2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE

Product Name: 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE
CAS No.: 936-16-3
Chemical Name: 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE
Synonyms: 1,2-benzoisothiazoline 1,1-dioxide;2,3-dihydro-1,2-benzothiazole 1,1-dioxide;2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE;2,3-Dihydrobenzo[d]isothiazole 1,1-dioxide;2,3-dihydro-1,2-benzisothiazole 1,1-dioxide;1,2-Benzisothiazole, 2,3-dihydro-, 1,1-dioxide;2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
CBNumber: CB8123446
Molecular Formula: C7H7NO2S
Formula Weight: 169.2
MOL File: 936-16-3.mol

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2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Property

Melting point:: 105-107 °C(Solv: water (7732-18-5))
Boiling point:: 325.8±45.0 °C(Predicted)
Density: 1.396±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.21±0.20(Predicted)
Appearance: White to off-white Solid

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: B204043
Product name: 2,3-Dihydro-1,2-benzisothiazole1,1-Dioxide
Packaging: 50mg
Price: $130
Updated: 2021/12/16

AK Scientific

Product number: 0680BA
Product name: 2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
Packaging: 1g
Price: $521
Updated: 2021/12/16

Apolloscientific

Product number: OR912878
Product name: 2,3-Dihydro-1,1-dioxo-1,2-benzisothiazole
Purity: 95%
Packaging: 1g
Price: $545
Updated: 2021/12/16

AK Scientific

Product number: 0680BA
Product name: 2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
Packaging: 100mg
Price: $176
Updated: 2021/12/16

AK Scientific

Product number: 0680BA
Product name: 2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
Packaging: 250mg
Price: $208
Updated: 2021/12/16

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2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Chemical Properties,Usage,Production

Synthesis

81-07-2

936-16-3

Step 1. Saccharin (10.0 g, 54.6 mmol) was slowly added to a 300 mL THF solution of LiAlH4 (2.24 g, 59.0 mmol) at 0 °C. The reaction mixture was stirred at 15 °C for 3 h in an inert atmosphere. Upon completion of the reaction, EtOAc (100 mL) was slowly added followed by 10% H2SO4 (100 mL). The organic layer was separated and washed with 100 mL of 5% sodium carbonate solution, dried over anhydrous sodium sulfate, filtered and concentrated to afford 1,2-dihydro-1,1-dioxo-1,2-benzisothiazole (4.4 g, 97%).

References

[1] Patent: WO2018/49324, 2018, A1. Location in patent: Page/Page column 25
[2] Organic Letters, 2014, vol. 16, # 6, p. 1550 - 1553
[3] Patent: WO2017/21805, 2017, A1. Location in patent: Page/Page column 174
[4] Patent: US2013/303524, 2013, A1. Location in patent: Paragraph 0268-0269
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 19, p. 8868 - 8878

2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Suppliers

China 47 France 1 India 1 United Kingdom 1 United States 3 Global 53

Shanghai Sheepchem Co., Ltd.

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Yancheng Schiemann Biological Technology Co.,Ltd

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Chengdu Apis Pharmaceutical Technology Co.,Ltd

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Shanghai Haohong Pharmaceutical Co., Ltd.

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View Lastest Price from 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE manufacturers

Career Henan Chemical Co

Product: 2,3-dihydro-1,2-benzothiazole 1,1-dioxide 936-16-3
Price: US $1.00/KG
Min. Order: 1g
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-21

936-16-3, 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLERelated Search:

6-Nitro-1,2-benzisothiazolin-3-one 1,1-dioxide Saccharin N-METHYLSACCHARIN methyl 3-oxo1,2-benzisothiazole-2(3H)-acetate 1,1-dioxide 1,1-DIOXO-2-(2-OXO-PROPYL)-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE 1,2-BENZISOTHIAZOL-3(2H)-ONE, 5-BROMO, 1,1-DIOXIDE N-(2-NITROPHENYLTHIO)SACCHARIN, 95% denatonium saccharide (1,1,3-TRIOXO-1,3-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-2-YL)-ACETONITRILE N-CHLOROSACCHARIN N-HYDROXYMETHYLSACCHARIN 2,3-DIHYDRO-3,3-DIMETHYL-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE CALCIUM SACCHARIN HYDRATE 2,3-DIHYDRO-3,3-DIMETHYL-2-FLUORO-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE AKOS 228-11 RARECHEM AM UH 007B AKOS BBS-00002600 AKOS 228-40

2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione

2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE

1,2-benzoisothiazoline 1,1-dioxide

2,3-dihydro-1,2-benzothiazole 1,1-dioxide

2,3-dihydro-1,2-benzisothiazole 1,1-dioxide

2,3-Dihydrobenzo[d]isothiazole 1,1-dioxide

1,2-Benzisothiazole, 2,3-dihydro-, 1,1-dioxide

936-16-3

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