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LYCOPSAMINE

Product Name
LYCOPSAMINE
CAS No.
10285-07-1
Chemical Name
LYCOPSAMINE
Synonyms
Lycopsamin;Ccris 9199;Ccirs 9199;LYCOPSAMINE;Lycopsamine-RM;(+)-Lycopsamine Hydrochloride;(+)-Lycopsamine Discontinued, see L487545;(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(7R)-7β-hydroxy-5,6,7,7aα-tetrahydro-3H-pyrrolizine-1-yl]methyl ester;(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizine-7-yl]methyl ester;(1R-(1alpha,7(2S*,3S*),7Abeta))-(2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl 2,3-dihydroxy-2-(1-methylethyl)butanoate
CBNumber
CB81411830
Molecular Formula
C15H25NO5
Formula Weight
299.36
MOL File
10285-07-1.mol
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LYCOPSAMINE Property

Melting point:
41-44°C
Boiling point:
463.3±45.0 °C(Predicted)
Density 
1.26±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C
solubility 
Chloroform, Ethanol
pka
12.59±0.29(Predicted)
form 
Solid
color 
Off-White
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89726
Product name
Lycopsamine
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$953
Updated
2023/06/20
AK Scientific
Product number
7819CA
Product name
Lycopsamine
Packaging
10mg
Price
$1062
Updated
2021/12/16
Biosynth Carbosynth
Product number
FL161608
Product name
Lycopsamine
Packaging
25mg
Price
$1600
Updated
2021/12/16
AK Scientific
Product number
7819CA
Product name
Lycopsamine
Packaging
25mg
Price
$2210
Updated
2021/12/16
Biosynth Carbosynth
Product number
FL161608
Product name
Lycopsamine
Packaging
50mg
Price
$2520
Updated
2021/12/16
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LYCOPSAMINE Chemical Properties,Usage,Production

Description

This amorphous pyrrolizidine alkaloid has been isolated from Arnsinckia hispida (Ruiz et Pav.) Johnst., A. interrnedia Fisch & Mey, and A. lycopsoides Lehm. It is dextrorotatory having [α]20D + 3.1 ° (c 5.98, EtOH). Alkaline hydrolysis yields retronecine and viridifloric acid.

Uses

(+)-Lycopsamine, occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens.It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.

Definition

ChEBI: Lycopsamine is a member of pyrrolizines.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

References

Cu1venor, Smith., Austral. 1. Chern., 19, 1955 (1966)

LYCOPSAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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LYCOPSAMINE Suppliers

China 32 France 1 Germany 1 India 2 United Kingdom 1 United States 7 Global 44
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10285-07-1, LYCOPSAMINERelated Search:

PHENYLENDIAMINE Ammonium phosphate dibasic daurisoline VERATRIDINE L-Hyoscyamine Lycodoline Xanthiazone VERATRINE veratramine menisdaurin Xanthiside 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one Daurinoline ECHIMIDINE LYCOPSAMINE retronecine

  • LYCOPSAMINE
  • (2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizine-7-yl]methyl ester
  • (2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(7R)-7β-hydroxy-5,6,7,7aα-tetrahydro-3H-pyrrolizine-1-yl]methyl ester
  • (1R-(1alpha,7(2S*,3S*),7Abeta))-(2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl 2,3-dihydroxy-2-(1-methylethyl)butanoate
  • Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7ar)-2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S,3S)-
  • Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1R-(1alpha,7(2S*,3S*),7abeta))-
  • Ccirs 9199
  • Ccris 9199
  • Lycopsamin
  • (+)-Lycopsamine Discontinued, see L487545
  • (+)-Lycopsamine Hydrochloride
  • Lycopsamine-RM
  • 10285-07-1
  • Amines, Heterocycles