Mazaticol
- Product Name
- Mazaticol
- CAS No.
- 42024-98-6
- Chemical Name
- Mazaticol
- Synonyms
- 2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, exo-;α-Hydroxy-α-(2-thienyl)-2-thiopheneacetic acid (1α,5α)-6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3α-yl ester;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, rel-;2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, (1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, rel- (9CI)
- CBNumber
- CB81179099
- Molecular Formula
- C21H27NO3S2
- Formula Weight
- 405.57
- MOL File
- 42024-98-6.mol
Mazaticol Property
- Boiling point:
- 528.7±50.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- pka
- 10.34±0.29(Predicted)
N-Bromosuccinimide Price
- Product number
- API0011843
- Product name
- MAZATICOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.49
- Updated
- 2021/12/16
Mazaticol Chemical Properties,Usage,Production
Originator
Pentona, Tanabe ,Japan ,1978
Definition
ChEBI: Mazaticol is a member of piperidines.
Manufacturing Process
A mixture of 1.0 g of 6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol, methyl α,α-di-(2-thienyl)-glycolate and 30 mg of metallic sodium is heated at 80°C to 90°C for about 2 hours under reduced pressure. After cooling, ether is added to the reaction mixture. The mixture is extracted with 10% hydrochloric acid. The aqueous layer is alkalified with sodium carbonate and reextracted with ethyl acetate. The extract is washed with water, dried and concentrated to dryness. The residue thus obtained is treated with hydrogen chloride by conventional manner. 2.0 g of the α,α-di-(2-thienyl)glycolate of 6,6,9- trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol hydrochloride are obtained. Yield 83%.
Therapeutic Function
Antiparkinsonian
Mazaticol Preparation Products And Raw materials
Raw materials
Preparation Products
Mazaticol Suppliers
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24131
- Advantage
- 58