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LYCOPSAMINE

Product Name
LYCOPSAMINE
CAS No.
10285-07-1
Chemical Name
LYCOPSAMINE
Synonyms
Lycopsamin;Ccris 9199;Ccirs 9199;LYCOPSAMINE;(+)-Lycopsamine Hydrochloride;(+)-Lycopsamine Discontinued, see L487545;(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(7R)-7β-hydroxy-5,6,7,7aα-tetrahydro-3H-pyrrolizine-1-yl]methyl ester;(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizine-7-yl]methyl ester;(1R-(1alpha,7(2S*,3S*),7Abeta))-(2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl 2,3-dihydroxy-2-(1-methylethyl)butanoate;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7ar)-2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S,3S)-
CBNumber
CB81411830
Molecular Formula
C15H25NO5
Formula Weight
299.36
MOL File
10285-07-1.mol
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LYCOPSAMINE Property

Melting point:
41-44°C
Boiling point:
463.3±45.0 °C(Predicted)
Density 
1.26±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C
solubility 
Chloroform, Ethanol
pka
12.59±0.29(Predicted)
form 
Solid
color 
Off-White
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89726
Product name
Lycopsamine
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$953
Updated
2023/06/20
AK Scientific
Product number
7819CA
Product name
Lycopsamine
Packaging
10mg
Price
$1062
Updated
2021/12/16
Biosynth Carbosynth
Product number
FL161608
Product name
Lycopsamine
Packaging
25mg
Price
$1600
Updated
2021/12/16
AK Scientific
Product number
7819CA
Product name
Lycopsamine
Packaging
25mg
Price
$2210
Updated
2021/12/16
Biosynth Carbosynth
Product number
FL161608
Product name
Lycopsamine
Packaging
50mg
Price
$2520
Updated
2021/12/16
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LYCOPSAMINE Chemical Properties,Usage,Production

Description

This amorphous pyrrolizidine alkaloid has been isolated from Arnsinckia hispida (Ruiz et Pav.) Johnst., A. interrnedia Fisch & Mey, and A. lycopsoides Lehm. It is dextrorotatory having [α]20D + 3.1 ° (c 5.98, EtOH). Alkaline hydrolysis yields retronecine and viridifloric acid.

Uses

(+)-Lycopsamine, occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens.It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.

Definition

ChEBI: Lycopsamine is a member of pyrrolizines.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

References

Cu1venor, Smith., Austral. 1. Chern., 19, 1955 (1966)

LYCOPSAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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LYCOPSAMINE Suppliers

China 29 France 1 Germany 1 India 2 United Kingdom 1 United States 7 Global 41
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
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58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
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80
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
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55
Biyu Biotechnology (Shanghai) Co., ltd
Tel
021-26018599
Country
China
ProdList
270
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56
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
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60

10285-07-1, LYCOPSAMINERelated Search:

PHENYLENDIAMINE Ammonium phosphate dibasic daurisoline VERATRIDINE L-Hyoscyamine Lycodoline Xanthiazone VERATRINE veratramine menisdaurin Xanthiside 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one Daurinoline ECHIMIDINE LYCOPSAMINE retronecine

  • LYCOPSAMINE
  • (2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizine-7-yl]methyl ester
  • (2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(7R)-7β-hydroxy-5,6,7,7aα-tetrahydro-3H-pyrrolizine-1-yl]methyl ester
  • (1R-(1alpha,7(2S*,3S*),7Abeta))-(2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl 2,3-dihydroxy-2-(1-methylethyl)butanoate
  • Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7ar)-2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S,3S)-
  • Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1R-(1alpha,7(2S*,3S*),7abeta))-
  • Ccirs 9199
  • Ccris 9199
  • Lycopsamin
  • (+)-Lycopsamine Discontinued, see L487545
  • (+)-Lycopsamine Hydrochloride
  • 10285-07-1
  • Amines, Heterocycles