cloprednol
- Product Name
- cloprednol
- CAS No.
- 5251-34-3
- Chemical Name
- cloprednol
- Synonyms
- RS-4691;Synestan;Novacort;Syntestan;Cloradryn;cloprednol;Cloprednole;cloprednol USP/EP/BP;Benzoyl Peroxide Impurity 11;Methylprednisolone Impurity 33 (Cloprednol)
- CBNumber
- CB7875380
- Molecular Formula
- C21H25ClO5
- Formula Weight
- 392.876
- MOL File
- 5251-34-3.mol
cloprednol Property
- Melting point:
- >125°C (dec.)
- Boiling point:
- 600.3±55.0 °C(Predicted)
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- 12.30±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P314Get medical advice/attention if you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C587295
- Product name
- Cloprednol
- Packaging
- 5mg
- Price
- $670
- Updated
- 2021/12/16
- Product number
- 68837
- Product name
- Cloprednol
- Packaging
- 0.5mg
- Price
- $675
- Updated
- 2021/12/16
- Product number
- FC20516
- Product name
- Cloprednol
- Packaging
- 25mg
- Price
- $1911
- Updated
- 2021/12/16
- Product number
- 68837
- Product name
- Cloprednol
- Packaging
- 5mg
- Price
- $2575
- Updated
- 2021/12/16
- Product number
- FC20516
- Product name
- Cloprednol
- Packaging
- 1mg
- Price
- $174.9
- Updated
- 2021/12/16
cloprednol Chemical Properties,Usage,Production
Originator
Syntestan,Syntex,W. Germany,1980
Uses
A systematic corticosteroid. Anti-inflammatory.
Definition
ChEBI: Cloprednol is a 21-hydroxy steroid.
Manufacturing Process
A mixture of 5 g of the 21-acetate of 6α-chlorohydrocortisone, 7 g of chloranil and 100 cc of n-amyl alcohol was refluxed for 16 hours, cooled and diluted with ether. The solution was successively washed with water, 5% sodium carbonate solution and water, dried over anhydrous sodium sulfate, filtered and evaporated to dryness under reduced pressure. Chromatographic purification of the residue yielded the 21-acetate of 6-chloro-δ1,4,6- pregnatriene-11β,17α,21-triol-3,20-dione.
Therapeutic Function
Glucocorticoid