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azidamfenicol

Product Name
azidamfenicol
CAS No.
13838-08-9
Chemical Name
azidamfenicol
Synonyms
azidamfenicol;azidoamphenicol;AZIAMPHENICOL, PHARMA;AzidoaMphenicol, LeukoMycin N;azidamfenicol ISO 9001：2015 REACH;Ketoprofen Impurity 13(S-Isomer) Trometamol;2-azido-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide;2-Azido-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-nitrophenyl)ethyl]acetamide;Acetamide, 2-azido-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-;Antibiotic,Bacterial,bacteria,Azidamfenicol,Inhibitor,peptidyltransferase,Gram-positive,Gram-negative,inhibit,ribosomal
CBNumber
CB7884098
Molecular Formula
C11H13N5O5
Formula Weight
295.254
MOL File
13838-08-9.mol
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azidamfenicol Property

Melting point:
107°
alpha 
D20 -20° (c = 1.6 in ethyl acetate)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Ethyl Acetate (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25449
Product name
Azidamfenicol
Purity
≥99%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
25449
Product name
Azidamfenicol
Purity
≥99%
Packaging
5mg
Price
$216
Updated
2024/03/01
TRC
Product number
A926853
Product name
Azidamfenicol
Packaging
5mg
Price
$1620
Updated
2021/12/16
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azidamfenicol Chemical Properties,Usage,Production

Originator

Berlicetin-,Chauvin

Uses

Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in 1959. Azidamfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Azidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Azidamfenicol has received little research attention with only a few literature citations.

Definition

ChEBI: Azidamfenicol is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

Manufacturing Process

21.2 g of D-(-)-threo-1-p-nitrophenyl-2-aminopropane-1,3-diol are stirred with 10 g of azidoacetonitrile (B.P. 68°C/25 mm) in a mixture of 125 ml of methanol and 125 ml of water at 30-40°C for a few days. The mixture is filtered off from a little undissolved base and the solvent is distilled in vacuo. The residue is treated with a little normal hydrochloric acid until acid to Congo red and extracted with ethylacetate. By evaporating the solvent and recrystallizing the residue from ethylene chloride is obtained D-(-)-threo-1-pnitrophenyl- 2-azidoacetylamino-propane-1,3-diol, M.P. 107°C.

Therapeutic Function

Antibiotic

azidamfenicol Preparation Products And Raw materials

Raw materials

Preparation Products

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azidamfenicol Suppliers

China 36 Germany 1 United Kingdom 1 United States 7 Global 45
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
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32165
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58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
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58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
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58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52925
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58
Cayman Chemical Company
Tel
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Fax
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Email
cayman@caymanchem.com
Country
United States
ProdList
6213
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81
United States Biological
Tel
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Email
chemicals@usbio.net
Country
United States
ProdList
6214
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80
MedChemExpress
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Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58

13838-08-9, azidamfenicolRelated Search:

Ethyl acetate Chloramphenicol azidamfenicol 2-Amino-1-(4-nitrophenyl)-1,3-propanediol

  • azidamfenicol
  • AZIAMPHENICOL, PHARMA
  • azidoamphenicol
  • 2-Azido-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-nitrophenyl)ethyl]acetamide
  • AzidoaMphenicol, LeukoMycin N
  • 2-azido-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
  • azidamfenicol ISO 9001：2015 REACH
  • Antibiotic,Bacterial,bacteria,Azidamfenicol,Inhibitor,peptidyltransferase,Gram-positive,Gram-negative,inhibit,ribosomal
  • Ketoprofen Impurity 13(S-Isomer) Trometamol
  • Acetamide, 2-azido-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
  • 13838-08-9