2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
- Product Name
- 2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
- CAS No.
- 61856-99-3
- Chemical Name
- 2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
- Synonyms
- EMPO;2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE;2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-2-methyl-, ethyl ester, 1-oxide
- CBNumber
- CB8131546
- Molecular Formula
- C8H13NO3
- Formula Weight
- 171.19
- MOL File
- Mol file
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Property
- Boiling point:
- 120 °C(Press: 0.3 Torr)
- Density
- 1.249 g/cm3
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
- pka
- 1.79±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 20618
- Product name
- EMPO
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 20618
- Product name
- EMPO
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $84
- Updated
- 2024/03/01
- Product number
- 20618
- Product name
- EMPO
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 20618
- Product name
- EMPO
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $299
- Updated
- 2024/03/01
- Product number
- 3241CT
- Product name
- 2H-Pyrrole-2-carboxylicacid,3,4-dihydro-2-methyl-,ethylester,1-oxide
- Packaging
- 25mg
- Price
- $289
- Updated
- 2021/12/16
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Chemical Properties,Usage,Production
Description
EMPO is a hydrophilic cyclic nitrone analog of the free radical spin trap DMPO . The EMPO-superoxide adduct (EMPO-OOH) exhibits an ESR spectrum that is similar to the DMPO-OOH spectrum. However, the EMPO-OOH adduct is about 5-8 times more stable (t1/2 = 4.8 – 8.6 min) and does not spontaneously decay to the hydroxyl adduct, making spectral interpretation less difficult.
Uses
EMPO is a free radical scavenger. EMPO is stable in phosphate buffers at physiological pH, its superoxide spin adducts are more durable and no hydroxyl adducts are produced when decaying. EMPO can be used in the study of free radicals[1].
References
[1] Olive G, et al. 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide: evaluation of the spin trapping properties. Free Radic Biol Med. 2000 Feb 1;28(3):403-8. DOI:10.1016/s0891-5849(99)00254-3
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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