1-Methyl-1,2,3-triazole

Product Name: 1-Methyl-1,2,3-triazole
CAS No.: 16681-65-5
Chemical Name: 1-Methyl-1,2,3-triazole
Synonyms: 1-Methyl-1;NISTC16681655;methyltriazole;1-Methyl-1,2,3-triazole;1H-1,2,3-Triazole, 1-methyl-;1-Methyl-1,2,3-triazole CAS:16681-65-5
CBNumber: CB7946963
Molecular Formula: C3H5N3
Formula Weight: 83.09
MOL File: 16681-65-5.mol

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1-Methyl-1,2,3-triazole Property

Boiling point:: 223-225 °C
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 1.40±0.10(Predicted)
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C3H5N3/c1-6-3-2-4-5-6/h2-3H,1H3
InChIKey: JWAWEQBUZOGIBZ-UHFFFAOYSA-N
SMILES: N1(C)C=CN=N1

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M330605
Product name: 1-Methyl-1,2,3-triazole
Packaging: 1g
Price: $140
Updated: 2021/12/16

AK Scientific

Product number: Y7754
Product name: 1-Methyl-1H-1,2,3-triazole
Packaging: 5g
Price: $167
Updated: 2021/12/16

AK Scientific

Product number: Y7754
Product name: 1-Methyl-1H-1,2,3-triazole
Packaging: 1g
Price: $52
Updated: 2021/12/16

Matrix Scientific

Product number: 058087
Product name: 1-Methyl-1,2,3-triazole
Purity: 95%
Packaging: 1g
Price: $89
Updated: 2021/12/16

AK Scientific

Product number: J96680
Product name: 1-Methyl-1H-1,2,3-triazole
Packaging: 25g
Price: $380
Updated: 2021/12/16

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1-Methyl-1,2,3-triazole Chemical Properties,Usage,Production

Uses

An azole compound used for binding affinity with various cytochrome P 450 (CYP) proteins.

Synthesis

288-36-8

74-88-4

16681-65-5

Step A: 1H-1,2,3-triazole (1.0 g, 14.5 mmol), iodomethane (3.1 g, 21.7 mmol), and potassium carbonate (4.0 g, 28.9 mmol) were dissolved in tetrahydrofuran (15 mL), and the reaction was stirred for 3 hours at room temperature. After the reaction was completed, ethyl acetate (20 mL) and water (10 mL) were added for extraction and the organic phase was separated. The organic phase was concentrated under reduced pressure to remove the solvent to obtain the crude product. The crude product was purified by silica gel column chromatography with 10% methanol/dichloromethane as eluent to afford 1-methyl-1H-1,2,3-triazole (860 mg, 10.4 mmol, 71% yield) as a yellow oil.

References

[1] Crystal Growth and Design, 2015, vol. 15, # 2, p. 752 - 758
[2] Chemistry - A European Journal, 2017, vol. 23, # 71, p. 17870 - 17873
[3] Patent: WO2015/142903, 2015, A2. Location in patent: Page/Page column 102
[4] Patent: WO2015/140133, 2015, A1. Location in patent: Page/Page column 115
[5] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 6, p. 650 - 654

1-Methyl-1,2,3-triazole Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methyl-1,2,3-triazole Suppliers

China 105 India 1 United Kingdom 1 United States 11 Global 118

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View Lastest Price from 1-Methyl-1,2,3-triazole manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: 1-Methyl-1,2,3-triazole 16681-65-5
Price: US $95.00-950.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-13

Career Henan Chemical Co

Product: 1-Methyl-1,2,3-triazole 16681-65-5
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: ask
Release date: 2020-01-08

16681-65-5, 1-Methyl-1,2,3-triazoleRelated Search:

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1-Methyl-1,2,3-triazole

NISTC16681655

1H-1,2,3-Triazole, 1-methyl-

1-Methyl-1

1-Methyl-1,2,3-triazole CAS:16681-65-5

methyltriazole

16681-65-5