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GLYCOFUROL

Product Name
GLYCOFUROL
CAS No.
31692-85-0
Chemical Name
GLYCOFUROL
Synonyms
TETRAGLYCOL;THFP;GLYCOFUROL;TETRAGLYCO;Glycofural;GLYCOFUROL;Glycofurol75;Glycofurolum 75;GLYCOFUROL-SPECIAL;GLYCOFUROL TETRAGLYCOL
CBNumber
CB7756948
Molecular Formula
C11H21O5R
Formula Weight
233.28
MOL File
31692-85-0.mol
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GLYCOFUROL Property

Melting point:
≤ -100 °C
Boiling point:
100-145 °C0.4 mm Hg
Density 
1.09 g/mL at 25 °C(lit.)
vapor pressure 
4.97-37.4Pa at 20-50℃
refractive index 
n20/D 1.462(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
Chloroform (Sparingly), Methanol (Slightly, Sonicated)
form 
Oil
color 
Colourless
Water Solubility 
water: soluble 3420g/L
α-end
tetrahydrofurfuryl ether
Ω-end
hydroxyl
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
-1.21--0.38
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Safety

WGK Germany 
3
RTECS 
MD0907500
HS Code 
3907 20 20
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3396
Product name
Tetraglycol
Purity
BioXtra
Packaging
1kg
Price
$331
Updated
2025/07/31
Sigma-Aldrich
Product number
8.21092
Product name
Tetrahydrofurfuryl alcohol polyethylene glycol ether
Purity
forsynthesis
Packaging
100mL
Price
$71.2
Updated
2025/07/31
Sigma-Aldrich
Product number
8.21092
Product name
Tetrahydrofurfuryl alcohol polyethylene glycol ether
Purity
forsynthesis
Packaging
250ML
Price
$151
Updated
2025/07/31
Sigma-Aldrich
Product number
8.21092
Product name
Tetrahydrofurfuryl alcohol polyethylene glycol ether
Purity
forsynthesis
Packaging
10Kg
Price
$1650
Updated
2025/07/31
Sigma-Aldrich
Product number
T3396
Product name
Tetraglycol
Purity
BioXtra
Packaging
100g
Price
$65.8
Updated
2025/07/31
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GLYCOFUROL Chemical Properties,Usage,Production

Chemical Properties

Glycofurol is a clear, colorless, almost odorless liquid, with a bitter taste; it produces a warm sensation on the tongue.

Uses

Glycofurol is used as a carrier device for drug delivery.

Uses

Used as solvent to dissolve water-insoluble compounds.

Production Methods

Glycofurol is prepared by the reaction of tetrahydrofurfuryl alcohol with ethylene oxide (followed by a special purification process in the case of Glycofurol 75).

Pharmaceutical Applications

Glycofurol is used as a solvent in parenteral products for intravenous or intramuscular injection in concentrations up to 50% v/v. It has also been investigated, mainly in animal studies, for use as a penetration enhancer and solvent in topical and intranasal formulations. Glycofurol has also been used at 20% v/v concentration in a rectal formulation.

Biological Activity

Liquid glycofurol can readily transform into gel systems with excellent elasticity due to which, it can be used as a medium to dissolve water-insoluble drugs.

Safety

Glycofurol is mainly used as a solvent in parenteral pharmaceutical formulations and is generally regarded as a relatively nontoxic and nonirritant material at the levels used as a pharmaceutical excipient. Glycofurol can be irritant when used undiluted; its tolerability is approximately the same as propylene glycol.
Glycofurol may have an effect on liver function and may have a low potential for interaction with hepatoxins or those materials undergong extensive hepatic metabolism.
LD50 (mouse, IV): 3.5 mL/kg

storage

Stable if stored under nitrogen in a well-closed container protected from light, in a cool, dry place.

Incompatibilities

Incompatible with oxidizing agents.

Regulatory Status

Included in parenteral medicines licensed in Europe.

