(R)-(+)-1,2-Dithiolane-3-pentanoic acid
- Product Name
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid
- CAS No.
- 1200-22-2
- Chemical Name
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid
- Synonyms
- (R)-LIPOIC ACID;R-ALPHA-LIPOIC ACID;Thiogamma;Tiobe;Lipoec;Tiobec;(R)-(+)-α;ipoic acid;(R)-(+)-α-L;D-lipoic acid
- CBNumber
- CB7765979
- Molecular Formula
- C8H14O2S2
- Formula Weight
- 206.33
- MOL File
- 1200-22-2.mol
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Property
- Melting point:
- 48-52 °C(lit.)
- Boiling point:
- 185-195 °C(Press: 0.5 Torr)
- alpha
- D23 +104° (c = 0.88 in benzene)
- Density
- 1.218±0.06 g/cm3(Predicted)
- refractive index
- 114 ° (C=1, EtOH)
- Flash point:
- >230 °F
- storage temp.
- -20°C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), DMSO
- form
- Solid
- pka
- 5.4(at 25℃)
- color
- Light Yellow to Yellow
- optical activity
- [α]20/D +104°, c = 1 in chloroform
- Merck
- 14,9326
- LogP
- 2.160 (est)
- CAS DataBase Reference
- 1200-22-2(CAS DataBase Reference)
Safety
- Risk Statements
- 22-36/38
- Safety Statements
- 20-36-26-35
- WGK Germany
- 3
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 07039
- Product name
- (R)-(+)-α-Lipoic acid
- Purity
- ≥98.0% (HPLC)
- Packaging
- 10mg
- Price
- $72.4
- Updated
- 2024/03/01
- Product number
- 04471
- Product name
- (R)-(+)-α-Lipoic acid
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $208
- Updated
- 2024/03/01
- Product number
- L0207
- Product name
- (R)-alpha-Lipoic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $100
- Updated
- 2024/03/01
- Product number
- L0207
- Product name
- (R)-alpha-Lipoic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $182
- Updated
- 2024/03/01
- Product number
- 27299
- Product name
- (R)-α-Lipoic Acid
- Packaging
- 5g
- Price
- $86
- Updated
- 2024/03/01
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Chemical Properties,Usage,Production
Chemical Properties
Yellow Crystalline Solid
Uses
A fat-metabolism stimulator
Uses
α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.
Definition
ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.
General Description
α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-(+)-1,2-Dithiolane-3-pentanoic acid manufacturers
- Product
- (R)-(+)-Lipoic acid 1200-22-2
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/Week
- Release date
- 2024-04-30
- Product
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid 1200-22-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2023-08-07
- Product
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid 1200-22-2
- Price
- US $50.00-40.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20
- Release date
- 2023-10-11