2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
- Product Name
- 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
- CAS No.
- 4815-29-6
- Chemical Name
- 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
- Synonyms
- AKOS 92578;AKOS B000470;AKOS BBB/009;AKOS MSC-0428;AKOS BBS-00004585;BUTTPARK 96\57-70;IFLAB-BB F1386-0049;OTAVA-BB BB0125160050;4H-CYCLOPENTA[B]THIOPHENE;ETHYL 2-AMINOCYCLOPENTA[B]THIOPHENE-3-CARBOXYLATE
- CBNumber
- CB8100515
- Molecular Formula
- C10H13NO2S
- Formula Weight
- 211.28
- MOL File
- 4815-29-6.mol
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Property
- Melting point:
- 90-94 °C
- Boiling point:
- 386.8±42.0 °C(Predicted)
- Density
- 1.2079 (rough estimate)
- refractive index
- 1.6800 (estimate)
- storage temp.
- 2-8°C(protect from light)
- pka
- 0.53±0.20(Predicted)
- Appearance
- Off-white to yellow Solid
- InChI
- InChI=1S/C10H13NO2S/c1-2-13-10(12)8-6-4-3-5-7(6)14-9(8)11/h2-5,11H2,1H3
- InChIKey
- BOJXCJDYZJSPMZ-UHFFFAOYSA-N
- SMILES
- C12CCCC=1C(C(OCC)=O)=C(N)S2
- CAS DataBase Reference
- 4815-29-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/22-36/37/38
- Safety Statements
- 22-36/37/39-26
- HazardClass
- IRRITANT
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- R432431
- Product name
- 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA(B)THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $113
- Updated
- 2025/07/31
- Product number
- E899470
- Product name
- Ethyl2-amino-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylate
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- X0324
- Product name
- Ethyl2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
- Packaging
- 5g
- Price
- $67
- Updated
- 2021/12/16
- Product number
- 021473
- Product name
- 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylicacidethylester
- Purity
- 96%
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 023865
- Product name
- Ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]-thiophene-3-carboxylate
- Packaging
- 500mg
- Price
- $10
- Updated
- 2021/12/16
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Chemical Properties
light yellow to beige-brown crystalline powder
Synthesis
120-92-3
105-56-6
4815-29-6
GENERAL METHOD: Cyclopentanone (1.06 mL, 10 mmol), ethyl cyanoacetate (1.15 mL, 10 mmol), morpholine (0.90 mL, 10 mmol), and sulfur powder (0.32 g, 10 mmol) were dissolved in ethanol (10 mL) with stirring and refluxed overnight. Upon completion of the reaction, the reaction mixture was cooled to room temperature and the solvent was subsequently removed under vacuum. The crude product was washed with cold ethanol, filtered through a sintered funnel and dried under vacuum. The dried crude product was dissolved in dichloromethane and washed with brine. The organic layer was separated and concentrated under low vacuum to afford the target compound ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (2a), yield: 73% (1.83 g).
References
[1] Synthetic Communications, 2010, vol. 40, # 14, p. 2067 - 2074
[2] Journal of Sulfur Chemistry, 2014, vol. 35, # 3, p. 261 - 269
[3] Chemical Communications, 2018, vol. 54, # 81, p. 11411 - 11414
[4] Archiv der Pharmazie, 2018, vol. 351, # 5,
[5] Journal of Medicinal Chemistry, 2002, vol. 45, # 2, p. 382 - 389
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers
- Tel
- --
- Fax
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- reag-info@gms.kanto.co.jp
- Country
- Japan
- ProdList
- 6756
- Advantage
- 74
View Lastest Price from 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers
- Product
- 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLICACIDETHYLESTER 4815-29-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- g/kg/T
- Release date
- 2019-12-18