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(+)-PINORESINOL

Product Name
(+)-PINORESINOL
CAS No.
487-36-5
Chemical Name
(+)-PINORESINOL
Synonyms
80% ee);(+)-Piresil;(+)-PINORESINOL;(+)-Pinoresinol (>(+)-Pinoresinol (>80% ee);(+)-Pinoresinol,Pinoresinol;(1β,5β)-2β,6β-Bis(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane;4,4′-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol);4,4'-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol);4,4'-[(1R,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl] Bis(2-methoxyphenol)
CBNumber
CB8100858
Molecular Formula
C20H22O6
Formula Weight
358.39
MOL File
487-36-5.mol
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(+)-PINORESINOL Property

Melting point:
112 °C
Boiling point:
556.5±50.0 °C(Predicted)
Density 
1.385 g/cm3
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: ≥6mg/mL
pka
9.54±0.35(Predicted)
form 
Solid
color 
white to tan
LogP
1.591 (est)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
40674
Product name
Pinoresinol
Purity
≥95.0% (HPLC)
Packaging
10mg
Price
$419
Updated
2024/03/01
Sigma-Aldrich
Product number
06709
Product name
Pinoresinol
Purity
analyticalstandard
Packaging
10mg
Price
$631
Updated
2024/03/01
Cayman Chemical
Product number
27700
Product name
(+)-Pinoresinol
Packaging
5mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
27700
Product name
(+)-Pinoresinol
Packaging
10mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
27700
Product name
(+)-Pinoresinol
Packaging
25mg
Price
$208
Updated
2024/03/01
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(+)-PINORESINOL Chemical Properties,Usage,Production

Description

(+)-Pinoresinol is a lignan that has been found in Forsythia and virgin olive oils and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase (IC50s = 492 and 34.3 μM in Baker’s yeast and rat small intestine, respectively). (+)-Pinoresinol scavenges ABTS , but not 2,2-diphenyl-1-picrylhydrazyl (DPPH; ), radicals in cell-free assays (IC50s = 13.43 and >200 μg/ml, respectively). It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37, cells with IC50 values of 29.35, 62.35, 75.32, >80, and >80 μM, respectively. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells (EC50 = 6.96 μM) and inhibits LPS-induced nitric oxide production in RAW 264.7 cells (IC50 = 7.89 μM).

Uses

(+)-Pinoresinol is a lignan found in olive oil and in other plants. This phenolic compound was reported to have antioxidant and anticancer potential.

Definition

ChEBI: An enantiomer of pinoresinol having (+)-1S,3aR,4S,6aR-configuration.

(+)-PINORESINOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-PINORESINOL Suppliers

China 107 Finland 1 Germany 1 India 1 Japan 1 United Kingdom 2 United States 11 Global 124
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from (+)-PINORESINOL manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Pinoresinol 487-36-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-08
Career Henan Chemical Co
Product
(+)-PINORESINOL 487-36-5
Price
US $8.00/KG
Min. Order
1KG
Purity
＞98% HPLC
Supply Ability
20 tons
Release date
2020-02-17

487-36-5, (+)-PINORESINOLRelated Search:

galgravin MAGNOFLORINE IODIDE, (+)-(RG) PINORESINOL DIGLUCOSIDE(P)(PLEASE CALL),PINORESINOL DIGLUCOPYRANOSIDE(P),PINORESINOL DIGLUCOPYRANOSIDE(P)(Please Call) Sesamin ELEUTHEROSIDE E1 magnolin (+)-PINORESINOL (+)-Pinoresinol dimethyl ether,Pinoresinol dimethyl ether (+)-1-epi-Pinoresinol pinoresinol reductase PINORESINOL DIGLUCOPYRANOSIDE,PINORESINOL (-)-PINORESINOL (+)-Syringaresinol d-Pinoresinol (+)-Pinoresinol-di-O-β-D-glucoside,(+)-Pinoresinol 4,4'-O-di-β-D-glucopyranoside,PINORESINOL DIGLUCOSIDE Pinoresinol, Di-Acetate (+)-Pinoresinol-4'-O-β-D-glucoside,(+)-Pinoresinol O-β-D-glucopyranoside,(+)-Pinoresinol-O-β-D-glucoside (1S,3AR,4S,6AR)-1,4-BIS(3,4-DIMETHOXYPHENYL)-HEXAHYDROFURO[3,4-C]FURAN

  • (+)-PINORESINOL
  • (-)-4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol)
  • (3aS,6aS)-3a,4,6,6a-Tetrahydro-3β,6β-bis(4-hydroxy-3-methoxyphenyl)-1H,3H-furo[3,4-c]furan
  • (3R,3aβ,6aβ)-3β,6β-Bis(3-methoxy-4-hydroxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
  • 2-Methoxy-4-[(1R)-4α-(3-methoxy-4-hydroxyphenyl)-3aα,4,6,6aα-tetrahydro-1H,3H-furo[3,4-c]furan-1α-yl]phenol
  • 4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol)
  • (1S)-1β,4β-Bis(4-hydroxy-3-methoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan
  • (1β,5β)-2β,6β-Bis(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
  • 4,4'-[(3aα,4,6,6aα-Tetrahydro-1H,3H-furo[3,4-c]furan)-3α,6α-diyl]bis(2-methoxyphenol)
  • 4,4'-[(3S)-3aα,4,6,6aα-Tetrahydro-1H,3H-furo[3,4-c]furan-3α,6α-diyl]bis(2-methoxyphenol)
  • (+)-Piresil
  • Phenol,4,4'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-Methoxy-
  • 4,4′-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol)
  • 4,4′-[(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxyphenol)
  • (+)-Pinoresinol,Pinoresinol
  • 80% ee)
  • (+)-Pinoresinol (&gt
  • 4,4'-[(1R,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl] Bis(2-methoxyphenol)
  • 4-[(1S,3aR,4S,6aR)-4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenol
  • (+)-Pinoresinol (>80% ee)
  • apoptotic,sensitizer,Pinoresinol,caterpillar,inhibit,cancer,Apoptosis,Inhibitor,lignol,glioblastoma
  • 4,4'-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol)
  • 487-36-5
  • Miscellaneous Natural Products