1-butylbiguanide
- Product Name
- 1-butylbiguanide
- CAS No.
- 692-13-7
- Chemical Name
- 1-butylbiguanide
- Synonyms
- Buformin;DBV;W 37;H 224;Glybigid;Butformin;Buformine;Dibetos B;Butyldiguanide;Butylbiguanide
- CBNumber
- CB7913312
- Molecular Formula
- C6H15N5
- Formula Weight
- 157.2168
- MOL File
- 692-13-7.mol
1-butylbiguanide Property
- Melting point:
- 174-176 °C
- Boiling point:
- 271.89°C (rough estimate)
- Density
- 1.0291 (rough estimate)
- refractive index
- 1.8070 (estimate)
- pka
- 12.27±0.10(Predicted)
- InChI
- InChI=1S/C6H15N5/c1-2-3-4-10-6(9)11-5(7)8/h2-4H2,1H3,(H6,7,8,9,10,11)
- InChIKey
- XSEUMFJMFFMCIU-UHFFFAOYSA-N
- SMILES
- C(=N)(NCCCC)NC(=N)N
N-Bromosuccinimide Price
- Product number
- API0000433
- Product name
- BUFORMIN
- Purity
- 95.00%
- Packaging
- 0.5G
- Price
- $675
- Updated
- 2021/12/16
- Product number
- 7887
- Product name
- Buformin
- Packaging
- 100mg
- Price
- $875
- Updated
- 2021/12/16
- Product number
- API0000433
- Product name
- BUFORMIN
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1819.13
- Updated
- 2021/12/16
- Product number
- 7887
- Product name
- Buformin
- Packaging
- 0.5g
- Price
- $2000
- Updated
- 2021/12/16
1-butylbiguanide Chemical Properties,Usage,Production
Uses
Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase
Definition
ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.
brand name
Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.
World Health Organization (WHO)
Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)
in vivo
Buformin (oral administation; 7.6?mmol/kg of chow; 7 days) exhibits significantly reduced tumor volumes and weights, and?hinders mammary morphogenesis and proliferation in MMTV-erbB-2 transgenic mice[1]
| Animal Model: | Female MMTV-erbB-2 transgenic mice[1] |
| Dosage: | 7.6?mmol/kg |
| Administration: | Oral administation; 7 days |
| Result: | Inhibited mammary syngeneic tumor growth in MMTV-erbB-2 transgenic mice. |
1-butylbiguanide Preparation Products And Raw materials
Raw materials
Preparation Products
1-butylbiguanide Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71