3-O-Methylquercetin
- Product Name
- 3-O-Methylquercetin
- CAS No.
- 1486-70-0
- Chemical Name
- 3-O-Methylquercetin
- Synonyms
- NSC 154016;3-Methylquercetol;3-Methoxyluteolin;3-O-Methylquercetin;Rutoside Trihydrate Impurity 8;3',4',5,7-Tetrahydroxy-3-methoxyflavone;TETRAHYDROXY-3-METHOXYFLAVONE, 3',4',5,7-(RG);2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-chroMen-4-one;2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-1-benzopyran-4-one;2-(3,4-Dihydroxyphenyl)-3-methoxy-5,7-dihydroxy-4H-1-benzopyran-4-one
- CBNumber
- CB81075557
- Molecular Formula
- C16H12O7
- Formula Weight
- 316.26
- MOL File
- 1486-70-0.mol
3-O-Methylquercetin Property
- Melting point:
- 275 °C
- Boiling point:
- 643.0±55.0 °C(Predicted)
- Density
- 1.69±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- pka
- 6.31±0.40(Predicted)
- color
- Yellow
- BRN
- 324509
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C16H12O7/c1-22-16-14(21)13-11(20)5-8(17)6-12(13)23-15(16)7-2-3-9(18)10(19)4-7/h2-6,17-20H,1H3
- InChIKey
- WEPBGSIAWZTEJR-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1OC
- LogP
- 2.020 (est)
N-Bromosuccinimide Price
- Product number
- 90081
- Product name
- 3-O-Methylquercetin
- Purity
- ≥97% (HPLC)
- Packaging
- 1mg
- Price
- $302
- Updated
- 2025/07/31
- Product number
- 90081
- Product name
- 3-O-Methylquercetin
- Purity
- ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $735
- Updated
- 2025/07/31
- Product number
- M326545
- Product name
- 3-O-MethylQuercetin
- Packaging
- 25mg
- Price
- $950
- Updated
- 2021/12/16
- Product number
- 090947
- Product name
- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $1853
- Updated
- 2021/12/16
- Product number
- NUT0000023
- Product name
- 3',4',5,7-TETRAHYDROXY-3-METHOXY FLAVONE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $2194.5
- Updated
- 2021/12/16
3-O-Methylquercetin Chemical Properties,Usage,Production
Description
3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.
Uses
A metabolite of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells.
Definition
ChEBI: A tetrahydroxyflavone having the 4-hydroxy groups located at the 3'- 4'- 5- and 7-positions as well as a methoxy group at the 2-position.
Biological Activity
3-O-Methylquercetin isolated from the herbs of Croton cascarilloides. It is a selective and competitive PDE3/PDE4 inhibitor,and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
Biochem/physiol Actions
3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
target
cAMP | PDE | IL Receptor | TNF-α | NOS | NO | Antifection
3-O-Methylquercetin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-O-Methylquercetin manufacturers
- Product
- 3-O-Methylquercetin 1486-70-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-03