ChemicalBook > CAS DataBase List > Lexacalcitol

Lexacalcitol

Product Name: Lexacalcitol
CAS No.: 131875-08-6
Chemical Name: Lexacalcitol
Synonyms: KH 106;KH 1060;Lexacalcitol;Lenosacalcitol;Lexacalcideferol;(1S*,3R*,5Z),7aalpha))-(5Z,7E,20R)-20-((4-Ethyl-4-hydroxyhexyl)oxy)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol;1,3-Cyclohexanediol, 5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-;(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-(4-ethyl-4-hydroxyhexoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
CBNumber: CB81179039
Molecular Formula: C29H48O4
Formula Weight: 460.69
MOL File: 131875-08-6.mol

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Lexacalcitol Property

Boiling point:: 600.3±55.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: -20°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
solubility: DMSO
form: Powder
pka: 14.43±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: L397700
Product name: Lexacalcitol
Packaging: 0.1mg
Price: $370
Updated: 2021/12/16

TRC

Product number: L397700
Product name: Lexacalcitol
Packaging: 1mg
Price: $3125
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb134742
Product name: Lexacalcitol
Purity: >99%
Packaging: 250mg
Price: $4469.3
Updated: 2021/12/16

ChemScene

Product number: CS-0399
Product name: Lexacalcitol
Purity: 99.42%
Packaging: 1mg
Price: $350
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb134742
Product name: Lexacalcitol
Purity: >99%
Packaging: 1g
Price: $8916.5
Updated: 2021/12/16

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Lexacalcitol Chemical Properties,Usage,Production

Uses

Lexacalcitol is a 20-epi vitamin D3 analog with potent antitumor, calcemic, and immunosuppressive activity.

in vivo

Lexacalcitol (0.5 mg/kg/2 days; i.p.) in combination with cyclosporin A (CyA) can prevent autoimmune destruction of syngeneic islet grafts in spontaneously diabetic NOD recipients^[2].

Animal Model:	Male and female spontaneously diabetic NOD mice^[2]
Dosage:	0.5 mg/kg/2 days
Administration:	Intraperitoneal injection
Result:	Single treatment with KH1060 or CyA did not result in statistically significant suppression of early graft failure, while the combination of KH1060 and CyA can prevent early graft failure and delay graft rejection of xenogeneic islets in spontaneously diabetic NOD mice.

Lexacalcitol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Lexacalcitol manufacturers

Career Henan Chemical Co

Product: Lexacalcitol 131875-08-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

Career Henan Chemical Co

Product: Lexacalcitol 131875-08-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

131875-08-6, LexacalcitolRelated Search:

Paricalcitol 1,2-DIMETHYLENE-CYCLOHEXANE Lexacalcitol

Lexacalcitol

(1S*,3R*,5Z),7aalpha))-(5Z,7E,20R)-20-((4-Ethyl-4-hydroxyhexyl)oxy)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol

KH 106

(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-(4-ethyl-4-hydroxyhexoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

KH 1060

Lenosacalcitol

1,3-Cyclohexanediol, 5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-

Lexacalcideferol

131875-08-6