GLYCOFUROL Preparation Products And Raw materials

Raw materials

Preparation Products

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GLYCOFUROL Suppliers

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View Lastest Price from GLYCOFUROL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Glycofurol 31692-85-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95%-100%
Supply Ability
10kg
Release date
2021-05-28
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
GLYCOFUROL 31692-85-0
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-15
Hebei Zhuanglai Chemical Trading Co Ltd
Product
GLYCOFUROL 31692-85-0
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-12-18

31692-85-0, GLYCOFUROLRelated Search:

Furfuryl alcohol Tetrahydrofurfuryl alcohol GLYCOFUROL,GLYCOFUROL TETRAGLYCOL NIERICINE NA-SALT cationomycin MONENSIN DECYL ESTER MONENSIN, [3H(G)] Monensin, 16-deethyl-3-O-demethyl-16-methyl-3-O-(1-oxopropyl)- SODIUM 4-[2-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-OXAN-2-YL]-3-METHYL-OXOLAN-2-YL]-OXOLAN-2-YL]-9-HYDROXY-2,8-DIMETHYL-1,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE Monensin NIGERICIN SODIUM SALT kijimicin AKOS NCG1-0012 monensin methyl ester Monensin sodium salt GLYCOFUROL

  • Glycols,polyethylene,mono(tetrahydrofurfuryl)ether
  • tetrahydrofurfurylalkoholpolyaethylenglycolaether
  • THFP
  • Tetraglycol,Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether
  • POLY(ETHYLENE GLYCOL) TETRAHYDROFURFURYL ETHER
  • TETRAHYDROFURFURYL POLYETHYLENE GLYCOL 200
  • TETRAHYDROFURFURYL ALCOHOL POLYETHYLENEGLYCOL ETHER
  • TETRAGLYCOL
  • Tetrahydrofurfuryl polyethylene glycol ether
  • GLYCOFUROL
  • GLYCOFUROL TETRAGLYCOL
  • TETRAGLYCO
  • Tetraglycol ( Glycofurol)
  • TetrahydrofurfurylAlcoholPEGether
  • Poly(oxy-1,2-ethanediyl), .alpha.-(tetrahydro-2-furanyl)methyl-.omega.-hydroxy-
  • mixture of diethylene and triethylene glycol mono-tetrahydrofurfuryl ether
  • 2-ethanediyl),alpha-[(tetrahydro-2-furanyl)methyl]-omega-hydroxy-Poly(oxy-1
  • alpha-((tetrahydro-2-furanyl)methyl)-omega-hydroxy-poly(oxy-2-ethanediyl)
  • Glycofurol75
  • GLYCOFUROL-SPECIAL
  • 2-(oxolan-2-ylmethoxy)ethanol
  • Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether
  • Tetrahydrofurfuryl polyethylene glycol 200, Mixture of diethylene and triethylene glycol mono-tetrahydrofurfuryl ether
  • alpha-((Tetrahydro-2-furanyl)methyl)-omega-hydroxy-poly(oxy-1,2-E- thanediyl)
  • Ethylene oxide homopolymer 2-tetrahydrofuranylmethyl ether
  • Glycofural
  • Glycofurolum 75
  • TETRAHYDROFURFURYL ALCOHOL POLYETHYLENE
  • GLYCOFUROL ISO 9001：2015 REACH
  • Poly(oxy-1,2-ethanediyl),a-[(tetrahydro-2-furanyl)methyl]-w-hydroxy-
  • Glycofurol extrapure, 99%
  • Reaction products of tetrahydrofurfuryl alcohol with ethylene oxide
  • GLYCOFUROL
  • 31692-85-0
  • C2H4OnC5H10O2
  • HOCH2CH2O4H
  • Biochemicals and Reagents
  • BioChemical
  • Carbohydrates
  • Monosaccharide
  • Heterobifunctional PEGs
  • Materials Science
  • Poly(ethylene glycol) and Poly(ethylene oxide)
  • Polymer Science
  • Polymers