ChemicalBook > CAS DataBase List > cilengitide

cilengitide

Product Name
cilengitide
CAS No.
188968-51-6
Chemical Name
cilengitide
Synonyms
D03497;CS-2674;CS-1500;EMD 12197;EMD-85189;NSC 707544;Cilengitide;C(RGDf-Me-V);c(RGDf(NMe)V);cyclo(RGDf-NMe-V)
CBNumber
CB81458790
Molecular Formula
C27H40N8O7
Formula Weight
588.66
MOL File
188968-51-6.mol
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cilengitide Property

Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
≥29.43 mg/mL in DMSO; ≥22.56 mg/mL in H2O
form 
powder
pka
4.01±0.10(Predicted)
color 
white to beige
Water Solubility 
Soluble to 10 mg/ml in water
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1594
Product name
Cilengitide trifluoroacetic acid salt
Purity
≥98% (HPLC)
Packaging
5MG
Price
$173
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1594
Product name
Cilengitide trifluoroacetic acid salt
Purity
≥98% (HPLC)
Packaging
25MG
Price
$662
Updated
2023/06/20
Cayman Chemical
Product number
22289
Product name
Cilengitide
Purity
≥98%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
22289
Product name
Cilengitide
Purity
≥98%
Packaging
5mg
Price
$143
Updated
2024/03/01
Cayman Chemical
Product number
22289
Product name
Cilengitide
Purity
≥98%
Packaging
10mg
Price
$223
Updated
2024/03/01
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cilengitide Chemical Properties,Usage,Production

Uses

Angiogenesis inhibitor.

Uses

Cilengitide trifluoroacetic acid salt has been used as an inhibitor of integrin αvβ5.

Definition

ChEBI: Cilengitide is an oligopeptide.

Biochem/physiol Actions

It exhibits antitumor activity in glioblastoma multiforme tumors. Integrins are heterodimers of α and β chain. They are transmembrane receptors which are responsible for cell-to-cell and cell-extracellular matrix interactions. They control tumor angiogenesis, invasion and migration.

storage

Store at -20°C

cilengitide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from cilengitide manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Cilengitide 188968-51-6
Price
US $55.00-550.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-30
Henan Tengmao Chemical Technology Co. LTD
Product
cilengitide 188968-51-6
Price
US $110.00-90.00/kilogram
Min. Order
1kilogram
Purity
99%
Supply Ability
10 tons/per week
Release date
2024-03-21
Nantong Guangyuan Chemicl Co,Ltd
Product
Cilengitide 188968-51-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-16

188968-51-6, cilengitideRelated Search:


  • 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
  • Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
  • Cilengitide(EMD121974,NSC-707544)
  • Cilengitide
  • C(RGDf-Me-V)
  • EMD 121974;EMD-121974;EMD121974
  • CS-1500
  • CS-2674
  • Cilengitide (EMD 121974)
  • NSC 707544
  • Cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val)
  • c(RGDf(NMe)V)
  • 2-((2S,5R,8S,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1
  • Cilengitide, >=98%
  • D03497
  • EMD 12197
  • EMD 12197;EMD-85189;EMD-121974;NSC-707544;D03497
  • EMD-85189
  • 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]aceticaci
  • cilengitide USP/EP/BP
  • 2-((2S,5R,8S,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
  • cyclo(RGDf-NMe-V)
  • 188968-51-6
  • 156-1-8
  • C27H40N8O7
  • Inhibitors