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alpha-Methyl-4-biphenylacetic acid

Product Name
alpha-Methyl-4-biphenylacetic acid
CAS No.
6341-72-6
Chemical Name
alpha-Methyl-4-biphenylacetic acid
Synonyms
LY-71130;p-Phenylhydratropic Acid;p-Phenylhydroatropic acid;Flurbiprofen EP impurity A;Flurbiprofen impurity A CRS;Flurbiprofen EP impurity A -E;Flurbiprofen axetil impurity5;α-Methylbiphenyl-4-acetic acid;α-Methyl-4-biphenylacetic acid;2-(4-Biphenylyl)propionic Acid
CBNumber
CB81401675
Molecular Formula
C15H14O2
Formula Weight
226.27
MOL File
6341-72-6.mol
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alpha-Methyl-4-biphenylacetic acid Property

Melting point:
168-169 °C
Boiling point:
388.3±21.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
pka
4.34±0.10(Predicted)
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Safety

RIDADR 
UN 2811 6.1 / PGIII
HS Code 
2916399000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2710
Product name
Flurbiprofen Related Compound A
Purity
PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial,certifiedrefer
Packaging
100MG
Price
$668
Updated
2024/03/01
Sigma-Aldrich
Product number
F0285202
Product name
Flurbiprofen impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
f0285202
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
BP046
Product name
2-(Biphenyl-4-yl)propionic acid
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
25MG
Price
$266
Updated
2024/03/01
Sigma-Aldrich
Product number
1285760
Product name
Flurbiprofen impurity A
Packaging
100mg
Price
$596
Updated
2024/03/01
TRC
Product number
B399050
Product name
Biprofen
Packaging
1g
Price
$1295
Updated
2021/12/16
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alpha-Methyl-4-biphenylacetic acid Chemical Properties,Usage,Production

Uses

A metabolite of Isopropylbiphenyl, a COX-2 selective inhibitor. Also an impurity of Flurbiprofen (F598700).

Synthesis Reference(s)

Synthesis, p. 456, 1982 DOI: 10.1055/s-1982-29832

alpha-Methyl-4-biphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha-Methyl-4-biphenylacetic acid Suppliers

Canada 1 China 80 India 5 United Kingdom 1 United States 6 Global 93
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6341-72-6, alpha-Methyl-4-biphenylacetic acidRelated Search:

Flurbiprofen 2,4-Difluoronitrobenzene flurbiprofen 4-Acetyl-2-fluorobiphenyl Flurbiprofen Impurity 8 Flurbiprofen Impurity 15 2,4-Difluorobiphenyl diethyl (3-fluoro-4-nitrophenyl)methylmalonate 4'-hydroxyflurbiprofen 2-Fluorobiphenyl-4-carboxylic Acid Flurbiprofen Impurity Flurbiprofen Related Impurity 1 4-ETHYL-2-FLUORO-1,1'-BIPHENYL diethyl (4-amino-3-fluorophenyl)methylmalonate Flurbiprofen Impurity 16 (2-FLUORO-4-BIPHENYL)ACETIC ACID α-Hydroxy Flurbiprofen 2-Methylpropanedioic acid

  • alpha-Methyl-4-biphenylacetic acid
  • 2-(Biphenyl-4-yl)propanoic acid
  • LY-71130
  • p-Phenylhydroatropic acid
  • α-Methyl-4-biphenylacetic acid
  • α-Methylbiphenyl-4-acetic acid
  • Flurbiprofen EP impurity A -E
  • Flurbiprofen EP impurity A
  • [1,1'-Biphenyl]-4-acetic acid, α-methyl-
  • Flurbiprofen Impurity 1(EP Impurity A)
  • Flurbiprofen Related CoMpound A (Biprofen)
  • (2RS)-2-(Biphenyl-4-yl)propanoic acid
  • 2-(4-phenylphenyl)propanoic acid
  • 2-([1,1'-Biphenyl]-4-yl)propanoic acid
  • (R)-2-([1,1'-biphenyl]-4-yl)propanoic acid
  • 2-(4-Biphenylyl)propionic Acid
  • 2-(4-Phenylphenyl)propionic Acid
  • Flurbiprofen ImpurityⅠ:Biprofen(α-Methyl-[1,1'-biphenyl]-4-acetic Acid
  • p-Phenylhydratropic Acid
  • Flurbiprofen impurity A CRS
  • (2RS)-2-(Biphenyl-4-yl)propanoic Ac
  • Flurbiprofen Impurity 1（Flurbiprofen EP Impurity A）
  • [1,1'-Biphenyl]-4-aceticacid, a-methyl-
  • Flurbiprofen EP Impurity A (Biprofen)
  • Flurbiprofen axetil impurity1427
  • Flurbiprofen axetil impurity5
  • Flurbiprofen impurity A (F0285202)
  • Flurbiprofen Impurity Ⅰ [2-(4-Biphenylyl)propionic acid
  • Flurbiprofen USP Related Compound A
  • 2 - ([1,1 '- biphenyl] - 4-yl) propionic acid
  • Flurbiprofen EP Impurity A(Flurbiprofen Related Compound A)
  • Flurbiprofen EP Impurity A (Flurbiprofen USP Related Compound A)
  • 2-([1,1'-Biphenyl]-4-yl)propanoic acid
  • 6341-72-6
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals