FMOC-VAL-OSU

Product Name: FMOC-VAL-OSU
CAS No.: 130878-68-1
Chemical Name: FMOC-VAL-OSU
Synonyms: FMOC-VAL-OSU;Fmoc-Val-0su;Fmoc-L-Val-OSu;FMOC-VALINE-OSU;Fmoc-L-valine-osu;FMOC-VAL-OSUFMOC-V;Fmoc-Val-OSu, 98%, Fmoc-amino acids;N-Fmoc-L-valine N-succinimidyl ester;Trastuzumab Impurity 1 (Fmoc-Val-Osu);N-Fmoc-L-valineN-succinimidylester,95%
CBNumber: CB7779662
Molecular Formula: C24H24N2O6
Formula Weight: 436.46
MOL File: 130878-68-1.mol

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FMOC-VAL-OSU Property

Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 10.09±0.46(Predicted)
form: Powder
color: Off-white to white
optical activity: Consistent with structure
Water Solubility: Slightly soluble in water.

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Safety

Safety Statements: 24/25
HS Code: 29251900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 450869
Product name: Fmoc-Val-Osu
Packaging: 100mg
Price: $305
Updated: 2021/12/16

Usbiological

Product number: 276075
Product name: Fmoc-L-valine N-hydroxysuccinimide ester
Packaging: 25g
Price: $523
Updated: 2021/12/16

TRC

Product number: F861083
Product name: Fmoc-Val-Osu
Packaging: 1g
Price: $75
Updated: 2021/12/16

TRC

Product number: F861083
Product name: Fmoc-Val-Osu
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK598773
Product name: Fmoc-Val-OSu,98%,Fmoc-aminoacids
Packaging: 1g
Price: $46
Updated: 2021/12/16

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FMOC-VAL-OSU Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

N-Fmoc-L-valine N-succinimidyl ester is useful for solid phase peptide synthesis techniques.

Synthesis

6066-82-6

68858-20-8

130878-68-1

Dicyclohexylcarbodiimide (1.55 g, 7.52 mmol) and N-hydroxysuccinimide (762 mg, 6.63 mmol) were sequentially added to a stirred solution of Fmoc-L-valine (1.5 g, 4.42 mmol) in dichloromethane (25 mL) at room temperature. The reaction mixture was stirred continuously for 3 hours at room temperature. Upon completion of the reaction, the white solid dicyclohexylurea produced in the reaction was removed by filtration. The organic phase was washed sequentially with 0.1 N HCl solution and deionized water, followed by drying with anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by fast column chromatography using 1% dichloromethane solution in methanol as eluent to give the final target product (S)-2,5-dioxopyrrolidin-1-yl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutyrate as a white solid (1.7 g, 89% yield). Mass spectrum (MS): m/z 459 [M + Na]+. 1H NMR (400 MHz, CDCl3) δ 7.80 (d, J = 7.5 Hz, 2H), 7.68-7.55 (m, 2H), 7.43 (t, J = 7.4 Hz, 2H), 7.34 (dd, J = 15.9, 8.5 Hz, 2H), 4.70 (d, J = 4.6 Hz, 1H), 4.56-4.40 (m, 3H), 4.28 (t, J = 6.6 Hz, 1H), 2.85 (s, 4H), 2.37 (dd, J = 12.3, 6.5 Hz, 1H), 1.08 (dd, J = 11.0, 6.9 Hz, 6H).

References

[1] Journal of Pharmaceutical Sciences, 1994, vol. 83, # 7, p. 999 - 1005
[2] Langmuir, 2010, vol. 26, # 7, p. 4990 - 4998
[3] Patent: WO2018/178060, 2018, A1. Location in patent: Page/Page column 64-66
[4] Journal of the American Chemical Society, 2015, vol. 137, # 21, p. 6932 - 6940
[5] Patent: US2017/247324, 2017, A1. Location in patent: Paragraph 0284; 0285

FMOC-VAL-OSU Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-VAL-OSU Suppliers

China 143 Germany 3 India 5 United Kingdom 1 United States 14 Global 166

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
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Beijing HwrkChemical Technology Co., Ltd

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Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
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Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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GL Biochem (Shanghai) Ltd

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Email: ymbetter@glbiochem.com
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Beijing Ouhe Technology Co., Ltd

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Fax: +86-10-82967029
Email: 2355560935@qq.com
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
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Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
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Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
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ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
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View Lastest Price from FMOC-VAL-OSU manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: FMOC-VAL-OSU 130878-68-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-04-21

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc-L-Val-Osu 130878-68-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-03-22

Sichuan Jiaying Lai Technology Co.,LTD

Product: fmoc-val-osu 130878-68-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-24

130878-68-1, FMOC-VAL-OSURelated Search:

Fmoc-THr(Bzl)-OH FMOC-PRO-OPFP FMOC-D-MET-OPFP FMOC-L-Valine FMOC-D-VAL-OPFP FMOC-TYR(TBU)-OPFP FMOC-TYR(SO3H)-OH SODIUM SALT FMOC-D-TYR(TBU)-OPFP FMOC-D-PRO-OPFP FMOC-D-SER(TBU)-OPFP FMOC-D-THR(TBU)-OPFP L-Valine FMOC-GLY-OSU FMOC-ILE-OSU FMOC-ALA-OSU FMOC-VAL-OSU FMOC-VAL-OSU FMOC-L-VALINOL

CarbaMic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-Methylpropyl]-, 9H-fluoren-9-ylMethyl ester, (S)-

L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinyl ester

N-Fmoc-L-valine N-succinimidyl ester

Fmoc-L-valineN-hydroxysuccinimide ester≥ 99% (HPLC)

FMOC-L-VALINE N-HYDROXYSUCCINIMIDE ESTER

FMOC-VAL-OSU

FMOC-VALINE-OSU

NALPHA-9-Fluorenylmethoxycarbonyl-L-valine N-hydroxysuccinimide ester

Fmoc-L-Val-OSu

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-valine succinimidyl ester

(S)-2,5-dioxopyrrolidin-1-yl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methylbutanoate

N-alpha-FMoc-L-valine N-hydroxysucciniMide ester

[(1S)-1-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl] 9H-fluoren-9-ylmethyl carbamate

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine 2,5-dioxo-1-pyrrolidinyl ester

(9H-Fluoren-9-yl)MethOxy]Carbonyl Val-OSu

Fmoc-Val-OSu, 98%, Fmoc-amino acids

FMOC-VAL-OSUFMOC-V

2,5-dioxopyrrolidin-1-yl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoate

N-Fmoc-L-valineN-succinimidylester,95%

Fmoc-L-valine-osu

Trastuzumab Impurity 1 (Fmoc-Val-Osu)

Fmoc-Val-0su

2,5-dioxopyrrolidin-1-yl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-valinate

130878-68-1

Fmoc-Amino Acids and Derivatives

Fmoc-Amino acid series

Amino Acids