ChemicalBook > CAS DataBase List > Methyl palmitate

Methyl palmitate

Product Name
Methyl palmitate
CAS No.
112-39-0
Chemical Name
Methyl palmitate
Synonyms
METHYL HEXADECANOATE;C16;HEXADECANOIC ACID METHYL ESTER;PALMITIC ACID METHYL ESTER;Hexadecanoic;n-Hexadecanoic acid methyl ester;METHYL PALMITATE, STANDARD FOR GC;mitate;Emery 2216;Radia 7120
CBNumber
CB7783577
Molecular Formula
C17H34O2
Formula Weight
270.45
MOL File
112-39-0.mol
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Methyl palmitate Property

Melting point:
32-35 °C (lit.)
Boiling point:
185 °C/10 mmHg (lit.)
Density 
0.852 g/mL at 25 °C (lit.)
vapor pressure 
0.008Pa at 25℃
refractive index 
n20/D 1.4512(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Liquid or Low Melting Solid
Specific Gravity
0.852
color 
Clear colorless
Odor
at 100.00 %. oily waxy fatty orris
Odor Type
waxy
Water Solubility 
INSOLUBLE
BRN 
1780973
LogP
7.38 at 36℃
CAS DataBase Reference
112-39-0(CAS DataBase Reference)
NIST Chemistry Reference
Hexadecanoic acid, methyl ester(112-39-0)
EPA Substance Registry System
Methyl palmitate (112-39-0)
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Safety

Safety Statements 
22-24/25
WGK Germany 
1
TSCA 
Yes
HS Code 
29157090
Hazardous Substances Data
112-39-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3538
Product name
Methyl Palmitate
Purity
pharmaceutical secondary standard, certified reference material
Packaging
1G
Price
$287
Updated
2024/03/01
Sigma-Aldrich
Product number
76159
Product name
Methyl palmitate
Purity
analytical standard
Packaging
1g
Price
$24
Updated
2024/03/01
Sigma-Aldrich
Product number
1431603
Product name
Methyl palmitate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
3X100MG
Price
$394
Updated
2024/03/01
TCI Chemical
Product number
P0006
Product name
Methyl Palmitate
Purity
>97.0%(GC)
Packaging
25g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
P0006
Product name
Methyl Palmitate
Purity
>97.0%(GC)
Packaging
250g
Price
$36
Updated
2024/03/01
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Methyl palmitate Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid or low melting solid. Soluble in alcohol, acetone, chloroform and benzene, soluble in ether, insoluble in water.

Uses

Methyl palmitate is used in the preparation of detergents, emulsifiers, wetting agents, stabilizers, resins, lubricants, plasticizers and animal feeds. It exhibits an anti-inflammatory and anti-fibrotic agent and prevents bleomycin-induced lung inflammation and fibrosis in rats. In addition, it also prevents carbon tetrachloride-induced liver fibrosis linked to reduce transforming growth factor beta, which is a secreted protein that controls proliferation, cellular differentiation and other functions in most cells.

Uses

Methyl palmitate can be used as an additive in food and cosmetic industries for the stabilization of fats and oil products by slowing down the auto-oxidation of unsaturated fatty acids.

Application

Methyl Palmitate is a fatty acid ester essential oil that naturally occurs in many plant species. Methyl Palmitate concentration in cells are known to be modulated by methanol. In experimental studies with isolated Kupffer cells, Methyl palmitate exhibited inhibitory activity towards phagocytosis and decreases cell viability.

Definition

ChEBI: Methyl palmitate is a fatty acid methyl ester. It has a role as a metabolite.

Biological Functions

Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long- term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake, and approximately 25% of the total plasma fatty acids in plasma lipoproteins. Saturated free fatty acids induce the expression of cyclooxygenase-2. Palmitic acid methyl ester (MP) is a fatty acid ester whose concentration in cells is modulated by methanol. In studies with isolated Kupffer cells, MP inhibits phagocytosis and decreases cell viability. In cells treated with lipopolysaccharide, it also decreases secretion of interleukin-10, TNF-α, nitric oxide, and prostaglandin E2. This effect is thought to occur by the inhibition of NF-κB.

Synthesis Reference(s)

Synthetic Communications, 16, p. 1423, 1986 DOI: 10.1080/00397918608056391

General Description

Methyl palmitate (PAME), a fatty acid ester of palmitic acid, is a muscurinic receptors antagonist. Methyl palmitate functions as a vasodilator and relaxes the arterioles in retina upon electrical depolarization. In the superior cervical ganglion, methyl palmitate modulates nicotinic receptor. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. PAME activates Kv7 channels and promotes perivascular adipose tissue.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Methyl palmitate has anti-inflammatory and anti-fibrotic effect. Methyl palmitate prevents bleomycin-induced lung inflammation and fibrosis in rats, by inhibiting NF-κB . Methyl palmitate also prevents CCl4-induced liver fibrosis linked to reduced TGF-β .

Methyl palmitate Preparation Products And Raw materials

Raw materials

Palmitic acid

Preparation Products

4-Morpholineethanesulfonic acid
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Methyl palmitate Suppliers

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View Lastest Price from Methyl palmitate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Methyl palmitate 112-39-0
Price
US $80.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-06-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Methyl palmitate 112-39-0
Price
US $0.00/Kg/Drum
Min. Order
180KG
Purity
98%min
Supply Ability
250tons/month
Release date
2021-06-03
Shanghai UCHEM Inc.
Product
Methyl palmitate 112-39-0
Price
US $44.00/kg
Min. Order
1kg
Purity
0.98
Supply Ability
100kg
Release date
2023-11-10

112-39-0, Methyl palmitateRelated Search:

Palmitic acid Isooctyl palmitate Sodium Palmitate 4-NITROPHENYL PALMITATE Palmitoyl chloride PHYTANTRIOL Kavain PALMITOYL CARNITINE Carnauba wax PALMITIC ACID N-BUTYL ESTER 1,2-DILINOLEOYL-3-PALMITOYL-RAC-GLYCEROL 1,3-DIOLEOYL-2-PALMITOYL-GLYCEROL PALM OIL Levetiracetam acid Palmitoyl Tripeptide 38 Fatty acids, palm-oil Glycidyl Palmitate KYVUJPJYTYQNGJ-XBHHEOLKSA-N Palmitic Acid Methyl Ester

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