MELPERONE
- Product Name
- MELPERONE
- CAS No.
- 3575-80-2
- Chemical Name
- MELPERONE
- Synonyms
- FG 5111;Buronil;Melperon;metylperon;Flubuperone;Melperone >Melperone,Inhibitor,inhibit;Melperone (base and/or unspecified salts);4-Fluoro-γ-(4-Methylpiperidino)butyrophenone;γ-(4-Methylpiperidino)-p-fluorobutyrophenone
- CBNumber
- CB81011889
- Molecular Formula
- C16H22FNO
- Formula Weight
- 263.35
- MOL File
- 3575-80-2.mol
MELPERONE Property
- Melting point:
- 78.0 to 82.0 °C
- Boiling point:
- bp0.1 120-125°
- Density
- 1.046±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 41.67 mg/mL (158.23 mM)
- pka
- 9.34±0.10(Predicted)
- form
- powder to crystal
- color
- White to Light yellow to Light orange
- Merck
- 14,5827
Safety
- HS Code
- 2933.39.3100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M2622
- Product name
- Melperone
- Purity
- >95.0%(GC)
- Packaging
- 25mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- M2622
- Product name
- Melperone
- Purity
- >95.0%(GC)
- Packaging
- 100mg
- Price
- $338
- Updated
- 2024/03/01
- Product number
- 38067
- Product name
- Melperone,95%(GC)
- Purity
- 95%(GC)
- Packaging
- 25MG
- Price
- $123.2
- Updated
- 2021/12/16
- Product number
- E830
- Product name
- Melperone
- Packaging
- 25mg
- Price
- $212
- Updated
- 2021/12/16
- Product number
- API0008708
- Product name
- MELPERONE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $237.3
- Updated
- 2021/12/16
MELPERONE Chemical Properties,Usage,Production
Originator
Eunerpan,Nordmark,W. Germany,1965
Definition
ChEBI: 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone is an aromatic ketone.
Manufacturing Process
A solution or dispersion consisting of 20.1 g (0.1 mol) of γ-chloro-pfluorobutyrophenone, 19.8 g (0.2 mol) of 4-methylpiperidine and 0.1 g of potassium iodide in 150 ml toluene is heated in a sealed glass tube for 15 hours at 100°C to 110°C. The potassium iodide and the 4-methylpiperidine hydrochloride formed in the reaction are separated by filtration and the solvent removed from the filtrate by evaporation in vacuum on a steam bath. The residue is distilled and the fraction obtained at 120°C to 125°C and at a pressure lower than 0.1 mm Hg is collected. The base is dissolved in ether and the 4-fluoro-γ-(4-methylpiperidino)-butyrophenone precipitated as the hydrochloride. The reaction product is purified by recrystallization in ethanol/ether.
Yield 22.0 g (73% of theory). MP 209°C to 211°C.
Therapeutic Function
Neuroleptic
MELPERONE Preparation Products And Raw materials
Raw materials
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View Lastest Price from MELPERONE manufacturers
- Product
- Melperone 3575-80-2
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-19