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cloprednol

Product Name
cloprednol
CAS No.
5251-34-3
Chemical Name
cloprednol
Synonyms
RS-4691;Synestan;Novacort;Syntestan;Cloradryn;cloprednol;Cloprednole;cloprednol USP/EP/BP;Benzoyl Peroxide Impurity 11;Methylprednisolone Impurity 33 (Cloprednol)
CBNumber
CB7875380
Molecular Formula
C21H25ClO5
Formula Weight
392.876
MOL File
5251-34-3.mol
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cloprednol Property

Melting point:
>125°C (dec.)
Boiling point:
600.3±55.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Ethyl Acetate (Slightly), Methanol (Slightly)
pka
12.30±0.70(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C587295
Product name
Cloprednol
Packaging
5mg
Price
$670
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
68837
Product name
Cloprednol
Packaging
0.5mg
Price
$675
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20516
Product name
Cloprednol
Packaging
25mg
Price
$1911
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
68837
Product name
Cloprednol
Packaging
5mg
Price
$2575
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20516
Product name
Cloprednol
Packaging
1mg
Price
$174.9
Updated
2021/12/16
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cloprednol Chemical Properties,Usage,Production

Originator

Syntestan,Syntex,W. Germany,1980

Uses

A systematic corticosteroid. Anti-inflammatory.

Definition

ChEBI: Cloprednol is a 21-hydroxy steroid.

Manufacturing Process

A mixture of 5 g of the 21-acetate of 6α-chlorohydrocortisone, 7 g of chloranil and 100 cc of n-amyl alcohol was refluxed for 16 hours, cooled and diluted with ether. The solution was successively washed with water, 5% sodium carbonate solution and water, dried over anhydrous sodium sulfate, filtered and evaporated to dryness under reduced pressure. Chromatographic purification of the residue yielded the 21-acetate of 6-chloro-δ1,4,6- pregnatriene-11β,17α,21-triol-3,20-dione.

Therapeutic Function

Glucocorticoid

cloprednol Preparation Products And Raw materials

Raw materials

Preparation Products

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cloprednol Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10005
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58

5251-34-3, cloprednolRelated Search:


  • (11β)-6-Chloro-11,17,21-trihydroxypregna-1,4,6-triene-3,20-dione
  • Cloprednole
  • 6-Chloro-11β,17,21-trihydroxypregna-1,4,6-triene-3,20-dione
  • RS-4691
  • Syntestan
  • cloprednol
  • Cloradryn
  • Novacort
  • Synestan
  • 6-Chloro-11beta,17,21-trihydroxypregna-1,4,6-triene-3,20-dione
  • Pregna-1,4,6-triene-3,20-dione, 6-chloro-11,17,21-trihydroxy-, (11β)-
  • cloprednol USP/EP/BP
  • (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
  • Methylprednisolone Impurity 33 (Cloprednol)
  • Benzoyl Peroxide Impurity 11
  • 5251-34-3
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids