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Lexacalcitol

Product Name
Lexacalcitol
CAS No.
131875-08-6
Chemical Name
Lexacalcitol
Synonyms
KH 106;KH 1060;Lexacalcitol;Lenosacalcitol;Lexacalcideferol;(1S*,3R*,5Z),7aalpha))-(5Z,7E,20R)-20-((4-Ethyl-4-hydroxyhexyl)oxy)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol;1,3-Cyclohexanediol, 5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-;(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-(4-ethyl-4-hydroxyhexoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
CBNumber
CB81179039
Molecular Formula
C29H48O4
Formula Weight
460.69
MOL File
131875-08-6.mol
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Lexacalcitol Property

Boiling point:
600.3±55.0 °C(Predicted)
Density 
1.07±0.1 g/cm3(Predicted)
storage temp. 
-20°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
solubility 
DMSO
form 
Powder
pka
14.43±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
L397700
Product name
Lexacalcitol
Packaging
0.1mg
Price
$370
Updated
2021/12/16
TRC
Product number
L397700
Product name
Lexacalcitol
Packaging
1mg
Price
$3125
Updated
2021/12/16
ChemScene
Product number
CS-0399
Product name
Lexacalcitol
Purity
99.42%
Packaging
1mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
VIT0000071
Product name
LEXACALCITOL
Purity
95.00%
Packaging
5MG
Price
$495.8
Updated
2021/12/16
ChemScene
Product number
CS-0399
Product name
Lexacalcitol
Purity
99.42%
Packaging
5mg
Price
$800
Updated
2021/12/16
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Lexacalcitol Chemical Properties,Usage,Production

Uses

Lexacalcitol is a 20-epi vitamin D3 analog with potent antitumor, calcemic, and immunosuppressive activity.

in vivo

Lexacalcitol (0.5 mg/kg/2 days; i.p.) in combination with cyclosporin A (CyA) can prevent autoimmune destruction of syngeneic islet grafts in spontaneously diabetic NOD recipients[2].

Animal Model:Male and female spontaneously diabetic NOD mice[2]
Dosage:0.5 mg/kg/2 days
Administration:Intraperitoneal injection
Result:Single treatment with KH1060 or CyA did not result in statistically significant suppression of early graft failure, while the combination of KH1060 and CyA can prevent early graft failure and delay graft rejection of xenogeneic islets in spontaneously diabetic NOD mice.

Lexacalcitol Preparation Products And Raw materials

Raw materials

Preparation Products

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Lexacalcitol Suppliers

Wuhan Wsem Biological Co., Ltd.
Tel
027-83778876 13667159345
Fax
027-83778876
Email
13667159345@163.com
Country
China
ProdList
1997
Advantage
55
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Hydragon Pharma Ltd
Tel
021-50215258
Fax
021-50215756
Email
market@hypharma.com
Country
China
ProdList
321
Advantage
58
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Gansu HaoTian Chemical Technology Co., Ltd.
Tel
0943-6900332 17789447501
Fax
0931-8238232
Email
zhuanxiajiang@haotianpharm.com
Country
China
ProdList
192
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
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View Lastest Price from Lexacalcitol manufacturers

Career Henan Chemical Co
Product
Lexacalcitol 131875-08-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13
Career Henan Chemical Co
Product
Lexacalcitol 131875-08-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

131875-08-6, LexacalcitolRelated Search:


  • Lexacalcitol
  • (1S*,3R*,5Z),7aalpha))-(5Z,7E,20R)-20-((4-Ethyl-4-hydroxyhexyl)oxy)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol
  • KH 106
  • (1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-(4-ethyl-4-hydroxyhexoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
  • KH 1060
  • Lenosacalcitol
  • 1,3-Cyclohexanediol, 5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-
  • Lexacalcideferol
  • 131875-08-6