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Ethyl propiolate

Product Name
Ethyl propiolate
CAS No.
623-47-2
Chemical Name
Ethyl propiolate
Synonyms
Ethyl prop-2-ynoate;EPL;Ethyl propargylate;Ethyl propynoate;Ethyl 2-propynoate;PropioL;HC≡CCO2C2H5;Ethyl propinate;ETHYL PROPIOLATE;EthylPropiolate>
CBNumber
CB8116565
Molecular Formula
C5H6O2
Formula Weight
98.1
MOL File
623-47-2.mol
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Ethyl propiolate Property

Melting point:
9°C
Boiling point:
120 °C (lit.)
Density 
0.968 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.412(lit.)
Flash point:
74 °F
storage temp. 
2-8°C
solubility 
Miscible with alcohol.
form 
Liquid
Specific Gravity
0.968
color 
Clear colorless to pale yellow
Water Solubility 
miscible
Merck 
14,3846
BRN 
878250
Dielectric constant
7.0
CAS DataBase Reference
623-47-2(CAS DataBase Reference)
NIST Chemistry Reference
Ethyl propiolate(623-47-2)
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Safety

Hazard Codes 
Xi,F
Risk Statements 
10-36/37/38-36-11
Safety Statements 
26-36-37/39-16-33-29-24-23
RIDADR 
UN 3272 3/PG 3
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
3
PackingGroup 
II
HS Code 
29161980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E46607
Product name
Ethyl propiolate
Purity
99%
Packaging
5g
Price
$56
Updated
2024/03/01
Sigma-Aldrich
Product number
E46607
Product name
Ethyl propiolate
Purity
99%
Packaging
25g
Price
$143
Updated
2024/03/01
TCI Chemical
Product number
P0529
Product name
Ethyl Propiolate
Purity
>98.0%(GC)
Packaging
5mL
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
P0529
Product name
Ethyl Propiolate
Purity
>98.0%(GC)
Packaging
25mL
Price
$143
Updated
2024/03/01
Alfa Aesar
Product number
A15068
Product name
Ethyl propiolate, 99%
Packaging
5g
Price
$44.65
Updated
2024/03/01
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Ethyl propiolate Chemical Properties,Usage,Production

Chemical Properties

Ethyl propiolate is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.

Uses

Halogenated derivatives were used as substrates for direct, asymmetric alkynylation of cyclic ?-ketoesters using chiral phase-transfer catalysts. Also employed in a one-pot , four-component synthesis of benzene-1,2,3,5-tetracarboxylates promoted by Ph3P.

Uses

Ethyl propiolate is used as a precursor in the preparation of substituted anthraquinones and pyrazolo[1,5-a]pyridine, which exhibits anti-inflammatory activity. Further, it is employed in the synthesis of benzene-1,2,3,5-tetracarboxylates promoted by triphenylphosphine. Its halogenated derivatives are used as a substrate for direct, asymmetric alkynylation of cyclic beta-ketoesters using chiral phase-transfer catalysts.

Uses

In organic synthesis; peptide coupling reagent.

Definition

ChEBI: Ethyl propiolate is the ethyl ester of prop-2-ynoic acid. It is a ynoate ester, a terminal acetylenic compound and an ethyl ester.

Hazard

Flammable; lachrymator.

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Ethyl propiolate Suppliers

CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
--
Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
Merck Millipore
Tel
--
Fax
--
Email
ccc@merckgroup.com
Country
Germany
ProdList
2008
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from Ethyl propiolate manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Ethyl propiolate 623-47-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
5MT/Month
Release date
2024-04-08
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl propiolate 623-47-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
Ethyl propiolate 623-47-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

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