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alpha-Methyl-4-biphenylacetic acid

Product Name
alpha-Methyl-4-biphenylacetic acid
CAS No.
6341-72-6
Chemical Name
alpha-Methyl-4-biphenylacetic acid
Synonyms
LY-71130;p-Phenylhydratropic Acid;p-Phenylhydroatropic acid;Flurbiprofen EP impurity A;Flurbiprofen impurity A CRS;Flurbiprofen EP impurity A -E;Flurbiprofen axetil impurity5;α-Methylbiphenyl-4-acetic acid;α-Methyl-4-biphenylacetic acid;2-(4-Biphenylyl)propionic Acid
CBNumber
CB81401675
Molecular Formula
C15H14O2
Formula Weight
226.27
MOL File
6341-72-6.mol
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alpha-Methyl-4-biphenylacetic acid Property

Melting point:
168-169 °C
Boiling point:
388.3±21.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
pka
4.34±0.10(Predicted)
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Safety

RIDADR 
UN 2811 6.1 / PGIII
HS Code 
2916399000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2710
Product name
Flurbiprofen Related Compound A
Purity
PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial,certifiedrefer
Packaging
100MG
Price
$668
Updated
2024/03/01
Sigma-Aldrich
Product number
F0285202
Product name
Flurbiprofen impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
f0285202
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
BP046
Product name
2-(Biphenyl-4-yl)propionic acid
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
25MG
Price
$266
Updated
2024/03/01
Sigma-Aldrich
Product number
1285760
Product name
Flurbiprofen impurity A
Packaging
100mg
Price
$596
Updated
2024/03/01
TRC
Product number
B399050
Product name
Biprofen
Packaging
1g
Price
$1295
Updated
2021/12/16
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alpha-Methyl-4-biphenylacetic acid Chemical Properties,Usage,Production

Uses

A metabolite of Isopropylbiphenyl, a COX-2 selective inhibitor. Also an impurity of Flurbiprofen (F598700).

Synthesis Reference(s)

Synthesis, p. 456, 1982 DOI: 10.1055/s-1982-29832

alpha-Methyl-4-biphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha-Methyl-4-biphenylacetic acid Suppliers

Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
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15421
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4992
Advantage
50
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
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55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
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60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
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sales@chem-strong.com
Country
China
ProdList
17993
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Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
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021-64609160
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greensnown@163.com
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China
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9911
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
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China
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16687
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BOC Sciences
Tel
16314854226
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info@bocsci.com
Country
United States
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ShangHai Biochempartner Co.,Ltd
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17754423994 17754423994
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QQ:2853530913
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China
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Zhengzhou Acme Chemical Co., Ltd.
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0371-0371-55629727 13323845623
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2885676761@qq.com
Country
China
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6341-72-6, alpha-Methyl-4-biphenylacetic acidRelated Search:


  • alpha-Methyl-4-biphenylacetic acid
  • 2-(Biphenyl-4-yl)propanoic acid
  • LY-71130
  • p-Phenylhydroatropic acid
  • α-Methyl-4-biphenylacetic acid
  • α-Methylbiphenyl-4-acetic acid
  • Flurbiprofen EP impurity A -E
  • Flurbiprofen EP impurity A
  • [1,1'-Biphenyl]-4-acetic acid, α-methyl-
  • Flurbiprofen Impurity 1(EP Impurity A)
  • Flurbiprofen Related CoMpound A (Biprofen)
  • (2RS)-2-(Biphenyl-4-yl)propanoic acid
  • 2-(4-phenylphenyl)propanoic acid
  • 2-([1,1'-Biphenyl]-4-yl)propanoic acid
  • (R)-2-([1,1'-biphenyl]-4-yl)propanoic acid
  • 2-(4-Biphenylyl)propionic Acid
  • 2-(4-Phenylphenyl)propionic Acid
  • Flurbiprofen ImpurityⅠ:Biprofen(α-Methyl-[1,1'-biphenyl]-4-acetic Acid
  • p-Phenylhydratropic Acid
  • Flurbiprofen impurity A CRS
  • (2RS)-2-(Biphenyl-4-yl)propanoic Ac
  • Flurbiprofen Impurity 1(Flurbiprofen EP Impurity A)
  • [1,1'-Biphenyl]-4-aceticacid, a-methyl-
  • Flurbiprofen EP Impurity A (Biprofen)
  • Flurbiprofen axetil impurity1427
  • Flurbiprofen axetil impurity5
  • Flurbiprofen impurity A (F0285202)
  • Flurbiprofen Impurity Ⅰ [2-(4-Biphenylyl)propionic acid
  • Flurbiprofen USP Related Compound A
  • 2 - ([1,1 '- biphenyl] - 4-yl) propionic acid
  • Flurbiprofen EP Impurity A(Flurbiprofen Related Compound A)
  • Flurbiprofen EP Impurity A (Flurbiprofen USP Related Compound A)
  • 2-([1,1'-Biphenyl]-4-yl)propanoic acid
  • 6341-72-6
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals