ChemicalBook > CAS DataBase List > 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
- Product Name
- 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
- CAS No.
- 105628-72-6
- Chemical Name
- 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
- Synonyms
- Ha 1100;Fasudil Impurity L;Fasudil Impurity 5;1-[(1,2-DIHYDRO-1-OX;HA 1100 HYDROCHLORIDE;HA-1100;HA 1100;HA1100;HYDROXYFASUDIL;HA-1100;HA 1100;HA1100;5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol;5-((1,4-Diazepan-1-yl)sulfonyl)isoquinolin-1(2H)-one;5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1(8aH)-one
- CBNumber
- CB7847446
- Molecular Formula
- C14H17N3O3S
- Formula Weight
- 307.37
- MOL File
- 105628-72-6.mol
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1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE Property
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Soluble in DMSO
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Safety
- Toxicity
- mouse,LD50,unreported,145mg/kg (145mg/kg),United States Patent Document. Vol. #4678783,
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Tocris
- Product number
- 2415
- Product name
- HA1100hydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $244
- Updated
- 2021/12/16
Usbiological
- Product number
- 255432
- Product name
- HA 1100 hydrochloride
- Packaging
- 10mg
- Price
- $516
- Updated
- 2021/12/16
AK Scientific
- Product number
- 3044AH
- Product name
- 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine
- Packaging
- 5mg
- Price
- $258
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A3478
- Product name
- Hydroxyfasudil
- Packaging
- 10mg
- Price
- $126
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-1599
- Product name
- Hydroxyfasudil
- Purity
- 98.11%
- Packaging
- 10mg
- Price
- $136
- Updated
- 2021/12/16
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1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE Chemical Properties,Usage,Production
Biological Activity
Cell-permeable active metabolite of Fasudil (HA 1077; Fasudil hydrochloride). Produces ATP-competitive and reversible inhibition of Rho-kinase and is ~ 100-fold selective over a range of other protein kinases. Inhibits neutrophil migration and produces potent vasodilatory effects in vivo .
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE manufacturers
Career Henan Chemical Co
- Product
- 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE 105628-72-6
- Price
- US $1.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1lg; 2kg; 5kg; 10kg; 100kg
- Release date
- 2019-08-31
105628-72-6, 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINERelated Search:
5-Quinolinesulfonic acid, 2-methyl-
Fasudil Impurity 6
Fasudil Impurity 13
Fasudil Pyridine N-Oxide TFA Salt
Fasudil Impurity 9
Fasudil Impurity 34
Fasudil iMpurity
Fasudil Impurity 7
1-[(1-Chloro-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine
Fasudil Impurity 8
1-Chloro-5-isoquinolinesulfonic Acid
Fasudil Impurity 6
1,4-ditosyl-1,4-diazepane
Fasudil diMer
Fasudil N-hydroxy iMpurity
N-(3-HYDROXYPROPYL)ETHYLENEDIAMINE
Isoquinoline
HYDROXYFASUDIL MONOHYDROCHLORIDE