ChemicalBook > CAS DataBase List > 1,3-Dioxo-2-isoindolineaceticacid

1,3-Dioxo-2-isoindolineaceticacid

Product Name
1,3-Dioxo-2-isoindolineaceticacid
CAS No.
6296-53-3
Chemical Name
1,3-Dioxo-2-isoindolineaceticacid
Synonyms
3-AcetaMidophthalic anhydride;N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetaMide;3-AcetylaMinophthalic Anhydride;NSC 17048;NSC 16261;1,3-Dioxo-2;Apremilast inter1;Apremilast Impurity 43;Apremilast Intermediates1;Apremilast Intermediate III
CBNumber
CB81073957
Molecular Formula
C10H7NO4
Formula Weight
205.17
MOL File
6296-53-3.mol
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1,3-Dioxo-2-isoindolineaceticacid Property

Melting point:
185-186℃
Boiling point:
489.1±28.0 °C(Predicted)
Density 
1.512±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol
form 
Solid
pka
13.81±0.20(Predicted)
color 
Off-White to Pale Yellow
Stability:
Moisture Sensitive
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Safety

HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2804
Product name
3-Acetamidophthalic Anhydride
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
A2804
Product name
3-Acetamidophthalic Anhydride
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$47
Updated
2024/03/01
TRC
Product number
A170980
Product name
3-AcetylaminophthalicAnhydride
Packaging
10g
Price
$1190
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0005999
Product name
N-(1,3-DIOXO-1,3-DIHYDRO-2-BENZOFURAN-4-YL)ACETAMIDE
Purity
95.00%
Packaging
5G
Price
$1212.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0005999
Product name
N-(1,3-DIOXO-1,3-DIHYDRO-2-BENZOFURAN-4-YL)ACETAMIDE
Purity
95.00%
Packaging
10G
Price
$1819.13
Updated
2021/12/16
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1,3-Dioxo-2-isoindolineaceticacid Chemical Properties,Usage,Production

Uses

3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2

1,3-Dioxo-2-isoindolineaceticacid Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-Dioxo-2-isoindolineaceticacid Suppliers

Americas 1 China 238 Europe 1 Germany 2 India 49 Japan 1 Switzerland 1 United Kingdom 2 United States 13 Global 308
Shanghai Mixiu Chemical Co., Ltd.
Tel
18101936766
Fax
021-58583907
Email
eileen@shmychem.com
Country
China
ProdList
351
Advantage
55
Zhongshan Haihong Medicine Co. Ltd
Tel
0760-86925768 18824993998
Fax
0760-86925770
Email
seas168@126.com
Country
China
ProdList
60
Advantage
58
Enantiotech Corporation Ltd
Tel
760-85282375 13212762451
Email
marketing@enantiotech.net
Country
China
ProdList
179
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
sales@zhiwe.net
Country
China
ProdList
578
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17989
Advantage
64
Changzhou Book Chemical Co., Ltd.
Tel
0519-68780180 13775119556
Fax
0519-68780180
Email
bookchem@126.com
Country
China
ProdList
552
Advantage
62
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
1004
Advantage
62
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View Lastest Price from 1,3-Dioxo-2-isoindolineaceticacid manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
1,3-Dioxo-2-isoindolineaceticacid 6296-53-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
≥1kg
Release date
2024-03-05
WUHAN FORTUNA CHEMICAL CO., LTD
Product
1,3-Dioxo-2-isoindolineaceticacid 6296-53-3
Price
US $0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
10kg/month
Release date
2021-12-17
Hangzhou ICH Biofarm Co., Ltd
Product
N-Phthaloylglycine 6296-53-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
≥1kg
Release date
2023-07-18

6296-53-3, 1,3-Dioxo-2-isoindolineaceticacidRelated Search:

Cyclohexanone Hydantoin (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine Apremilast Impurity E Apremilast Impurity 1 (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Apremilast Impurity 1/2 Apremilast Impurity 8 Apremilast Impurity 13 Apremilast Impurity 28 Apremilast Impurity 25 Apremilast-d8 (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide APST-ZA Apremilast Impurity 2 Apremilast Impurity 9 Apremilast impurity 18 Apremilast Impurity 15

  • N-(1,3-Dihydro-1,3-dioxoisobenzofuran-4-yl)acetamide
  • AcetaMide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-
  • 3-AcetylaMino-phthalsaeure-anhydrid
  • 3-AcetaMidophthalic anhydride
  • 1,3-Dioxo-2-isoindolineaceticacid CAS:6296-53-3
  • 3-AcetylaMinophthalic Anhydride
  • N-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetaMide
  • NSC 16261
  • NSC 17048
  • N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetaMide
  • N-(1,3-Dioxo-4-isobenzofuranyl)acetaMide
  • Apremilast Intermediate III
  • 3-Acetamidophthalic anhydride NSC 16261
  • N-(1,3-dioxo-2-benzofuran-4-yl)acetamide
  • N-(1,3-Dihydro-1,3-dioxo-4-isobenzofuranyl)acetamide
  • 1,3-Dioxo-2
  • RE-EXPORT OF REJECTED IMPORT MATERIAL: N -(1,3-DIHYDROIS OBENZOFURAN-4-YL) ACETAM IDE SYNONYM: 3-ACETAMIDOPHTHALIC ANHYDRI
  • Apremilast inter1
  • Apremilast Intermediates1
  • N-(1,3-Dioxo-1,3-dihydro-2- benzofuran-4-yl)acetamide Apremilast
  • N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)
  • Apremilast Impurity 43
  • 3-Aceta amido pthalic anhydride
  • 3-Acetamidophthalic Anhydride &gt
  • RSSYY(Perospirone Hydrochloride Hydrate)-7
  • 4-Acetamido-1,3-isobenzofurandione
  • 6296-53-3