ChemicalBook > CAS DataBase List > 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER

2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER

Product Name
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.
4815-29-6
Chemical Name
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms
AKOS 92578;AKOS B000470;AKOS BBB/009;AKOS MSC-0428;AKOS BBS-00004585;BUTTPARK 96\57-70;IFLAB-BB F1386-0049;OTAVA-BB BB0125160050;4H-CYCLOPENTA[B]THIOPHENE;ETHYL 2-AMINOCYCLOPENTA[B]THIOPHENE-3-CARBOXYLATE
CBNumber
CB8100515
Molecular Formula
C10H13NO2S
Formula Weight
211.28
MOL File
4815-29-6.mol
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2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Property

Melting point:
90-94 °C
Boiling point:
386.8±42.0 °C(Predicted)
Density 
1.2079 (rough estimate)
refractive index 
1.6800 (estimate)
storage temp. 
2-8°C(protect from light)
pka
0.53±0.20(Predicted)
Appearance
Off-white to yellow Solid
InChI
InChI=1S/C10H13NO2S/c1-2-13-10(12)8-6-4-3-5-7(6)14-9(8)11/h2-5,11H2,1H3
InChIKey
BOJXCJDYZJSPMZ-UHFFFAOYSA-N
SMILES
C12CCCC=1C(C(OCC)=O)=C(N)S2
CAS DataBase Reference
4815-29-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/22-36/37/38
Safety Statements 
22-36/37/39-26
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R432431
Product name
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA(B)THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
Purity
AldrichCPR
Packaging
50MG
Price
$113
Updated
2025/07/31
TRC
Product number
E899470
Product name
Ethyl2-amino-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate
Packaging
250mg
Price
$55
Updated
2021/12/16
AK Scientific
Product number
X0324
Product name
Ethyl2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
Packaging
5g
Price
$67
Updated
2021/12/16
Oakwood
Product number
021473
Product name
2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylicacidethylester
Purity
96%
Packaging
5g
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
023865
Product name
Ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]-thiophene-3-carboxylate
Packaging
500mg
Price
$10
Updated
2021/12/16
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2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

light yellow to beige-brown crystalline powder

Synthesis

120-92-3

105-56-6

4815-29-6

GENERAL METHOD: Cyclopentanone (1.06 mL, 10 mmol), ethyl cyanoacetate (1.15 mL, 10 mmol), morpholine (0.90 mL, 10 mmol), and sulfur powder (0.32 g, 10 mmol) were dissolved in ethanol (10 mL) with stirring and refluxed overnight. Upon completion of the reaction, the reaction mixture was cooled to room temperature and the solvent was subsequently removed under vacuum. The crude product was washed with cold ethanol, filtered through a sintered funnel and dried under vacuum. The dried crude product was dissolved in dichloromethane and washed with brine. The organic layer was separated and concentrated under low vacuum to afford the target compound ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (2a), yield: 73% (1.83 g).

References

[1] Synthetic Communications, 2010, vol. 40, # 14, p. 2067 - 2074
[2] Journal of Sulfur Chemistry, 2014, vol. 35, # 3, p. 261 - 269
[3] Chemical Communications, 2018, vol. 54, # 81, p. 11411 - 11414
[4] Archiv der Pharmazie, 2018, vol. 351, # 5,
[5] Journal of Medicinal Chemistry, 2002, vol. 45, # 2, p. 382 - 389

2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Sulfur Piperidine Cyclopentanone Ethyl cyanoacetate

Preparation Products

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2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

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View Lastest Price from 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLICACIDETHYLESTER 4815-29-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
g/kg/T
Release date
2019-12-18

4815-29-6, 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTERRelated Search:

2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl thiophene-3-carboxylate 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER AURORA 2791 AURORA 1211 AURORA 2485 2-(3-CARBOXY-ACRYLOYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER AURORA 4112 AURORA 3721 AURORA 6336 AURORA 4280 AURORA 417 AURORA 3574 2-(3-CARBOXY-PROPIONYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER AURORA 1321 AURORA 2786 AURORA 3575 AURORA 2486

  • Ethyl 2-aminocyclopenta[b]thiophene-3-carboxylate, 99+%
  • BUTTPARK 96\57-70
  • IFLAB-BB F1386-0049
  • ETHYL 2-AMINOCYCLOPENTA[B]THIOPHENE-3-CARBOXYLATE
  • ETHYL 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLATE
  • 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
  • 4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID, 2-AMINO-5,6-DIHYDRO-, ETHYL ESTER
  • AKOS B000470
  • AKOS 92578
  • AKOS MSC-0428
  • AKOS BBS-00004585
  • AKOS BBB/009
  • OTAVA-BB BB0125160050
  • 2-AMINO-5,6-DIHYDRO-4-[4H]-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
  • 2-amino-2H-cyclopenta[b]thiophene-3-carboxylic acid ethyl ester
  • ethyl 2-amino-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate
  • Ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate ,98%
  • 2-amino-5,6-dihydro-4H-cyclopenta[d]thiophene-3-carboxylic acid ethyl ester
  • 2-Amino-cyclopentano-[b]-thiophen-3-carbonsaeureethylester
  • ETHYL 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLAT
  • 4H-CYCLOPENTA[B]THIOPHENE
  • ethyl 2-amino-5,6-dihydro-4H-cyclopenta[d]thiophene-3-carboxylate
  • Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-car
  • 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
  • Ethyl 2-amino-5,6-dihydro-4h-cyclopenta[b]thiophene-3-carboxylic acid
  • 4815-29-6
  • Thiophene