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alpha-Methyl-4-biphenylacetic acid

Product Name
alpha-Methyl-4-biphenylacetic acid
CAS No.
6341-72-6
Chemical Name
alpha-Methyl-4-biphenylacetic acid
Synonyms
LY-71130;p-Phenylhydratropic Acid;p-Phenylhydroatropic acid;Flurbiprofen EP impurity A;Flurbiprofen impurity A CRS;Flurbiprofen EP impurity A -E;Flurbiprofen axetil impurity5;α-Methylbiphenyl-4-acetic acid;α-Methyl-4-biphenylacetic acid;2-(4-Biphenylyl)propionic Acid
CBNumber
CB81401675
Molecular Formula
C15H14O2
Formula Weight
226.27
MOL File
6341-72-6.mol
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alpha-Methyl-4-biphenylacetic acid Property

Melting point:
168-169 °C
Boiling point:
388.3±21.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
form 
solid
pka
4.34±0.10(Predicted)
color 
White to off-white
Major Application
pharmaceutical small molecule
InChI
1S/C15H14O2/c1-11(15(16)17)12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-11H,1H3,(H,16,17)
InChIKey
JALUUBQFLPUJMY-UHFFFAOYSA-N
SMILES
OC(=O)C(C)c1ccc(cc1)c2ccccc2
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Safety

RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
HS Code 
2916399000
Storage Class
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 3 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2710
Product name
Flurbiprofen Related Compound A
Purity
PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial,certifiedrefer
Packaging
100MG
Price
$777
Updated
2026/03/19
Sigma-Aldrich
Product number
F0285202
Product name
Flurbiprofen impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
25 mg
Price
$175
Updated
2026/03/19
Sigma-Aldrich
Product number
BP046
Product name
2-(Biphenyl-4-yl)propionic acid
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
25MG
Price
$292
Updated
2026/03/19
Sigma-Aldrich
Product number
1285760
Product name
Flurbiprofen impurity A
Packaging
100mg
Price
$1460
Updated
2026/03/19
Sigma-Aldrich
Product number
F0285202
Product name
Flurbiprofen impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
f0285202
Price
$153
Updated
2024/03/01
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alpha-Methyl-4-biphenylacetic acid Chemical Properties,Usage,Production

Uses

A metabolite of Isopropylbiphenyl, a COX-2 selective inhibitor. Also an impurity of Flurbiprofen (F598700).

Synthesis Reference(s)

Synthesis, p. 456, 1982 DOI: 10.1055/s-1982-29832

alpha-Methyl-4-biphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha-Methyl-4-biphenylacetic acid Suppliers

Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5157
Advantage
50
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4769
Advantage
55
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
Advantage
60
Quality Control Solutions Ltd.
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
orders@qcsrm.com
Country
China
ProdList
18421
Advantage
56
Shandong Boluoda Biological Technology Co., Ltd.
Tel
0531-68659041
Email
2310993908@qq.com
Country
China
ProdList
2917
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 17714375163
Email
yftan@aikonchem.com
Country
China
ProdList
16676
Advantage
50
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
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View Lastest Price from alpha-Methyl-4-biphenylacetic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2-(4-phenylphenyl)propanoic acid 6341-72-6
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-05

6341-72-6, alpha-Methyl-4-biphenylacetic acidRelated Search:


  • alpha-Methyl-4-biphenylacetic acid
  • 2-(Biphenyl-4-yl)propanoic acid
  • LY-71130
  • p-Phenylhydroatropic acid
  • α-Methyl-4-biphenylacetic acid
  • α-Methylbiphenyl-4-acetic acid
  • Flurbiprofen EP impurity A -E
  • Flurbiprofen EP impurity A
  • [1,1'-Biphenyl]-4-acetic acid, α-methyl-
  • Flurbiprofen Impurity 1(EP Impurity A)
  • Flurbiprofen Related CoMpound A (Biprofen)
  • (2RS)-2-(Biphenyl-4-yl)propanoic acid
  • 2-(4-phenylphenyl)propanoic acid
  • 2-([1,1'-Biphenyl]-4-yl)propanoic acid
  • (R)-2-([1,1'-biphenyl]-4-yl)propanoic acid
  • 2-(4-Biphenylyl)propionic Acid
  • 2-(4-Phenylphenyl)propionic Acid
  • Flurbiprofen ImpurityⅠ:Biprofen(α-Methyl-[1,1'-biphenyl]-4-acetic Acid
  • p-Phenylhydratropic Acid
  • Flurbiprofen impurity A CRS
  • (2RS)-2-(Biphenyl-4-yl)propanoic Ac
  • Flurbiprofen Impurity 1(Flurbiprofen EP Impurity A)
  • [1,1'-Biphenyl]-4-aceticacid, a-methyl-
  • Flurbiprofen EP Impurity A (Biprofen)
  • Flurbiprofen axetil impurity1427
  • Flurbiprofen axetil impurity5
  • Flurbiprofen impurity A (F0285202)
  • Flurbiprofen Impurity Ⅰ [2-(4-Biphenylyl)propionic acid
  • Flurbiprofen USP Related Compound A
  • 2 - ([1,1 '- biphenyl] - 4-yl) propionic acid
  • Flurbiprofen EP Impurity A(Flurbiprofen Related Compound A)
  • Flurbiprofen EP Impurity A (Flurbiprofen USP Related Compound A)
  • FLURBIPROFEN EP IMPURITY A (LOT1) (LOT2)
  • Flurbiprofen-related substance A
  • 6341-72-6
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals