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GLYCOFUROL

Product Name
GLYCOFUROL
CAS No.
31692-85-0
Chemical Name
GLYCOFUROL
Synonyms
TETRAGLYCOL;THFP;GLYCOFUROL;TETRAGLYCO;Glycofural;Glycofurol75;Glycofurolum 75;GLYCOFUROL-SPECIAL;GLYCOFUROL TETRAGLYCOL;Tetraglycol ( Glycofurol)
CBNumber
CB7756948
Molecular Formula
C11H21O5R
Formula Weight
233.28
MOL File
31692-85-0.mol
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GLYCOFUROL Property

Boiling point:
100-145 °C0.4 mm Hg
Density 
1.09 g/mL at 25 °C(lit.)
vapor pressure 
4.97-37.4Pa at 20-50℃
refractive index 
n20/D 1.462(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
Chloroform (Sparingly), Methanol (Slightly, Sonicated)
form 
Oil
color 
Colourless
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
-1.21--0.38
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Safety

WGK Germany 
3
RTECS 
MD0907500
HS Code 
3907 20 20
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3396
Product name
Tetraglycol
Purity
BioXtra
Packaging
1kg
Price
$322
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21092
Product name
Tetrahydrofurfuryl alcohol polyethylene glycol ether
Purity
forsynthesis
Packaging
100mL
Price
$81.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21092
Product name
Tetrahydrofurfuryl alcohol polyethylene glycol ether
Purity
forsynthesis
Packaging
250ML
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21092
Product name
Tetrahydrofurfuryl alcohol polyethylene glycol ether
Purity
forsynthesis
Packaging
10Kg
Price
$1610
Updated
2024/03/01
Sigma-Aldrich
Product number
T3396
Product name
Tetraglycol
Purity
BioXtra
Packaging
100g
Price
$64
Updated
2024/03/01
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GLYCOFUROL Chemical Properties,Usage,Production

Chemical Properties

Glycofurol is a clear, colorless, almost odorless liquid, with a bitter taste; it produces a warm sensation on the tongue.

Uses

Glycofurol is used as a carrier device for drug delivery.

Uses

Used as solvent to dissolve water-insoluble compounds.

Production Methods

Glycofurol is prepared by the reaction of tetrahydrofurfuryl alcohol with ethylene oxide (followed by a special purification process in the case of Glycofurol 75).

Pharmaceutical Applications

Glycofurol is used as a solvent in parenteral products for intravenous or intramuscular injection in concentrations up to 50% v/v. It has also been investigated, mainly in animal studies, for use as a penetration enhancer and solvent in topical and intranasal formulations. Glycofurol has also been used at 20% v/v concentration in a rectal formulation.

Safety

Glycofurol is mainly used as a solvent in parenteral pharmaceutical formulations and is generally regarded as a relatively nontoxic and nonirritant material at the levels used as a pharmaceutical excipient. Glycofurol can be irritant when used undiluted; its tolerability is approximately the same as propylene glycol.
Glycofurol may have an effect on liver function and may have a low potential for interaction with hepatoxins or those materials undergong extensive hepatic metabolism.
LD50 (mouse, IV): 3.5 mL/kg

storage

Stable if stored under nitrogen in a well-closed container protected from light, in a cool, dry place.

Incompatibilities

Incompatible with oxidizing agents.

Regulatory Status

Included in parenteral medicines licensed in Europe.

GLYCOFUROL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GLYCOFUROL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Glycofurol 31692-85-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95%-100%
Supply Ability
10kg
Release date
2021-05-28
Henan Bao Enluo International TradeCo.,LTD
Product
GLYCOFUROL 31692-85-0
Price
US $100.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
500t/month
Release date
2023-05-25
Shaanxi Dideu Medichem Co. Ltd
Product
GLYCOFUROL 31692-85-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-04-23

31692-85-0, GLYCOFUROLRelated Search:


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