alminoprofen

Product Name: alminoprofen
CAS No.: 39718-89-3
Chemical Name: alminoprofen
Synonyms: EB 382;Minalfen;Minalfene;alminoprofen;Alminoprofene;Alminoprofeno;rac AlMinoprofen;alminoprofen USP/EP/BP;ALMINOPROFEN(FORR&DONLY);Alminoprofene [inn-french]
CBNumber: CB7885929
Molecular Formula: C13H17NO2
Formula Weight: 219.28
MOL File: 39718-89-3.mol

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alminoprofen Property

Melting point:: 107°
Boiling point:: 360.1°C (rough estimate)
Density: 1.0697 (rough estimate)
refractive index: 1.5100 (estimate)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.86±0.50(Predicted)
color: Light Brown

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Safety

Toxicity: LD50 orally in mice: 2400 mg/kg (Dumaitre)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A575150
Product name: racAlminoprofen
Packaging: 1g
Price: $790
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003395
Product name: ALMINOPROFEN
Purity: 95.00%
Packaging: 1G
Price: $1575
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003395
Product name: ALMINOPROFEN
Purity: 95.00%
Packaging: 2.5G
Price: $2255
Updated: 2021/12/16

ChemScene

Product number: CS-0009220
Product name: Alminoprofen
Purity: 99.35%
Packaging: 100mg
Price: $275
Updated: 2021/12/16

ChemScene

Product number: CS-0009220
Product name: Alminoprofen
Purity: 99.35%
Packaging: 250mg
Price: $450
Updated: 2021/12/16

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alminoprofen Chemical Properties,Usage,Production

Description

Alminoprofen is an arylpropionic acid analgesic/antiinflammatory agent indicated for the short term management of dental, traumatic and postpartum pain.

Originator

Labs. Dr. E. Bouchara (France)

Uses

Alminoprofen is a nonsteroidal antiinflammatory drugs (NSAID) of the phenylpropionic acid class. Alminoprofen maybe a useful therapeutic option in the management of immune dysfunction in rheumatoid ar thritis.

Definition

ChEBI: A substituted aniline that is ibuprofen in which the isobutyl group is replaced by a (2-methylprop-2-en-1-yl)amino group. A non-steroidal anti-inflammatory drug, it is used for treatment of inflammatory and rheumatic disorders.

Manufacturing Process

Methyl 2-(p-aminophenyl)propionate:
Methyl 2-(p-nitrophenyl)acrylate (52 g) is hydrogenated in ethanol (500 ml) in the presence of 5% palladium-over-charcoal, while maintaining the temperature at +5°C. The theoretical amount of hydrogen is taken up within one hour. After separation of the catalyst and concentration to dryness, the resulting material gives methyl 2-(p-aminophenyl)proprionate which crystallizes: MP: = 40°-43°C.
Methyl 2-(p-methallylaminophenyl)propionate hydrochloride:
A mixture of methyl 2-(p-aminophenyl)propionate (44.75 g), methallyl chloride (34 g) and pyridine (30 ml) in isopropanol (400 ml) is boiled during 30 hours. The solvent is removed in vacuo and the residue is taken up into water and ether. After separation, the organic phase is washed repeatedly with water, after which it is dried and concentrated in vacuo. The resulting oil is fractionally distilled in vacuo (0.1 mm Hg; 5 g of oil essentially consisting of methyl 2-(p-aminophenyl)propionate are collected at 115°-120°C; 30 g of oil consisting of a mixture of mono- (80%) and disubstituted (20%) amines is collected at 128°-130°C. This oil is used to prepare the hydrochloride, which is recrystallized from ethyl acetate, to give white crystals (22.7 g) melting at 115°C. Saponification in the cold methanolic hydroxide gives the desired 2-(4- (methallylamino)phenyl)propionic acid (alminoprofen). MP: 120°C.

brand name

MINALFENE

Therapeutic Function

Analgesic, Antiinflammatory

alminoprofen Preparation Products And Raw materials

Raw materials

Preparation Products

Aminoprofen

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alminoprofen Suppliers

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View Lastest Price from alminoprofen manufacturers

Career Henan Chemica Co

Product: alminoprofen 39718-89-3
Price: US $8.00/KG
Min. Order: 1g
Purity: Min98% HPLC/gc
Supply Ability: g/kg/ton
Release date: 2020-11-04

Dideu Industries Group Limited

Product: alminoprofen 39718-89-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-15

39718-89-3, alminoprofenRelated Search:

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alminoprofen USP/EP/BP

AlminoprofenQ: What is Alminoprofen Q: What is the CAS Number of Alminoprofen Q: What is the storage condition of Alminoprofen Q: What are the applications of Alminoprofen

Alminoprofen CAS NO.39718-89-3

39718-89-3