4-AMINO-2-METHOXY-BENZONITRILE
- Product Name
- 4-AMINO-2-METHOXY-BENZONITRILE
- CAS No.
- 7251-09-4
- Chemical Name
- 4-AMINO-2-METHOXY-BENZONITRILE
- Synonyms
- NSC 30614;5-Amino-2-cyanoanisole;4-Cyano-3-Methoxyaniline;4-AMINO-2-METHOXY-BENZONITRILE;Benzonitrile,4-aMino-2-Methoxy-;4-Amino-2-methoxybenzonitrile >
- CBNumber
- CB7797806
- Molecular Formula
- C8H8N2O
- Formula Weight
- 148.16
- MOL File
- 7251-09-4.mol
4-AMINO-2-METHOXY-BENZONITRILE Property
- Melting point:
- 102℃
- Boiling point:
- 351.2±27.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 1.30±0.10(Predicted)
- color
- White to Light yellow
- InChI
- InChI=1S/C8H8N2O/c1-11-8-4-7(10)3-2-6(8)5-9/h2-4H,10H2,1H3
- InChIKey
- KTDRJLRJAHBQDQ-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC=C(N)C=C1OC
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- A2785
- Product name
- 4-Amino-2-methoxybenzonitrile
- Purity
- >97.0%(GC)(T)
- Packaging
- 1g
- Price
- $151
- Updated
- 2025/07/31
- Product number
- A2785
- Product name
- 4-Amino-2-methoxybenzonitrile
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $454
- Updated
- 2025/07/31
- Product number
- A898160
- Product name
- 4-Amino-2-methoxybenzonitrile
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 119619
- Product name
- 4-Amino-2-methoxybenzonitrile
- Purity
- 95+%
- Packaging
- 5g
- Price
- $918
- Updated
- 2021/12/16
- Product number
- J51115
- Product name
- 4-Amino-2-methoxybenzonitrile
- Packaging
- 10g
- Price
- $550
- Updated
- 2021/12/16
4-AMINO-2-METHOXY-BENZONITRILE Chemical Properties,Usage,Production
Synthesis
101084-96-2
7251-09-4
1. 2-Methoxy-4-nitrobenzonitrile (750 mg, 4.21 mmol) and palladium catalyst (50 mg, 0.47 mmol) were dissolved in methanol (15 mL) at room temperature. 2. The reaction system was subjected to a hydrogen atmosphere (1 atm) with continuous stirring for 48 h. 3. Upon completion of the reaction the palladium catalyst was removed by filtration. 4. The filtrate was concentrated under reduced pressure to give the brownish-red powdery product 4-amino-2-methoxybenzonitrile (679 mg, 4.58 mmol, quantitative yield). 5. The structure of the product was determined by 1H-anionic digestion. 6. The filtrate was concentrated under reduced pressure to give a brown-red powdery product, 4-amino-2-methoxybenzonitrile (679 mg, 4.58 mmol, quantitative yield). 5. The structure of the product was confirmed by 1H-NMR (300 MHz, DMSO-d6): δ 3.32 (3H, s), 6.05-6.29 (4H, m), 7.23 (1H, d, J = 8.3 Hz). ).
References
[1] Patent: EP2759533, 2014, A1. Location in patent: Paragraph 0484; 0485
[2] Synthesis, 2006, # 19, p. 3316 - 3340
[3] Chemistry - A European Journal, 2014, vol. 20, # 31, p. 9504 - 9509
[4] Chemical and Pharmaceutical Bulletin, 2014, vol. 62, # 10, p. 979 - 988
[5] Patent: US2009/42967, 2009, A1. Location in patent: Page/Page column 22
4-AMINO-2-METHOXY-BENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-AMINO-2-METHOXY-BENZONITRILE manufacturers
- Product
- 4-AMINO-2-METHOXY-BENZONITRILE 7251-09-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500KG
- Release date
- 2018-08-19