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Isobutyric anhydride

Product Name
Isobutyric anhydride
CAS No.
97-72-3
Chemical Name
Isobutyric anhydride
Synonyms
Isobutylic anhydride;Isobutyric acid anhydride;2-METHYLPROPANOIC ANHYDRIDE;Isobutyric anhydride, distilled;(iso-C3H7CO)2O;isobutyryloxide;Isobutyl Anhydride;sobutyric anhydride;isobutyrylanhydride;ISOBUTRIC ANHYDRIDE
CBNumber
CB7854736
Molecular Formula
C8H14O3
Formula Weight
158.2
MOL File
97-72-3.mol
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Isobutyric anhydride Property

Melting point:
-56 °C (lit.)
Boiling point:
182 °C (lit.)
Density 
0.954 g/mL at 25 °C (lit.)
vapor density 
5.45 (vs air)
vapor pressure 
10 mm Hg ( 67 °C)
refractive index 
n20/D 1.406(lit.)
Flash point:
152 °F
storage temp. 
Store below +30°C.
form 
Liquid
color 
Clear colorless
explosive limit
1.09%, 87°F
Water Solubility 
decomposes
Sensitive 
Moisture Sensitive
BRN 
386267
Exposure limits
ACGIH: TWA 10 ppm
NIOSH: TWA 10 ppm(30 mg/m3); STEL 15 ppm(45 mg/m3)
Dielectric constant
13.9(20℃)
LogP
1.1 at 25℃
CAS DataBase Reference
97-72-3(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, 2-methyl-, anhydride(97-72-3)
EPA Substance Registry System
Isobutyric anhydride (97-72-3)
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Safety

Hazard Codes 
C
Risk Statements 
34-21/22
Safety Statements 
26-36/37/39-45
RIDADR 
2922
WGK Germany 
3
RTECS 
NQ5550000
13-21
Autoignition Temperature
624 °F
TSCA 
Yes
HS Code 
2915 90 70
HazardClass 
8
PackingGroup 
II
Hazardous Substances Data
97-72-3(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 266 mg/kg LD50 dermal Rabbit 475 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
245771
Product name
Isobutyric anhydride
Purity
97%
Packaging
25ml
Price
$30.4
Updated
2024/03/01
Sigma-Aldrich
Product number
245771
Product name
Isobutyric anhydride
Purity
97%
Packaging
2l
Price
$152
Updated
2024/03/01
TCI Chemical
Product number
I0111
Product name
Isobutyric Anhydride
Purity
>95.0%(GC)(T)
Packaging
25mL
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
I0111
Product name
Isobutyric Anhydride
Purity
>95.0%(GC)(T)
Packaging
500mL
Price
$52
Updated
2024/03/01
Alfa Aesar
Product number
L13240
Product name
Isobutyric anhydride, 97%
Packaging
100ml
Price
$15.65
Updated
2024/03/01
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Isobutyric anhydride Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Chemical intermediate.

Uses

Isobutyric anhydride was used in the synthesis of 4-O-isobutyryl derivative via reaction with octyl β-D-glucopyranoside in the presence of C2-symmetric chiral 4-pyrrolidinopyridine as a catalyst.

Preparation

Isobutyric anhydride is prepared from iso-Butyryl chloride and Sodium acetate, or: from iso-Butyryl chloride and Butyric acid with a catalyst.

Definition

ChEBI: An acyclic carboxylic anhydride of isobutyric acid. Metabolite observed in cancer metabolism.

General Description

A colorless liquid. Flash point 139°F. Burns skin and eyes. Vapors are heavier than air.

Air & Water Reactions

Flammable. Reacts exothermically with water or moisture-containing materials to form isobutyric acid.

Reactivity Profile

Isobutyric anhydride reacts exothermically with water. The reactions are sometimes slow, but can become violent when local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with a cids, strong oxidizing agents, alcohols, amines, and bases.

Hazard

Strong irritant to tissue.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

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Isobutyric anhydride Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
Camida
Tel
--
Fax
--
Email
info@camida.com
Country
Europe
ProdList
3704
Advantage
71
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View Lastest Price from Isobutyric anhydride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Isobutyric anhydride 97-72-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-18
Hebei Chuanghai Biotechnology Co,.LTD
Product
Isobutyric Anhydride Anib 97-72-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
10 ton
Release date
2024-08-20
Hebei Mojin Biotechnology Co., Ltd
Product
Isobutyric anhydride 97-72-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-28

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