3-Nitrophthalic anhydride

Product Name: 3-Nitrophthalic anhydride
CAS No.: 641-70-3
Chemical Name: 3-Nitrophthalic anhydride
Synonyms: 1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomadomide impurity 36.;Pomalidomide Impurity 36
CBNumber: CB8116378
Molecular Formula: C8H3NO5
Formula Weight: 193.11
MOL File: 641-70-3.mol

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3-Nitrophthalic anhydride Property

Melting point:: 163-165 °C (lit.)
Boiling point:: 329.3°C (rough estimate)
Density: 1.6392 (rough estimate)
refractive index: 1.4700 (estimate)
storage temp.: Store below +30°C.
form: Crystalline Powder
color: Beige to yellow
Water Solubility: MAY DECOMPOSE
Sensitive: Moisture Sensitive
BRN: 179963
CAS DataBase Reference: 641-70-3(CAS DataBase Reference)
NIST Chemistry Reference: 3-Nitrophthalic anhydride(641-70-3)
EPA Substance Registry System: 1,3-Isobenzofurandione, 4-nitro- (641-70-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
F: 10-21
TSCA: Yes
HS Code: 29173980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.20903
Product name: 3-Nitrophthalic anhydride
Purity: for synthesis
Packaging: 25g
Price: $87.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.20903
Product name: 3-Nitrophthalic anhydride
Purity: for synthesis
Packaging: 100g
Price: $164
Updated: 2024/03/01

Sigma-Aldrich

Product number: 156884
Product name: 3-Nitrophthalic anhydride
Purity: 98%
Packaging: 5g
Price: $76.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 156884
Product name: 3-Nitrophthalic anhydride
Purity: 98%
Packaging: 25g
Price: $148.8
Updated: 2024/03/01

TCI Chemical

Product number: N0245
Product name: 3-Nitrophthalic Anhydride
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $33
Updated: 2024/03/01

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3-Nitrophthalic anhydride Chemical Properties,Usage,Production

Chemical Properties

Beige to yellow crystalline powder

Uses

An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.

Uses

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.

Preparation

3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.

Purification Methods

Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]

3-Nitrophthalic anhydride Preparation Products And Raw materials

Raw materials

3-Nitrophthalic acid

Preparation Products

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3-Nitrophthalic anhydride Suppliers

Americas 1 Belgium 2 Canada 2 CHINA 315 Europe 1 France 1 Germany 7 India 23 Japan 4 Poland 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 17 United States 46 Global 424

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View Lastest Price from 3-Nitrophthalic anhydride manufacturers

Asia Chem I and E (Jiangsu) Co Ltd

Product: 3-Nitrophthalic anhydride 641-70-3
Price: US $62.79/Kg/Drum
Min. Order: 25Kg/Drum
Purity: 98.00%HPLC
Supply Ability: 8.8tons/month
Release date: 2021-09-23

Hebei Chuanghai Biotechnology Co,.LTD

Product: 3-Nitrophthalic anhydride 641-70-3
Price: US $10.70/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-23

Hebei Kangcang new material Technology Co., LTD

Product: 3-Nitrophthalic anhydride 641-70-3
Price: US $9.00-80.00/g
Min. Order: 10g
Purity: min99%
Supply Ability: 10 tons
Release date: 2024-03-26

641-70-3, 3-Nitrophthalic anhydrideRelated Search:

3-Fluorophthalic anhydride 4-BROMO PHTHALIC ANHYDRUS Dimethyl phthalate cis-1,2,3,6-Tetrahydrophthalic anhydride Isatoic Anhydride 2-Nitrobenzoic acid 2-Nitrobenzaldehyde CIS-BUTENEDIOIC ANHYDRIDE PHTHALAMIDE O-Phthalimide Dibutyl phthalate Phthalonitrile Phthalic anhydride 3-Nitrophthalic acid 3-Nitrophthalhydrazide 3-Nitrophthalimide METHYL 2-NITROBENZOATE 3-(METHOXYMETHYL)ANILINE

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3-Nitrophthalic anhydride, synthesis grade

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4-NITRO-ISOBENZOFURAN-1,3-DIONE

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NSC 27006

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1-Amino-2-Indolinon (CIS)

4-Nitro-1,3-iso benzofurandione

3-NITROPHTHALIC ANHYDRIDE ,99+%

3-NitrophthaL

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3-NitrophthalicAnhydride&gt

3-NITROPHTHALIC ANHYDRIDE FOR SYNTHESIS

Pomalidomide INT

Pomalidomide Impurity 36

RSSYY(Perospirone Hydrochloride Hydrate)-9

3-Nitrophthalic anhydride?New

Apremilast Impurity 90

Pomadomide impurity 36.

641-70-3

C8H3NO5

O2NC6H3CO2O

Organic Building Blocks

Carbonyl Compounds

Carboxylic Acid Anhydrides

Building Blocks

Anhydride Monomers

Monomers

Polymer Science

Carbonyl Compounds

Carboxylic Acid Anhydrides

Organic Building Blocks

Building Blocks

Carbonyl Compounds

Carboxylic Acid Anhydrides

Chemical Synthesis

Organic Building Blocks

Amines

Aromatics

Intermediates

Phthalic Acids, Esters and Derivatives

Dyes intermediates