2-Boc-amino-4-formylpyridine
- Product Name
- 2-Boc-amino-4-formylpyridine
- CAS No.
- 304873-65-2
- Chemical Name
- 2-Boc-amino-4-formylpyridine
- Synonyms
- 2-Boc-amino-4-formylpyridin;2-Boc-amino-4-formylpyridine;2-(Boc-amino)pyridine-4-carboxaldehyde;tert-butyl 4-forMylpyridin-2-ylcarbaMate;tert-butyl N-(4-formyl-2-pyridyl)carbamate;(4-Formyl-pyridin-2-yl)-carbamic acid tert-butyl ester;N-(4-Formyl-2-pyridinyl)carbamic acid tert-butyl ester;2-[N,N-mono-(tert-butoxycarbonyl)amino]-pyridyl-4-aldehyde;Carbamic acid, N-(4-formyl-2-pyridinyl)-, 1,1-dimethylethyl ester
- CBNumber
- CB81501285
- Molecular Formula
- C11H14N2O3
- Formula Weight
- 222.24
- MOL File
- 304873-65-2.mol
2-Boc-amino-4-formylpyridine Property
- Melting point:
- 125-126℃
- Boiling point:
- 308.8±27.0 °C(Predicted)
- Density
- 1.212
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 12.20±0.70(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T206098
- Product name
- tert-Butyl(4-Formylpyridin-2-yl)carbamate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3201AB
- Product name
- tert-Butyl(4-formylpyridin-2-yl)carbamate
- Packaging
- 100mg
- Price
- $127
- Updated
- 2021/12/16
- Product number
- CHM0152248
- Product name
- TERT-BUTYL 4-FORMYLPYRIDIN-2-YLCARBAMATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $664.13
- Updated
- 2021/12/16
- Product number
- CHM0152248
- Product name
- TERT-BUTYL 4-FORMYLPYRIDIN-2-YLCARBAMATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1010.63
- Updated
- 2021/12/16
- Product number
- 4H51-1-4B
- Product name
- tert-Butyl (4-formylpyridin-2-yl)carbamate
- Packaging
- 1g
- Price
- $1220
- Updated
- 2021/12/16
2-Boc-amino-4-formylpyridine Chemical Properties,Usage,Production
Synthesis
304873-62-9
304873-65-2
General procedure for the synthesis of tert-butyl (4-formylpyridin-2-yl)carbamate from (4-(hydroxymethyl)pyridin-2-yl)carbamate: Synthesis of compound 2G: tert-butyl (4-formylpyridin-2-yl)carbamate Compound 2F ((tert-butyl (4-(hydroxymethyl)pyridin-2-yl)carbamate, 2.5 g, 11.15 mmol, 1.00 eq.) was dissolved in dichloroethane (DCE, 25 mL) followed by addition of manganese dioxide (MnO2, 19.4 g, 223.14 mmol, 20.02 eq.). The reaction mixture was stirred at 70 °C overnight. Upon completion of the reaction, the solid catalyst was removed by filtration. The filtrate was concentrated to dryness under reduced pressure to afford 1.4 g (57% yield) of the target product compound 2G as a white solid.
References
[1] Synthesis, 2007, # 16, p. 2529 - 2533
[2] Patent: WO2003/103669, 2003, A1. Location in patent: Page 21
[3] Patent: WO2008/108958, 2008, A2. Location in patent: Page/Page column 32
[4] Patent: WO2008/108957, 2008, A2. Location in patent: Page/Page column 30
[5] Patent: WO2018/209132, 2018, A1. Location in patent: Paragraph 0526
2-Boc-amino-4-formylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Boc-amino-4-formylpyridine Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88