ChemicalBook > CAS DataBase List > 4-(1-Acetylpiperazin-4-yl)phenol

4-(1-Acetylpiperazin-4-yl)phenol

Product Name
4-(1-Acetylpiperazin-4-yl)phenol
CAS No.
67914-60-7
Chemical Name
4-(1-Acetylpiperazin-4-yl)phenol
Synonyms
1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE;AHPP;keto06;TIMTEC-BB SBB003353;Ketoconazole Impurity;LABOTEST-BB LT00440741;Ketoconazole Impurity 13;Branchedchainofketoconazole;4-(4-Acetylpiperazino)phenol;1-Acetyl-4-(4-hydroxyphenyl)pi
CBNumber
CB4329307
Molecular Formula
C12H16N2O2
Formula Weight
220.27
MOL File
67914-60-7.mol
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4-(1-Acetylpiperazin-4-yl)phenol Property

Melting point:
180-185 °C (lit.)
Boiling point:
361.21°C (rough estimate)
Density 
1.1115 (rough estimate)
vapor pressure 
0Pa at 20℃
refractive index 
1.6000 (estimate)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
12.18±0.30(Predicted)
color 
White to slightly pink or beige
Water Solubility 
4.3 g/L (20 ºC)
BRN 
795777
InChIKey
AGVNLFCRZULMKK-UHFFFAOYSA-N
LogP
0.3
CAS DataBase Reference
67914-60-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-36/37/39-22
WGK Germany 
3
HS Code 
29214910
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
511943
Product name
1-Acetyl-4-(4-hydroxyphenyl)piperazine
Purity
98%
Packaging
25g
Price
$31.5
Updated
2023/06/20
TCI Chemical
Product number
A1845
Product name
1-Acetyl-4-(4-hydroxyphenyl)piperazine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
A1845
Product name
1-Acetyl-4-(4-hydroxyphenyl)piperazine
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$122
Updated
2024/03/01
Alfa Aesar
Product number
B22083
Product name
1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98%
Packaging
100g
Price
$81
Updated
2021/12/16
Alfa Aesar
Product number
B22083
Product name
1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98%
Packaging
25g
Price
$26.9
Updated
2021/12/16
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4-(1-Acetylpiperazin-4-yl)phenol Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine. It may also be used in the multi-step synthesis of ketoconazole, its 1,2,4-triazole and thiazole analogs.

General Description

1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen. Its multi-step preparation using bis-(2-chloroethyl)amine hydrochloride and p-aminophenol as starting materials has been reported.2

Flammability and Explosibility

Not classified

4-(1-Acetylpiperazin-4-yl)phenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(1-Acetylpiperazin-4-yl)phenol Suppliers

Conier Chem & Pharma Co.,Ltd,
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023-62879767 13996269627;
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+86-28-84559521
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sales@conier.com
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China
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Jinan Dexinjia Bio&Tech Co., Ltd
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0531-8237592 15562613975
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0531-82375893
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3416953599@qq.com
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China
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Shanghai Jinhuan Chemical Co.,LTD.
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+86-21-52210535 +86-13162045318
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China
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BTC Pharmaceutical CO. Ltd
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0513-0513-68015-397-397 15716293042
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0513-68015394
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sales14@btcpharm.com
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China
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J & K SCIENTIFIC LTD.
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86-10-82849933
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jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006608290; 18621169109
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86-21-61259102
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market03@meryer.com
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China
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INTATRADE GmbH
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+49 3493/605464
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+49 3493/605470
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sales@intatrade.de
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Germany
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future industrial shanghai co., ltd
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400-0066400 13621662912
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021-55660885
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sales@jonln.com
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China
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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View Lastest Price from 4-(1-Acetylpiperazin-4-yl)phenol manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4-(1-Acetylpiperazin-4-yl)phenol 67914-60-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-17
Qiuxian Baitai New Material Co., LTD
Product
1- acetyl -4-(4-hydroxyphenyl) piperazine 67914-60-7
Price
US $1.00/g
Min. Order
1KG
Purity
99%
Supply Ability
5ton/Month
Release date
2021-12-21
Shaanxi Dideu Medichem Co. Ltd
Product
4-(1-Acetylpiperazin-4-yl)phenol 67914-60-7
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24

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