Sulopenem
- Product Name
- Sulopenem
- CAS No.
- 120788-07-0
- Chemical Name
- Sulopenem
- Synonyms
- CP-70429;Sulopenem;CP-65207-S;Sulopenem USP/EP/BP;(S)-3-[[(5R)-2-Carboxy-6β-[(R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]tetrahydrothiophene 1-oxide;(5R,6S)-6-((R)-1-hydroxyethyl)-3-(((1R)-1-oxidotetrahydrothiophen-3-yl)thio)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-, (5R,6S)-
- CBNumber
- CB81116702
- Molecular Formula
- C12H15NO5S3
- Formula Weight
- 349.45
- MOL File
- 120788-07-0.mol
Sulopenem Property
- Boiling point:
- 693.1±55.0 °C(Predicted)
- Density
- 1.74±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 3.88±0.40(Predicted)
- form
- Solid
- color
- White to yellow
N-Bromosuccinimide Price
- Product number
- S789485
- Product name
- Sulopenem
- Packaging
- 0.5mg
- Price
- $415
- Updated
- 2021/12/16
- Product number
- API0006068
- Product name
- SULOPENEM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.13
- Updated
- 2021/12/16
- Product number
- CS-0025618
- Product name
- Sulopenem
- Purity
- 98.06%
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- DC32221
- Product name
- CP-70429
- Packaging
- 250mg
- Price
- $1600
- Updated
- 2021/12/16
Sulopenem Chemical Properties,Usage,Production
Description
Sulopenem is a parenteral penem that demonstrates high activity against Gram-positive, Gram-negative, and anaerobic bacteria. Since it is stable in relation to renal dehydropeptidase I, it does not require concomitant administration of an inhibitor of this enzyme.
Uses
Antibacterial.
Uses
Sulopenem is a β-Lactamase inhibitor which is used in treatment of microbial infections. It is an important reagent for many drugs synthesized against bacterial infections.
Mechanism of action
Sulopenem is one of the penems and, as such, interacts with penicillin-binding proteins (PBPs). From in vitro studies, sulopenem has shown a high affinity for PBP1a, 1b, 2, and 3 in E. coli.
Pharmacokinetics
When 1 g of CP-65,207 [containing 46.3% of S-isomer (sulopenem) and 53.7% of R-isomer] was administered by 10-minute intravenous infusions, the peak concentration of sulopenem in serum was 36.0 mg/ ml, its half-life was 52.8 minutes, and the area under the serum concentration-versus-time curve (AUC) from 0 to 8 hours was 21.0 mg/ml per hour.
Sulopenem Preparation Products And Raw materials
Raw materials
Preparation Products
Sulopenem Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77
- Tel
- --
- Fax
- --
- enquiry@leancare.co.uk
- Country
- United Kingdom
- ProdList
- 6446
- Advantage
- 42
View Lastest Price from Sulopenem manufacturers
- Product
- Sulopenem 120788-07-0
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1kg; 5kg; 10kg
- Release date
- 2020-10-28