3-O-Methylquercetin

Product Name: 3-O-Methylquercetin
CAS No.: 1486-70-0
Chemical Name: 3-O-Methylquercetin
Synonyms: NSC 154016;3-Methylquercetol;3-Methoxyluteolin;Rutoside Trihydrate Impurity 8;3',4',5,7-Tetrahydroxy-3-methoxyflavone;TETRAHYDROXY-3-METHOXYFLAVONE, 3',4',5,7-(RG);2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-chroMen-4-one;2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-1-benzopyran-4-one;2-(3,4-Dihydroxyphenyl)-3-methoxy-5,7-dihydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-
CBNumber: CB81075557
Molecular Formula: C16H12O7
Formula Weight: 316.26
MOL File: 1486-70-0.mol

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3-O-Methylquercetin Property

Melting point:: 275 °C
Boiling point:: 643.0±55.0 °C(Predicted)
Density: 1.69±0.1 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
pka: 6.31±0.40(Predicted)
color: Yellow
BRN: 324509
Stability:: Hygroscopic
LogP: 2.020 (est)

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 90081
Product name: 3-O-Methylquercetin
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $175.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 90081
Product name: 3-O-Methylquercetin
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $713
Updated: 2024/03/01

TRC

Product number: M326545
Product name: 3-O-MethylQuercetin
Packaging: 25mg
Price: $950
Updated: 2021/12/16

Matrix Scientific

Product number: 090947
Product name: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one
Purity: 95+%
Packaging: 250mg
Price: $1853
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUT0000023
Product name: 3',4',5,7-TETRAHYDROXY-3-METHOXY FLAVONE
Purity: 95.00%
Packaging: 50MG
Price: $2194.5
Updated: 2021/12/16

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3-O-Methylquercetin Chemical Properties,Usage,Production

Description

3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.

Uses

A metabolite of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells.

Definition

ChEBI: A tetrahydroxyflavone having the 4-hydroxy groups located at the 3'- 4'- 5- and 7-positions as well as a methoxy group at the 2-position.

Biological Activity

3-O-Methylquercetin isolated from the herbs of Croton cascarilloides. It is a selective and competitive PDE3/PDE4 inhibitor,and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.

Biochem/physiol Actions

3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.

target

cAMP | PDE | IL Receptor | TNF-α | NOS | NO | Antifection

3-O-Methylquercetin Preparation Products And Raw materials

Raw materials

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3-O-Methylquercetin Suppliers

Canada 1 China 93 Germany 1 India 1 South Korea 1 United Kingdom 3 United States 12 Global 112

Carbosynth

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Email: sales@carbosynth.com
Country: United Kingdom
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Apin Chemicals Limited (UK)

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Country: United Kingdom
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Sequoia Research Products Ltd.

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View Lastest Price from 3-O-Methylquercetin manufacturers

Career Henan Chemical Co

Product: 3-O-Methylquercetin 1486-70-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

1486-70-0, 3-O-MethylquercetinRelated Search:

ISORHAMNETIN-3-GLUCOSIDE Peltatoside Quercitrin Hyperoside QUERCETIN-3,7,3',4'-TETRAMETHYL ETHER Rutin 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE CASTICIN Myricitrin ISORHAMNETIN-3-RUTINOSIDE 3,3',5,7 TETRAHYDROXY-4'-METHOXYFLAVONE 3,4',5,7-Tetrahydroxy-6-methoxyflavone ISOQUERCITRIN QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE AVICULARIN 5-O-Methyl Quercetin;2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-Methoxy-4H-1-benzopyran-4-one 3,5,7,4'-TETRAHYDROXY-3'-METHOXYFLAVONE Rhamnetin

3',4',5,7-Tetrahydroxy-3-methoxyflavone

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-1-benzopyran-4-one

3-Methylquercetol

NSC 154016

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-4H-chroMen-4-one

2-(3,4-Dihydroxyphenyl)-3-methoxy-5,7-dihydroxy-4H-1-benzopyran-4-one

TETRAHYDROXY-3-METHOXYFLAVONE, 3',4',5,7-(RG)

4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-Methoxy-

Rutoside Trihydrate Impurity 8

3-Methoxyluteolin

3OMethylquercetin,Phosphodiesterase (PDE),inhibit,3 O Methylquercetin,Inhibitor

1486-70-0

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