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cilengitide

Product Name
cilengitide
CAS No.
188968-51-6
Chemical Name
cilengitide
Synonyms
D03497;CS-2674;CS-1500;EMD 12197;EMD-85189;NSC 707544;Cilengitide;C(RGDf-Me-V);c(RGDf(NMe)V);cyclo(RGDf-NMe-V)
CBNumber
CB81458790
Molecular Formula
C27H40N8O7
Formula Weight
588.66
MOL File
188968-51-6.mol
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cilengitide Property

Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
≥29.43 mg/mL in DMSO; ≥22.56 mg/mL in H2O
form 
powder
pka
4.01±0.10(Predicted)
color 
white to beige
Water Solubility 
Soluble to 10 mg/ml in water
InChIKey
AMLYAMJWYAIXIA-MAVOJUFWNA-N
SMILES
N1(C)[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC2C=CC=CC=2)C1=O |&1:2,9,24,32,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1594
Product name
Cilengitide trifluoroacetic acid salt
Purity
≥98% (HPLC)
Packaging
5MG
Price
$173
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1594
Product name
Cilengitide trifluoroacetic acid salt
Purity
≥98% (HPLC)
Packaging
25MG
Price
$662
Updated
2023/06/20
Cayman Chemical
Product number
22289
Product name
Cilengitide
Purity
≥98%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
22289
Product name
Cilengitide
Purity
≥98%
Packaging
5mg
Price
$143
Updated
2024/03/01
Cayman Chemical
Product number
22289
Product name
Cilengitide
Purity
≥98%
Packaging
10mg
Price
$223
Updated
2024/03/01
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cilengitide Chemical Properties,Usage,Production

Uses

Angiogenesis inhibitor.

Uses

Cilengitide trifluoroacetic acid salt has been used as an inhibitor of integrin αvβ5.

Definition

ChEBI: Cilengitide is an oligopeptide.

Biochem/physiol Actions

It exhibits antitumor activity in glioblastoma multiforme tumors. Integrins are heterodimers of α and β chain. They are transmembrane receptors which are responsible for cell-to-cell and cell-extracellular matrix interactions. They control tumor angiogenesis, invasion and migration.

storage

Store at -20°C

cilengitide Preparation Products And Raw materials

Raw materials

Preparation Products

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cilengitide Suppliers

China 177 China Hong Kong 1 India 4 United Kingdom 1 United States 16 Global 199
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View Lastest Price from cilengitide manufacturers

Shandong Huizhihan Supply Chain Co., Ltd
Product
Cilengitide 188968-51-6
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99%
Supply Ability
20T
Release date
2024-11-12
Shandong Huizhihan Supply Chain Co., Ltd
Product
Cilengitide 188968-51-6
Price
US $0.00-0.00/box
Min. Order
1box
Purity
99%
Supply Ability
2000
Release date
2024-10-29
American HealthyMorph LLC
Product
Cilengitide 188968-51-6
Price
US $0.00/Box
Min. Order
1Box
Purity
99%
Supply Ability
1000/week
Release date
2025-01-02

188968-51-6, cilengitideRelated Search:

Ganirelix Acetate Taltirelin Cosyntropin VAPREOTIDE Cyclooctane 1,3,5-Triazine DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* Epothilone D Isoquinoline Bortezomib Trametinib Carfilzomib LY 294002 HYDROCHLORIDE CHIR-99021 AZD-9291 Cilengitide CYCLO(ARG-GLY-ASP-D-PHE-VAL) 1,4,7,10,13-PENTAAZACYCLOPENTADECANE

  • 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
  • Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
  • Cilengitide(EMD121974,NSC-707544)
  • Cilengitide
  • C(RGDf-Me-V)
  • EMD 121974;EMD-121974;EMD121974
  • CS-1500
  • CS-2674
  • Cilengitide (EMD 121974)
  • NSC 707544
  • Cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val)
  • c(RGDf(NMe)V)
  • 2-((2S,5R,8S,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1
  • Cilengitide, >=98%
  • D03497
  • EMD 12197
  • EMD 12197;EMD-85189;EMD-121974;NSC-707544;D03497
  • EMD-85189
  • 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]aceticaci
  • cilengitide USP/EP/BP
  • 2-((2S,5R,8S,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
  • cyclo(RGDf-NMe-V)
  • Cilengitide, 10 mM in DMSO
  • 188968-51-6
  • 156-1-8
  • C27H40N8O7
  • Inhibitors