1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE

Product Name: 1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE
CAS No.: 35454-39-8
Chemical Name: 1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE
Synonyms: hydrochloride - [M86572];1-METHYL-4-IMIDAZOLE ACETIC ACID HCL;1-Methyl-15N2-imidazol-4-yl acetic acid HCl;2-(1-METHYL-1H-IMIDAZOL-4-YL)ACETIC ACID HCL;1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE;MECHAN. MEASURING STATION, AMELUNG*NO. D10013;1-MethyliMidazole-4-acetic acid hydrochloride;1-METHYL-4-IMIDAZOLEACETIC ACID HYDROGEN CHLORIDE;1-methyl-1H-imidazol-4-acetic acid monohydrochloride;(1-Methyl-1H-imidazol-4-yl)-acetic acid hydrochloride
CBNumber: CB7759318
Molecular Formula: C6H9ClN2O2
Formula Weight: 176.6
MOL File: 35454-39-8.mol

More

Less

1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE Property

Melting point:: 204-206℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: Light Beige to Beige
Stability:: Hygroscopic

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 18815
Product name: 1-Methyl-4-imidazoleacetic Acid (hydrochloride)
Purity: ≥95%
Packaging: 10mg
Price: $41
Updated: 2024/03/01

Cayman Chemical

Product number: 18815
Product name: 1-Methyl-4-imidazoleacetic Acid (hydrochloride)
Purity: ≥95%
Packaging: 50mg
Price: $183
Updated: 2024/03/01

Cayman Chemical

Product number: 18815
Product name: 1-Methyl-4-imidazoleacetic Acid (hydrochloride)
Purity: ≥95%
Packaging: 100mg
Price: $322
Updated: 2024/03/01

Cayman Chemical

Product number: 18815
Product name: 1-Methyl-4-imidazoleacetic Acid (hydrochloride)
Purity: ≥95%
Packaging: 250mg
Price: $702
Updated: 2024/03/01

TRC

Product number: M323800
Product name: 1-Methyl-4-imidazoleaceticAcidHydrochloride
Packaging: 250mg
Price: $640
Updated: 2021/12/16

More

Less

1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production

Description

1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.

Uses

1-Methyl-4-imidazoleacetic Acid Hydrochloride is a metabolite of histamine (H436500), which is produced by mast cells and involved with the inflammatory response. 1-Methyl-4-imidazoleacetic Acid Hydrochloride can also be used to synthesize N-[1-(9,10-methano-9-anthracenylmethyl)-4-piperidinyl]alkanamides and analogs as dopamine D2 receptor antagonists.

References

[1] KERR J W. IDENTIFICATION OF HISTAMINE METABOLITE 1-METHYL, 4-IMIDAZOLE ACETIC ACID IN HUMAN URINE AND ITS ABSENCE IN STATUS ASTHMATICUS.[J]. BMJ?: British Medical Journal, 1964, 2 5409: 606-608. DOI: 10.1136/bmj.2.5409.606
[2] J. J. VAN DOORMAAL. Tryptase and histamine metabolites as diagnostic indicators of indolent systemic mastocytosis without skin lesions[J]. Allergy, 2012, 67 5: 683-690. DOI: 10.1111/j.1398-9995.2012.02809.x
[3] BYRTHE J.P.R. VOS BSC Pieter C van V V M Eveline van der Veer PhD, PHD André B M M, PHD , et al. Diminished reliability of tryptase as risk indicator of mastocytosis in older overweight subjects[J]. Journal of Allergy and Clinical Immunology, 2015, 135 3: Pages 792-798. DOI: 10.1016/j.jaci.2014.05.047
[4] A. TSOLAKIS. Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours.[C]//21 47 1. 2015: 13240-13249. DOI: 10.3748/wjg.v21.i47.13240

1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE Suppliers

China 42 Germany 1 India 1 Switzerland 1 United States 7 Global 52

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Proactive Molecular Research

Tel: --
Fax: --
Email: tony@proactivemr.com
Country: United States
ProdList: 895
Advantage: 0

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

35454-39-8, 1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDERelated Search:

METHYL 2-(6-CHLOROIMIDAZO[1,2-A]PYRIDIN-2-YL)ACETATE (1H-IMIDAZOL-4-YL)-ACETALDEHYDE Imidazole-4-acetic acid (1-METHYL-1H-IMIDAZOL-4-YL)-ACETIC ACID 2-(3H-imidazol-4-yl)acetic acid 4-IMIDAZOLEACETIC ACID HYDROCHLORIDE (1-METHYL-1H-IMIDAZOL-4-YL)-ACETALDEHYDE 1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE Imidazolyl-4-ethanol 2-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)acetic acid BASIONIC(TM) AC 75 (6-CHLORO-IMIDAZO[1,2-A]PYRIDIN-2-YL)-ACETIC ACID

1-METHYL-4-IMIDAZOLE ACETIC ACID HCL

1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE

1-methyl-1H-imidazol-4-acetic acid monohydrochloride

MECHAN. MEASURING STATION, AMELUNG*NO. D10013

1-METHYL-4-IMIDAZOLEACETIC ACID HYDROGEN CHLORIDE

1-MethyliMidazole-4-acetic acid hydrochloride

2-(1-Methyl-1H-imidazol-4-yl)ethanoic acid hydrochloride

2-(1-Methyl-1H-imidazol-4-yl)acetic acid hydrochloride

2-(1-METHYL-1H-IMIDAZOL-4-YL)ACETIC ACID HCL

(1-Methyl-1H-imidazol-4-yl)-acetic acid hydrochloride

1H-Imidazole-4-aceticacid, 1-methyl-, hydrochloride (1:1)

1-Methyl-15N2-imidazol-4-yl acetic acid HCl

hydrochloride - [M86572]

35454-39-8

Heterocyclic Building Blocks

Imidazoles

Building Blocks

Heterocyclic Compounds