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alminoprofen

Product Name
alminoprofen
CAS No.
39718-89-3
Chemical Name
alminoprofen
Synonyms
EB 382;Minalfen;Minalfene;alminoprofen;Alminoprofene;Alminoprofeno;rac AlMinoprofen;alminoprofen USP/EP/BP;ALMINOPROFEN(FORR&DONLY);Alminoprofene [inn-french]
CBNumber
CB7885929
Molecular Formula
C13H17NO2
Formula Weight
219.28
MOL File
39718-89-3.mol
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alminoprofen Property

Melting point:
107°
Boiling point:
360.1°C (rough estimate)
Density 
1.0697 (rough estimate)
refractive index 
1.5100 (estimate)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.86±0.50(Predicted)
color 
Light Brown
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Safety

Toxicity
LD50 orally in mice: 2400 mg/kg (Dumaitre)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A575150
Product name
racAlminoprofen
Packaging
1g
Price
$790
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003395
Product name
ALMINOPROFEN
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003395
Product name
ALMINOPROFEN
Purity
95.00%
Packaging
2.5G
Price
$2255
Updated
2021/12/16
ChemScene
Product number
CS-0009220
Product name
Alminoprofen
Purity
99.35%
Packaging
100mg
Price
$275
Updated
2021/12/16
ChemScene
Product number
CS-0009220
Product name
Alminoprofen
Purity
99.35%
Packaging
250mg
Price
$450
Updated
2021/12/16
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alminoprofen Chemical Properties,Usage,Production

Description

Alminoprofen is an arylpropionic acid analgesic/antiinflammatory agent indicated for the short term management of dental, traumatic and postpartum pain.

Originator

Labs. Dr. E. Bouchara (France)

Uses

Alminoprofen is a nonsteroidal antiinflammatory drugs (NSAID) of the phenylpropionic acid class. Alminoprofen maybe a useful therapeutic option in the management of immune dysfunction in rheumatoid ar thritis.

Definition

ChEBI: A substituted aniline that is ibuprofen in which the isobutyl group is replaced by a (2-methylprop-2-en-1-yl)amino group. A non-steroidal anti-inflammatory drug, it is used for treatment of inflammatory and rheumatic disorders.

Manufacturing Process

Methyl 2-(p-aminophenyl)propionate:
Methyl 2-(p-nitrophenyl)acrylate (52 g) is hydrogenated in ethanol (500 ml) in the presence of 5% palladium-over-charcoal, while maintaining the temperature at +5°C. The theoretical amount of hydrogen is taken up within one hour. After separation of the catalyst and concentration to dryness, the resulting material gives methyl 2-(p-aminophenyl)proprionate which crystallizes: MP: = 40°-43°C.
Methyl 2-(p-methallylaminophenyl)propionate hydrochloride:
A mixture of methyl 2-(p-aminophenyl)propionate (44.75 g), methallyl chloride (34 g) and pyridine (30 ml) in isopropanol (400 ml) is boiled during 30 hours. The solvent is removed in vacuo and the residue is taken up into water and ether. After separation, the organic phase is washed repeatedly with water, after which it is dried and concentrated in vacuo. The resulting oil is fractionally distilled in vacuo (0.1 mm Hg; 5 g of oil essentially consisting of methyl 2-(p-aminophenyl)propionate are collected at 115°-120°C; 30 g of oil consisting of a mixture of mono- (80%) and disubstituted (20%) amines is collected at 128°-130°C. This oil is used to prepare the hydrochloride, which is recrystallized from ethyl acetate, to give white crystals (22.7 g) melting at 115°C. Saponification in the cold methanolic hydroxide gives the desired 2-(4- (methallylamino)phenyl)propionic acid (alminoprofen). MP: 120°C.

brand name

MINALFENE

Therapeutic Function

Analgesic, Antiinflammatory

alminoprofen Preparation Products And Raw materials

Raw materials

Preparation Products

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alminoprofen Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Shanghai Run-Biotech Co., Ltd.
Tel
021-57171705 13817537615
Fax
QQ3095748324
Email
sales@run-biotech.com
Country
China
ProdList
2402
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Xi'an NewProChem Co.,Ltd.
Tel
15332490153
Fax
QQ 2725398181
Email
newprochem@126.com
Country
China
ProdList
991
Advantage
55
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
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View Lastest Price from alminoprofen manufacturers

Career Henan Chemica Co
Product
alminoprofen 39718-89-3
Price
US $8.00/KG
Min. Order
1g
Purity
Min98% HPLC/gc
Supply Ability
g/kg/ton
Release date
2020-11-04
Dideu Industries Group Limited
Product
alminoprofen 39718-89-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-15

39718-89-3, alminoprofenRelated Search:


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  • ALMINOPROFEN(FORR&DONLY)
  • EB 382
  • Minalfene
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  • 2-(4-((2-Methylallyl)amino)phenyl)propansaeure
  • 4-((2-Methylallyl)amino)hydratropasaeure
  • Acide (methallylamino-4 phenyl)-2 propionique
  • Acide (methallylamino-4 phenyl)-2 propionique [french]
  • Alminoprofene
  • Alminoprofene [inn-french]
  • Alminoprofeno
  • rac AlMinoprofen
  • α-Methyl-4-[(2-Methyl-2-propen-1-yl)aMino]benzeneacetic Acid
  • 2-(4-((2-Methylallyl)aMino)phenyl)propanoic acid
  • Benzeneacetic acid, α-methyl-4-[(2-methyl-2-propen-1-yl)amino]-
  • alminoprofen USP/EP/BP
  • AlminoprofenQ: What is Alminoprofen Q: What is the CAS Number of Alminoprofen Q: What is the storage condition of Alminoprofen Q: What are the applications of Alminoprofen
  • Alminoprofen CAS NO.39718-89-3
  • 39718-89-3