SR 11302

Product Name: SR 11302
CAS No.: 160162-42-5
Chemical Name: SR 11302
Synonyms: SR 11302;RQANARBNMTXCDM-DKOHIBGUSA-N;(2E,4E,6Z,8E)-3-Methyl-7-(p-tolyl)-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;(E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoicacid;2,4,6,8-Nonatetraenoic acid, 3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E,4E,6Z,8E)-;acid,SR11302,retinoid,SR-11302,Lung,RARE,Cancer,response,Inhibitor,protein-1,SR 11302,inhibit,AP-1,retinoic,element,activator
CBNumber: CB7844692
Molecular Formula: C26H32O2
Formula Weight: 376.53
MOL File: 160162-42-5.mol

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SR 11302 Property

Boiling point:: 541.6±30.0 °C(Predicted)
Density: 1.048±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: crystalline solid
pka: 4.67±0.33(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16338
Product name: SR 11302
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 16338
Product name: SR 11302
Purity: ≥95%
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 16338
Product name: SR 11302
Purity: ≥95%
Packaging: 10mg
Price: $235
Updated: 2024/03/01

Cayman Chemical

Product number: 16338
Product name: SR 11302
Purity: ≥95%
Packaging: 25mg
Price: $479
Updated: 2024/03/01

Tocris

Product number: 2476
Product name: SR11302
Purity: ≥98%(HPLC)
Packaging: 10
Price: $231
Updated: 2021/12/16

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SR 11302 Chemical Properties,Usage,Production

Description

The receptors for retinoids, RARs and RXRs, induce transcriptional activation by binding the specific retinoid response elements, RARE and RXRE. Alternatively, retinoid receptors interact with and modulate other transcription factors, including activator protein-1 (AP-1). SR 11302 is a synthetic retinoid that inhibits AP-1 activity without activating transcription through RARE. It significantly suppresses both AP-1 activation and phorbol ester-induced papilloma formation in mice when applied topically (0.1 μM). SR 11302 is used to elucidate the role of AP-1 in various signaling pathways.

Uses

SR 11302 is an inhibitor of activator protein-1.

Biological Activity

Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumor effects in vivo . Does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC 50 > 1 μ M for RAR α , RAR β , RAR γ and RXR α ).

storage

Store at -20°C

SR 11302 Preparation Products And Raw materials

Raw materials

Preparation Products

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SR 11302 Suppliers

China 55 Germany 1 United Kingdom 2 United States 8 Global 66

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

160162-42-5, SR 11302Related Search:

Retinal SR 11302 Retinoic acid Vitamin A

SR 11302

(E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoicacid

RQANARBNMTXCDM-DKOHIBGUSA-N

2,4,6,8-Nonatetraenoic acid, 3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E,4E,6Z,8E)-

(2E,4E,6Z,8E)-3-Methyl-7-(p-tolyl)-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

acid,SR11302,retinoid,SR-11302,Lung,RARE,Cancer,response,Inhibitor,protein-1,SR 11302,inhibit,AP-1,retinoic,element,activator

160162-42-5