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3-Amino-4-hydroxybenzoic acid

Product Name
3-Amino-4-hydroxybenzoic acid
CAS No.
1571-72-8
Chemical Name
3-Amino-4-hydroxybenzoic acid
Synonyms
TIMTEC-BB SBB006740;Mesalazine Impurity 12;2-amino-4-carboxyphenol;3-amino-4-hydroxybenzoate;4-HYDROXY-3-AMINOBENZOIC ACID;3-AMINO-4-HYDROXYBENZOIC ACID;BENZOIC ACID, 3-AMINO-4-HYDROXY-;3-Amino-4-hydroxybenzoic acid 97%;3-Amino-4-hydroxybenzoic acid,98%;3-AMINO-4-HYDROXYBENZOIC ACID USP
CBNumber
CB8148119
Molecular Formula
C7H7NO3
Formula Weight
153.14
MOL File
1571-72-8.mol
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3-Amino-4-hydroxybenzoic acid Property

Melting point:
208 °C (dec.) (lit.)
Boiling point:
276.03°C (rough estimate)
Density 
1.3585 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in solvents.
form 
Crystalline Powder
pka
9.06±0.18(Predicted)
color 
Beige-gray to brown
λmax
308nm(H2O (pH 11))(lit.)
Sensitive 
Light Sensitive
BRN 
972238
InChI
InChI=1S/C7H7NO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9H,8H2,(H,10,11)
InChIKey
MRBKRZAPGUCWOS-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=C(O)C(N)=C1
CAS DataBase Reference
1571-72-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
IRRITANT, AIR SENSITIVE, LIGHT SENSITIVE
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
289647
Product name
3-Amino-4-hydroxybenzoic acid
Purity
97%
Packaging
5g
Price
$48.7
Updated
2024/03/01
Sigma-Aldrich
Product number
289647
Product name
3-Amino-4-hydroxybenzoic acid
Purity
97%
Packaging
25g
Price
$92.7
Updated
2024/03/01
TCI Chemical
Product number
A0859
Product name
3-Amino-4-hydroxybenzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$113
Updated
2024/03/01
TCI Chemical
Product number
A0859
Product name
3-Amino-4-hydroxybenzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$444
Updated
2024/03/01
TRC
Product number
A634815
Product name
3-Amino-4-hydroxybenzoic acid
Packaging
100mg
Price
$60
Updated
2021/12/16
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3-Amino-4-hydroxybenzoic acid Chemical Properties,Usage,Production

Chemical Properties

beige-grey to brown crystalline powder

Uses

3-Amino-4-hydroxybenzoic acid is used to produce 4-acetoxy-3-acetylamino-benzoic acid with acetic acid anhydride at temperature of 0 - 20°C. This reaction will need reagents aq. HCl and NaOAc.

Application

3-Amino-4-hydroxybenzoic acid is the first matrix to be used specifically for carbohydrates. The other most commonly used matrices are α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, and sinapinic acid. Matrix and sample solutions are mixed prior to laser exposure, spotted on a solid metallic surface, and allowed to dry before submitting them to MALDI. These matrices are characterized by high absorptivity of the laser radiation and the capability of forming fine crystalline solids during sample/matrix drying. In general, the more fine-grained and homogeneous the morphology of crystals formed with the analyte/matrix mixture, the more intense the MALDI mass spectrum of the analyte. 3-Amino-4-hydroxybenzoic acid produced [M+Na]+ ions from as little as 1 pmol of dextran hydrolysate and N-linked glycans released from glycoproteins.

Definition

ChEBI: A monohydroxybenzoic acid that is 4-hydroxybenzoic acid carrying an additional amino substitutent at position 3.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 3740, 1989 DOI: 10.1021/jo00276a044

3-Amino-4-hydroxybenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-4-hydroxybenzoic acid Suppliers

Nanjing Thander New Material Science & Technology Co., Ltd
Tel
15384069853
Email
2048571647@qq.com
Country
China
ProdList
344
Advantage
58
Xi'an Sunriver Biotech Ltd.
Tel
15353699600
Email
info@sunriverbio.com
Country
China
ProdList
67
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58
Shanghai Fangyan Biotechnology Co., Ltd
Tel
13127575010
Email
2679388014@qq.com
Country
China
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33
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
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62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
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84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
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81
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
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sales8178@energy-chemical.com
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China
ProdList
44751
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Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
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60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
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64
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View Lastest Price from 3-Amino-4-hydroxybenzoic acid manufacturers

Nanjing jinheyou Trading Co., Ltd.
Product
3-Amino-4-hydroxybenzoic acid 1571-72-8
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
20kgs/month
Release date
2019-11-01
Nanjing jinheyou Trading Co., Ltd.
Product
3-Amino-4-hydroxybenzoic acid 1571-72-8
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
20kg/month
Release date
2019-11-04
Career Henan Chemical Co
Product
3-Amino-4-hydroxybenzoic acid 1571-72-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-08-20

1571-72-8, 3-Amino-4-hydroxybenzoic acidRelated Search:


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  • Mass Spectrometry
  • Matrix Materials (MALDI-TOF-MS)
  • Aromatic Amino Acids
  • AMINE
  • Specialty Synthesis
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Mass Spectrometry
  • Matrix Materials (MALDI-TOF-MS)
  • Analytical Chemistry
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • API intermediates
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Alcohols and Derivatives
  • Amino Acids and Derivatives
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Aromatic Amino Acids
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives