ChemicalBook > CAS DataBase List > MELPERONE

MELPERONE

Product Name
MELPERONE
CAS No.
3575-80-2
Chemical Name
MELPERONE
Synonyms
FG 5111;Buronil;Melperon;metylperon;Flubuperone;Melperone >Melperone,Inhibitor,inhibit;Melperone (base and/or unspecified salts);4-Fluoro-γ-(4-Methylpiperidino)butyrophenone;γ-(4-Methylpiperidino)-p-fluorobutyrophenone
CBNumber
CB81011889
Molecular Formula
C16H22FNO
Formula Weight
263.35
MOL File
3575-80-2.mol
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MELPERONE Property

Melting point:
78.0 to 82.0 °C
Boiling point:
bp0.1 120-125°
Density 
1.046±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 41.67 mg/mL (158.23 mM)
pka
9.34±0.10(Predicted)
form 
powder to crystal
color 
White to Light yellow to Light orange
Merck 
14,5827
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Safety

HS Code 
2933.39.3100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2622
Product name
Melperone
Purity
>95.0%(GC)
Packaging
25mg
Price
$116
Updated
2024/03/01
TCI Chemical
Product number
M2622
Product name
Melperone
Purity
>95.0%(GC)
Packaging
100mg
Price
$338
Updated
2024/03/01
Chem-Impex
Product number
38067
Product name
Melperone,95%(GC)
Purity
95%(GC)
Packaging
25MG
Price
$123.2
Updated
2021/12/16
AK Scientific
Product number
E830
Product name
Melperone
Packaging
25mg
Price
$212
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008708
Product name
MELPERONE
Purity
95.00%
Packaging
100MG
Price
$237.3
Updated
2021/12/16
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MELPERONE Chemical Properties,Usage,Production

Originator

Eunerpan,Nordmark,W. Germany,1965

Definition

ChEBI: 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone is an aromatic ketone.

Manufacturing Process

A solution or dispersion consisting of 20.1 g (0.1 mol) of γ-chloro-pfluorobutyrophenone, 19.8 g (0.2 mol) of 4-methylpiperidine and 0.1 g of potassium iodide in 150 ml toluene is heated in a sealed glass tube for 15 hours at 100°C to 110°C. The potassium iodide and the 4-methylpiperidine hydrochloride formed in the reaction are separated by filtration and the solvent removed from the filtrate by evaporation in vacuum on a steam bath. The residue is distilled and the fraction obtained at 120°C to 125°C and at a pressure lower than 0.1 mm Hg is collected. The base is dissolved in ether and the 4-fluoro-γ-(4-methylpiperidino)-butyrophenone precipitated as the hydrochloride. The reaction product is purified by recrystallization in ethanol/ether.
Yield 22.0 g (73% of theory). MP 209°C to 211°C.

Therapeutic Function

Neuroleptic

MELPERONE Preparation Products And Raw materials

Raw materials

Preparation Products

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MELPERONE Suppliers

TCI (Shanghai) Development Co., Ltd.
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Sales-CN@TCIchemicals.com
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China
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Chemsky (shanghai) International Co.,Ltd
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Amatek Scientific Co. Ltd.
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Shanghai Xingui Biotechnology Co., Ltd.
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17501653713
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Shanghai HuanChuan Industry Co.,Ltd.
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021-61478794
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China
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Changzhou Hopschain Chemical Co.,Ltd.
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Amadis Chemical Company Limited
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ShenZhen Dieckmann Bio-Pharm Co.,LTD
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Shandong Ono Chemical Co., Ltd.
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Nextpeptide Inc
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AFINE CHEMICALS LIMITED
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Career Henan Chemica Co
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Shaanxi Dideu Medichem Co. Ltd
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Beijing Jin Ming Biotechnology Co., Ltd.
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Bide Pharmatech Ltd.
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InvivoChem
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Changzhou Bojia Biomedical Technology Co., Ltd.
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TargetMol Chemicals Inc.
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LGC Science (Shanghai) Ltd.
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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Wuhan WinYuanBei Trading Company
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XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Shanghai New Union Textra Import & Export Co., Ltd
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View Lastest Price from MELPERONE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Melperone 3575-80-2
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-19

3575-80-2, MELPERONERelated Search:


  • metylperon
  • Melperone (base and/or unspecified salts)
  • 1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)-1-butanone
  • Melperon
  • 1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one
  • 1-(4-Fluorophenyl)-4-(4-Methyl-1-piperidinyl)-1-butanone
  • 4'-Fluoro-4-(4-Methylpiperidino)butyrophenone
  • 4-Fluoro-γ-(4-Methylpiperidino)butyrophenone
  • Buronil
  • FG 5111
  • Flubuperone
  • γ-(4-Methylpiperidino)-p-fluorobutyrophenone
  • Melperone &gt
  • 1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-
  • Melperone,Inhibitor,inhibit
  • 3575-80-2
  • C16H22FNO