ChemicalBook > CAS DataBase List > Lavoltidine

Lavoltidine

Product Name
Lavoltidine
CAS No.
76956-02-0
Chemical Name
Lavoltidine
Synonyms
Loxtidina;loxtidine;AH-234844;Lavoltidine;Lavoltidina;Lavoltidinum;Lavoltidine [inn:ban];Lavoltidinum [inn-latin];Lavoltidina [inn-spanish];86160-82-9 (Hemisuccinate[1:1])
CBNumber
CB81179004
Molecular Formula
C19H29N5O2
Formula Weight
359.471
MOL File
76956-02-0.mol
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0011760
Product name
LAVOLTIDINE
Purity
95.00%
Packaging
5MG
Price
$501.51
Updated
2021/12/16
More
Less

Lavoltidine Chemical Properties,Usage,Production

Uses

Anti-ulcerative (histamine H2-receptor block er).

Definition

ChEBI: Loxtidine is a triazole that consists of 1,2,4-triazole bearing a methyl substituent at position 1, a hydroxymethyl substituent at position 3 and a {3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino group at position 5. A highly potent and selective H2-receptor antagonist. It has a role as a H2-receptor antagonist. It is a member of triazoles, a member of piperidines, an aromatic ether and a primary alcohol.

in vivo

Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1].
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].

Animal Model:Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1]
Dosage:0.5 g/L
Administration:Orally (drinking water); changed weekly; for 3 months
Result:Showed partial suppression of both gastric acid secretion and progression to neoplasia.

IC 50

H2 Receptor

Lavoltidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Lavoltidine Suppliers

China 6 United States 3 Global 9
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

76956-02-0, LavoltidineRelated Search:

1,3-DIMETHYL-1H-1,2,4-TRIAZOL-5-AMINE CHEMBRDG-BB 9071718 N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]amine 3-(1-Piperidinylmethyl)phenol Lavoltidine

  • 1-Methyl-5-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]amino]-1H-1,2,4-triazole-3-methanol
  • 1H-1,2,4-Triazole-3-methanol, 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)-
  • 86160-82-9 (Hemisuccinate[1:1])
  • Lavoltidina
  • Lavoltidina [inn-spanish]
  • Lavoltidine [inn:ban]
  • Lavoltidinum
  • Lavoltidinum [inn-latin]
  • Loxtidina
  • Lavoltidine
  • loxtidine
  • AH-234844
  • 76956-02-0