECS 
XT6825000
21
Autoignition Temperature
500 °C
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29041000
Hazardous Substances Data
80-40-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.08332
Product name
Ethyl 4-toluenesulfonate
Purity
for synthesis
Packaging
100g
Price
$43.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08332
Product name
Ethyl 4-toluenesulfonate
Purity
for synthesis
Packaging
500g
Price
$129
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08332
Product name
Ethyl 4-toluenesulfonate
Purity
for synthesis
Packaging
5kg
Price
$433
Updated
2024/03/01
Sigma-Aldrich
Product number
104256
Product name
Ethyl p-toluenesulfonate
Purity
98%
Packaging
50g
Price
$28.6
Updated
2024/03/01
Sigma-Aldrich
Product number
104256
Product name
Ethyl p-toluenesulfonate
Purity
98%
Packaging
1kg
Price
$238
Updated
2024/03/01
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Ethyl p-toluenesulfonate Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to brownish liquid after melting

Uses

Ethyl p-toluenesulfonate was used to develop an extraction method for methyl and ethyl esters of various sulfonic acids in active pharmaceutical ingredients using solid-phase micro extraction coupled to GC/MS in the selected ion monitoring mode. It was used in a study to develop a fast and accurate method for determination of residues of some common alkylating agents employed in drug synthesis by in situ derivatization-headspace-gas chromatography-mass spectrometry.

Uses

Ethyl p-toluenesulfonate can be used in the manufacture of organic synthesis, and also can be used as intermediate of methylation reagent and sensitive material. It also is flexibilizer of cellulose acetate.

Uses

For ethylation.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 34, p. 2710, 1986 DOI: 10.1248/cpb.34.2710
The Journal of Organic Chemistry, 39, p. 3454, 1974 DOI: 10.1021/jo00937a050

Safety Profile

Moderately toxic by subcutaneous and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2, dry chemical. When heated to decomposition it emits hlghly toxic fumes of SOx. See also SULFONATES and ESTERS.

Ethyl p-toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl p-toluenesulfonate Suppliers

ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from Ethyl p-toluenesulfonate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl p-toluenesulfonate 80-40-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Hebei Yanxi Chemical Co., Ltd.
Product
Ethyl p-toluenesulfonate 80-40-0
Price
US $20.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-10
Shouguang Nuomeng Chemical Co Ltd.
Product
Ethyl P-toluenesulfonate, PTSE, P-Toluene sulfonic acid ethyl Ester 80-40-0
Price
US $5800.00/T
Min. Order
1KG
Purity
98% Min.
Supply Ability
200 tons per month
Release date
2020-07-21

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