(R)-(+)-1,2-Dithiolane-3-pentanoic acid

Product Name: (R)-(+)-1,2-Dithiolane-3-pentanoic acid
CAS No.: 1200-22-2
Chemical Name: (R)-(+)-1,2-Dithiolane-3-pentanoic acid
Synonyms: (R)-LIPOIC ACID;R-ALPHA-LIPOIC ACID;Thiogamma;Tiobe;Lipoec;Tiobec;(R)-(+)-α;ipoic acid;(R)-(+)-α-L;D-lipoic acid
CBNumber: CB7765979
Molecular Formula: C8H14O2S2
Formula Weight: 206.33
MOL File: 1200-22-2.mol

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(R)-(+)-1,2-Dithiolane-3-pentanoic acid Property

Melting point:: 48-52 °C(lit.)
Boiling point:: 185-195 °C(Press: 0.5 Torr)
alpha: D23 +104° (c = 0.88 in benzene)
Density: 1.218±0.06 g/cm3(Predicted)
refractive index: 114 ° (C=1, EtOH)
Flash point:: >230 °F
storage temp.: -20°C
solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO
form: Solid
pka: 5.4(at 25℃)
color: Light Yellow to Yellow
optical activity: [α]20/D +104°, c = 1 in chloroform
Merck: 14,9326
LogP: 2.160 (est)
CAS DataBase Reference: 1200-22-2(CAS DataBase Reference)

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Safety

Risk Statements: 22-36/38
Safety Statements: 20-36-26-35
WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 07039
Product name: (R)-(+)-α-Lipoic acid
Purity: ≥98.0% (HPLC)
Packaging: 10mg
Price: $72.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 04471
Product name: (R)-(+)-α-Lipoic acid
Purity: analytical standard
Packaging: 100mg
Price: $208
Updated: 2024/03/01

TCI Chemical

Product number: L0207
Product name: (R)-alpha-Lipoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $100
Updated: 2024/03/01

TCI Chemical

Product number: L0207
Product name: (R)-alpha-Lipoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $182
Updated: 2024/03/01

Cayman Chemical

Product number: 27299
Product name: (R)-α-Lipoic Acid
Packaging: 5g
Price: $86
Updated: 2024/03/01

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(R)-(+)-1,2-Dithiolane-3-pentanoic acid Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Solid

Uses

A fat-metabolism stimulator

Uses

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

Definition

ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.

General Description

α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.

Biochem/physiol Actions

(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-(+)-1,2-Dithiolane-3-pentanoic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: (R)-(+)-Lipoic acid 1200-22-2
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/Week
Release date: 2024-04-30

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-α-Lipoic Acid 1200-22-2
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%HPLC; USP
Supply Ability: 500KGS
Release date: 2021-06-04

Hebei Weibang Biotechnology Co., Ltd

Product: (R)-(+)-1,2-Dithiolane-3-pentanoic acid 1200-22-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-21

1200-22-2, (R)-(+)-1,2-Dithiolane-3-pentanoic acidRelated Search:

DL-1,2-DITHIOLANE-3-PENTANOIC ACID REDUCED FORM α-Lipoic Acid Lipoic acid tromethamine salt (R)-6,8-Dimercaptooctanoic acid Sodium thioctate OCTOTIAMINE 1,2,3-Trithiane-4-pentanoic Acid Lipoic Acid Related CoMpound rac α-Lipoic Acid-d5 R-Lipoic Acid Impurity 1 (S-Oxide) Sodium (R)-alpha-lipoate R-alpha-Lipoic acid tromethamine salt 1,2-Dithiolane-3-pentanoic acid 1,2-Dithiolane-3-pentanoic acid 1-oxide (S)-1,2-Dithiolane-3-pentanoic acid,1,2-Dithiolane-3-pentanoic acid, (S)-,1,2-Dithiolane-3-pentanoic acid, (3S)- (9CI) DL-1,2-DITHIOLANE-3-PENTANOIC ACID (+/-)-1,2-Dithiolane-3-pentanoic Acid-d5 (R)-1,2-Dithiolane-3-pentanoic acid polymer with 2-hydroxypropanoic ac id

5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid

5-[(3R)-dithiolan-3-yl]pentanoic acid

5-[(3R)-dithiolan-3-yl]valeric acid

(R)-(+)-1,2-Dithiola

(R)-5-(1,2-Dithiolan-3-yl)pentanoic acid

(R)-Thioctic Acid (R)-1,2-Dithiolane-3-valeric Acid

D-lipoic acid

(R)-(+)-1,2-Dithiolane-3-pentanoic acid 97%

(R)-LIPOIC ACID Acid

(R)-(+)-Lipoic acid,(R)-(+)-Thioctic acid,(R)-(+)- 1,2-Dithiolane-3-pentanoic acid

Lipoic acid ((R)-(+)-α-Lipoic acid

(R)-alpha-Thioctic Acid

Thioctic Acid Impurity 19

(R)-LIPOIC ACID

R-(+)-ALPHA-LIPOIC ACID

R-ALPHA-LIPOIC ACID

(R)-(+)-1,2-DITHIOLANE-3-PENTANOIC ACID

(R)-(+)-Thioctic Acid

R-(+)-Alpha-Lipoic Acid 1200-22-2

(3R)-1,2-Dithiolane-3-pentanoic Acid

(R)-(+)-a-Lipoic Acid

Byodinoral 300

Lipoec

Thiogamma

Tiobe

1,2-Dithiolane-3-pentanoic acid, (3R)-

LIPOIC ACID (D-LIPOIC ACID)

R-A-LIPOIC ACID (D-LIPOIC ACID)

1,2-Dithiolane-3-pentanoic acid, (3R)- (9CI)

1,2-Dithiolane-3-pentanoic acid, (R)-

Tiobec

(R)-1,2-Dithiolane-3-valeric Acid

R (+) Alpha lipoic Acid ( D-Form)

(R)-α-LipoicAcid&gt

ipoic acid

(R)-(+)-α-Lipoic acid

(R)-(+)-α-L

(R)-lipoicaci

DITHIOLANE-3-PENTANOIC ACID

Lipoic Acid [R-(+)-Thioctic acid

(R)-(+)-α

1200-22-2

200-22-2

Asymmetric Synthesis

Chiral Building Blocks

Heterocyclic Building Blocks

Others

API

Sulfur & Selenium Compounds

Chiral Building Blocks

Heterocyclic Building Blocks

Others

Chiral Reagents

Heterocycles

FINE Chemical & INTERMEDIATES

1200-22-2