1-butylbiguanide

Product Name: 1-butylbiguanide
CAS No.: 692-13-7
Chemical Name: 1-butylbiguanide
Synonyms: Buformin;DBV;W 37;H 224;Glybigid;Butformin;Buformine;Dibetos B;Butyldiguanide;Butylbiguanide
CBNumber: CB7913312
Molecular Formula: C6H15N5
Formula Weight: 157.2168
MOL File: 692-13-7.mol

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1-butylbiguanide Property

Melting point:: 174-176 °C
Boiling point:: 271.89°C (rough estimate)
Density: 1.0291 (rough estimate)
refractive index: 1.8070 (estimate)
pka: 12.27±0.10(Predicted)
InChI: InChI=1S/C6H15N5/c1-2-3-4-10-6(9)11-5(7)8/h2-4H2,1H3,(H6,7,8,9,10,11)
InChIKey: XSEUMFJMFFMCIU-UHFFFAOYSA-N
SMILES: C(=N)(NCCCC)NC(=N)N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0000433
Product name: BUFORMIN
Purity: 95.00%
Packaging: 0.5G
Price: $675
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 7887
Product name: Buformin
Packaging: 100mg
Price: $875
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0000433
Product name: BUFORMIN
Purity: 95.00%
Packaging: 1G
Price: $1819.13
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 7887
Product name: Buformin
Packaging: 0.5g
Price: $2000
Updated: 2021/12/16

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1-butylbiguanide Chemical Properties,Usage,Production

Uses

Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase

Definition

ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.

brand name

Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.

World Health Organization (WHO)

Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)

in vivo

Buformin (oral administation; 7.6?mmol/kg of chow; 7 days) exhibits significantly reduced tumor volumes and weights, and?hinders mammary morphogenesis and proliferation in MMTV-erbB-2 transgenic mice^[1]

Animal Model:	Female MMTV-erbB-2 transgenic mice^[1]
Dosage:	7.6?mmol/kg
Administration:	Oral administation; 7 days
Result:	Inhibited mammary syngeneic tumor growth in MMTV-erbB-2 transgenic mice.

1-butylbiguanide Preparation Products And Raw materials

Raw materials

Preparation Products

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1-butylbiguanide Suppliers

Canada 1 China 20 India 2 United States 6 Global 29

Chengdu Kaitaichuang Pharmaceutical Technology Co., Ltd

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692-13-7, 1-butylbiguanideRelated Search:

Chlorhexidine Diacetate ALEXIDINE DIHYDROCHLORIDE Chlorhexidine digluconate Chlorhexidine Chlorhexidine hydrochloride BuforMin Hydrochloride 1-butylbiguanide Chlorhexidine diacetate Poly(hexamethylenebiguanide) Etoformin N-((p-Chlorophenyl)amidino)-4-methyl-1-piperidinecarboxamidine monohyd rochloride 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2(1H)-ONE HYDRAZONE 1-cyclohexylbiguanide monohydrochloride BPC 151 chlorhexidine phosphanilate N-((p-Chlorophenyl)amidino)-1-piperidinecarboxamidine hydrochloride CHLORHEXIDINE-RING-UL-14C DIHYDROCHLORIDE CHLORHEXIDINE-RING-UL-14C DIGLUCONATE

N-BUTYLBIGUANIDINE

Buformin

Buformin (base and/or unspecified salts)

Buformine

Butformin

Butylbiguanide

Butyldiguanide

DBV

Dibetos B

Glybigid

H 224

N1-Butylbiguanide

N-Butyl-idodicarbonimidic Diamide

W 37

1-butylbiguanide

1-[bis(azanyl)methylidene]-2-butyl-guanidine

2-butyl-1-(diaminomethylene)guanidine

2-butyl-1-(diaminomethylidene)guanidine

Imidodicarbonimidicdiamide, N-butyl-

1-butylbiguanide USP/EP/BP

N-butylimidodicarbonimidic DiamideDiscontinued, see B689520

692-13-7

500-20-3

C6H15N5

Intermediates & Fine Chemicals

Pharmaceuticals