ChemicalBook > CAS DataBase List > 1-(4-Hydroxyphenyl)piperazine

1-(4-Hydroxyphenyl)piperazine

Product Name
1-(4-Hydroxyphenyl)piperazine
CAS No.
56621-48-8
Chemical Name
1-(4-Hydroxyphenyl)piperazine
Synonyms
4-PIPERAZINOPHENOL;RARECHEM AH CK 0119;SALOR-INT L497754-1EA;LABOTEST-BB LT00233198;4-(1-PIPERAZINO)PHENOL;4-(1-PIPERAZINYL)PHENOL;4-PIPERAZIN-1-YL-PHENOL;p-(1-piperazinyl)phenol;Ketoconazole Impurity 32;4-(1-Piperazino)phenol,98%
CBNumber
CB7853850
Molecular Formula
C10H14N2O
Formula Weight
178.23
MOL File
56621-48-8.mol
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1-(4-Hydroxyphenyl)piperazine Property

Melting point:
220 °C
Boiling point:
371.3±27.0 °C(Predicted)
Density 
1.141±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
12.18±0.30(Predicted)
color 
Brownish
BRN 
150964
InChI
InChI=1S/C10H14N2O/c13-10-3-1-9(2-4-10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2
InChIKey
GPEOAEVZTOQXLG-UHFFFAOYSA-N
SMILES
C1(O)=CC=C(N2CCNCC2)C=C1
LogP
0.374
CAS DataBase Reference
56621-48-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
UN3263
WGK Germany 
3
10-34
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
III
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
H0891
Product name
1-(4-Hydroxyphenyl)piperazine
Purity
>98.0%(GC)
Packaging
25g
Price
$94
Updated
2025/07/31
TCI Chemical
Product number
H0891
Product name
1-(4-Hydroxyphenyl)piperazine
Purity
>98.0%(GC)
Packaging
250g
Price
$556
Updated
2025/07/31
Matrix Scientific
Product number
074304
Product name
1-(4-Hydroxyphenyl)piperazine
Purity
95+%
Packaging
10g
Price
$47
Updated
2021/12/16
ChemScene
Product number
CS-W017311
Product name
4-(Piperazin-1-yl)phenol
Purity
>97.0%
Packaging
100g
Price
$60
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK109970
Product name
1-(4-Hydroxyphenyl)piperazine
Purity
98%
Packaging
5g
Price
$69
Updated
2021/12/16
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1-(4-Hydroxyphenyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

brownish powder

Uses

1-(4-Hydroxyphenyl)piperazine can be used as an intermediate for ketoconazole.

1-(4-Hydroxyphenyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-Hydroxyphenyl)piperazine Suppliers

Shanghai Jinhuan Chemical Co.,LTD.
Tel
+86-21-52210535 +86-13162045318
Fax
+86-21-67285091
Email
sales@jinhchem.com
Country
China
ProdList
491
Advantage
58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868361
Fax
QQ1907456386
Email
sales11@btcpharm.com
Country
China
ProdList
1250
Advantage
58
BTC Pharmaceutical CO. Ltd
Tel
15716293042 18862996710
Fax
0513-68015394
Email
15050603958@163.com
Country
China
ProdList
694
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2809
Advantage
65
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
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View Lastest Price from 1-(4-Hydroxyphenyl)piperazine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-(1-Piperazino)phenol 56621-48-8
Price
US $2.00-5.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons
Release date
2025-07-10
Henan Aochuang Chemical Co.,Ltd.
Product
1-(4-Hydroxyphenyl)piperazine 56621-48-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Career Henan Chemical Co
Product
1-(4-Hydroxyphenyl)piperazine 56621-48-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-25

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