ChemicalBook > CAS DataBase List > Lexacalcitol
Lexacalcitol
- Product Name
- Lexacalcitol
- CAS No.
- 131875-08-6
- Chemical Name
- Lexacalcitol
- Synonyms
- KH 106;KH 1060;Lexacalcitol;Lenosacalcitol;Lexacalcideferol;(1S*,3R*,5Z),7aalpha))-(5Z,7E,20R)-20-((4-Ethyl-4-hydroxyhexyl)oxy)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol;1,3-Cyclohexanediol, 5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-;(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-(4-ethyl-4-hydroxyhexoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
- CBNumber
- CB81179039
- Molecular Formula
- C29H48O4
- Formula Weight
- 460.69
- MOL File
- 131875-08-6.mol
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Lexacalcitol Property
- Boiling point:
- 600.3±55.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
- solubility
- DMSO
- form
- Powder
- pka
- 14.43±0.40(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
TRC
- Product number
- L397700
- Product name
- Lexacalcitol
- Packaging
- 0.1mg
- Price
- $370
- Updated
- 2021/12/16
TRC
- Product number
- L397700
- Product name
- Lexacalcitol
- Packaging
- 1mg
- Price
- $3125
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0399
- Product name
- Lexacalcitol
- Purity
- 99.42%
- Packaging
- 1mg
- Price
- $350
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- VIT0000071
- Product name
- LEXACALCITOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.8
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0399
- Product name
- Lexacalcitol
- Purity
- 99.42%
- Packaging
- 5mg
- Price
- $800
- Updated
- 2021/12/16
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Lexacalcitol Chemical Properties,Usage,Production
Uses
Lexacalcitol is a 20-epi vitamin D3 analog with potent antitumor, calcemic, and immunosuppressive activity.
in vivo
Lexacalcitol (0.5 mg/kg/2 days; i.p.) in combination with cyclosporin A (CyA) can prevent autoimmune destruction of syngeneic islet grafts in spontaneously diabetic NOD recipients[2].
| Animal Model: | Male and female spontaneously diabetic NOD mice[2] |
| Dosage: | 0.5 mg/kg/2 days |
| Administration: | Intraperitoneal injection |
| Result: | Single treatment with KH1060 or CyA did not result in statistically significant suppression of early graft failure, while the combination of KH1060 and CyA can prevent early graft failure and delay graft rejection of xenogeneic islets in spontaneously diabetic NOD mice. |
Lexacalcitol Preparation Products And Raw materials
Raw materials
Preparation Products
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Lexacalcitol Suppliers
- Tel
- 027-83778876 13667159345
- Fax
- 027-83778876
- 13667159345@163.com
- Country
- China
- ProdList
- 1997
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- +86-21-20908456
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- 021-58180499
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- China
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- 001-857-928-2050 or 1-888-588-9418
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- 001-617-206-9595
- sales@chemreagents.com
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- United States
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- 021-50215258
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- 021-50215756
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- +86-21-5821 5861
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- +86-21-5106 2861
- sales@letopharm.com
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- China
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- 0943-6900332 17789447501
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- 0931-8238232
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- China
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- +86-20-62619665
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- 400-1166-196 15982826727
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- QQ:800101999
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- Tel
- +1-800-259-7612
- Fax
- +1-800-259-7612
- info@musechem.com
- Country
- United States
- ProdList
- 4660
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View Lastest Price from Lexacalcitol manufacturers
Career Henan Chemical Co
- Product
- Lexacalcitol 131875-08-6
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-13
Career Henan Chemical Co
- Product
- Lexacalcitol 131875-08-6
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-13