(R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL

Product Name: (R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL
CAS No.: 77119-85-8
Chemical Name: (R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL
Synonyms: Boc-D-Phe-aldehyde;BOC-D-PHENYLALANINAL;N-BOC-D-PHENYLALANINAL;N-T-BOC-D-PHENYLALANINAL;N-Boc-D-phenylalaninal 97%;N-BOC-D-Phenylalaninal,97%;N-Boc-2(R)-3-phenylpropanal;N-Boc-D-phenylalaninal;N-(tert-Butoxycarbonyl)-D-phenylalaninal;(R)-(+)-2-(tert-butoxycarbonylamino)-3-phenylprop
CBNumber: CB8126917
Molecular Formula: C14H19NO3
Formula Weight: 249.31
MOL File: 77119-85-8.mol

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(R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL Property

Melting point:: 86-89 °C (lit.)
storage temp.: -20°C
form: Crystalline Powder
color: White or tan
optical activity: [α]20/D +45°, c = 0.5 in methanol

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Safety

WGK Germany: 3
HS Code: 29223900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 469289
Product name: N-Boc-D-phenylalaninal
Purity: 97%
Packaging: 1g
Price: $172
Updated: 2022/05/15

Biosynth Carbosynth

Product number: FB50585
Product name: Boc-D-phenylalaninal
Packaging: 250mg
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4156-1-R0
Product name: N-Boc-D-Phenylalaninal
Purity: 95%
Packaging: 250mg
Price: $93
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50585
Product name: Boc-D-phenylalaninal
Packaging: 500mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50585
Product name: Boc-D-phenylalaninal
Packaging: 1g
Price: $200
Updated: 2021/12/16

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(R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL Chemical Properties,Usage,Production

Chemical Properties

White or tan crystalline powder

Uses

Boc-D-phenylalaninal is a useful research chemical compound used as a reactant in the copper(I)-catalyzed synthesis of 1,2,3-triazoles as inhibitors of human immunodeficiency virus type 1 protease.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

19901-50-9

77119-85-8

A toluene solution of DIBAL-H (1.0 M, 179 mL, 179 mmol) was added slowly and dropwise to a toluene-DCM (4:1, 1000 mL) solution of Compound 31c (25.0 g, 90 mmol) under stirring at -78 °C. The reaction was carried out under argon protection, followed by slow warming to room temperature and continuous stirring at this temperature for 1 hour. Immediately after completion of the reaction, methanol (200 mL) was added to quench the reaction. The reaction mixture was poured into 200 mL of 20% aqueous sodium potassium tartrate (Rochelle salt) and stirred at room temperature until the two phases were clearly separated. The organic layer was separated, concentrated under vacuum and the residue was purified by column chromatography (eluent: hexane/ethyl acetate = 2:1) to afford the target product compound 31d as a white solid (19.9 g, 89% yield).

References

[1] Patent: WO2011/107248, 2011, A1. Location in patent: Page/Page column 68; 69
[2] Journal of Medicinal Chemistry, 1993, vol. 36, # 2, p. 211 - 220
[3] Heterocycles, 1998, vol. 48, # 7, p. 1331 - 1335
[4] The Journal of organic chemistry, 2002, vol. 67, # 17, p. 6162 - 6173
[5] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 20, p. 2983 - 2996

(R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL Suppliers

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View Lastest Price from (R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL manufacturers

Career Henan Chemical Co

Product: (R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL 77119-85-8
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-10

77119-85-8, (R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANALRelated Search:

(S)-(-)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL N-BOC-L-Prolinal BOC-ARG-OH BOC-L-NORLEUCINE BOC-D-ABU-OH BOC-D-MEPHE-OH DCHA BOC-D-Phenylalanine Boc-3-(2-Naphthyl)-D-alanine BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER BOC-D-4-Fluorophe (S)-N-Boc-1-Naphthylalanine N-tert-Butyloxycarbonyl-O-(2-bromobenzyloxycarbonyl)-D-tyrosine BOC-D-4-Chlorophe BOC-D-TYR(ET)-OH BOC-D-4-Nitrophe BOC-D-TYR(BZL)-OH Boc-D-Tyr-OH BOC-D-4-IODOPHENYLALANINE

BOC-D-PHENYLALANINAL

N-T-BOC-D-PHENYLALANINAL

N-BOC-D-PHENYLALANINAL

(R)-(+)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANAL

(R)-(+)-2-(tert-butoxycarbonylamino)-3-phenylprop

N-BOC-D-Phenylalaninal,97%

N-Boc-D-phenylalaninal 97%

tert-butyl(R)-(1-oxo-3-phenylpropan-2-yl)carbamate

N-Boc-2(R)-3-phenylpropanal

tert-butyl N-[(2R)-1-oxo-3-phenylpropan-2- yl]carbaMate

tert-Butyl-[(2R)-1-oxo-3-phenylpropan-2-yl]carbaMat

N-[(2R)-1-oxo-3-phenylpropan-2-yl]carbamic acid tert-butyl ester

N-(tert-Butoxycarbonyl)-D-phenylalaninal

Carbamic acid, N-[(1R)-1-formyl-2-phenylethyl]-, 1,1-dimethylethyl ester

Boc-D-Phe-aldehyde

<i>N</i>-Boc-<sc>D</sc>-phenylalaninal

(R)-tert-Butyl (1-oxo-3-phenylpropan-2-yl)carbamate - [B91283]

77119-85-8

C6H5CH2CHNHCO2CCH33CHO

Amino Acid Derivatives

Amino Aldehydes

ALDEHYDE

Peptide Synthesis

Specialty Synthesis