ChemicalBook > CAS DataBase List > Sinitrodil
Sinitrodil
- Product Name
- Sinitrodil
- CAS No.
- 143248-63-9
- Chemical Name
- Sinitrodil
- Synonyms
- ITF296;ITF-296;ITF 296;Sinitrodil;Sinitrodil, 10 mM in DMSO
- CBNumber
- CB81117729
- Molecular Formula
- C10H10N2O5
- Formula Weight
- 238.198
- MOL File
- 143248-63-9.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0025263
- Product name
- SINITRODIL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.03
- Updated
- 2021/12/16
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Sinitrodil Chemical Properties,Usage,Production
Uses
Sinitrodil (ITF 296) is an orally active organic nitrate with anti-ischaemic effect. Sinitrodil can be used for acute and chronic heart diseases research[1][2].
in vivo
1.19
Pharmacokinetic parameters of Sinitrodil in rats[2]
Pharmacokinetic parameters of Sinitrodil in rats[2]
| Route | Parameter | Value |
| IV (1 mg/kg) | CL (L/h/kg) | 2.7 |
| AUC (μg h/mL) | 0.37 | |
| T1/2 (h) | 3.85 | |
| PO (5 mg/kg) | Tmax (h) | 0.17 |
| T1/2 (h) | 1.95 | |
| Cmax (μg/mL) | 2.099 | |
| CL (L/h/kg) | 2.69 | |
| AUC (μg h/mL) | 1.364 |
References
[1] Monzani MV, et al. Pharmacokinetics of ITF 296 (Sinitrodil) a novel organic nitrate, in healthy volunteers. Eur J Pharm Sci. 1999 Feb;7(3):179-84. DOI:10.1016/s0928-0987(98)00026-8
[2] Monzani MV, et al. Pharmacokinetic Profile of ITF 296 in Rats and Dogs. Journal of Cardiovascular Pharmacology 26:p S67-71,
Sinitrodil Preparation Products And Raw materials
Raw materials
Preparation Products
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Sinitrodil Suppliers
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