5-BROMO-3-METHOXYPYRIDIN-2-AMINE

Product Name: 5-BROMO-3-METHOXYPYRIDIN-2-AMINE
CAS No.: 42409-58-5
Chemical Name: 5-BROMO-3-METHOXYPYRIDIN-2-AMINE
Synonyms: 5-BROMO-3-METHOXYPYRIDIN-2-AMINE;5-bromo-3-methoxy-2-pyridinamine;2-PyridinaMine,5-broMo-3-Methoxy-;2-Amino-3-methoxy-5-bromopyridine;2-AMINO-5-BROMO-3-METHOXYPYRIDINE;5-bromo-3-methoxypyridine-2-amine;5-BroMo-3-Methoxy-pyridin-2-ylaMine;2-Amino-5-bromo-3-methoxypyridine,96%;2-Amino-5-bromo-3-methoxypyridine 98%;5-BROMO-3-METHOXYPYRIDIN-2-AMINE ISO 9001：2015 REACH
CBNumber: CB81502732
Molecular Formula: C6H7BrN2O
Formula Weight: 203.04
MOL File: 42409-58-5.mol

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5-BROMO-3-METHOXYPYRIDIN-2-AMINE Property

Melting point:: 78-82℃
Boiling point:: 254℃
Density: 1.622
Flash point:: 107℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 5.93±0.10(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C6H7BrN2O/c1-10-5-2-4(7)3-9-6(5)8/h2-3H,1H3,(H2,8,9)
InChIKey: NFBIWMFMHLPVLT-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)C=C1OC

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Safety

HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B699645
Product name: 5-Bromo-3-methoxypyridin-2-amine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: B699645
Product name: 5-Bromo-3-methoxypyridin-2-amine
Packaging: 500mg
Price: $110
Updated: 2021/12/16

Matrix Scientific

Product number: 035155
Product name: 5-Bromo-3-methoxypyridin-2-amine
Packaging: 1g
Price: $137
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB76084
Product name: 5-Bromo-3-methoxypyridin-2-amine
Packaging: 1g
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB76084
Product name: 5-Bromo-3-methoxypyridin-2-amine
Packaging: 250mg
Price: $65
Updated: 2021/12/16

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5-BROMO-3-METHOXYPYRIDIN-2-AMINE Chemical Properties,Usage,Production

Synthesis

10201-71-5

42409-58-5

General procedure for the synthesis of 2-amino-3-methoxy-5-bromopyridine from 2-amino-3-methoxypyridine: To a 2000 mL Erlenmeyer flask was added 10% sulfuric acid solution (800 mL). 2-Amino-3-methoxypyridine (25.80 g, 206 mmol) was added at room temperature while stirring. After the solution was clarified, it was cooled to about 3°C in an ice/water bath. Subsequently, bromine (10.8 mL, 210 mmol) was slowly added to the mixture in acetic acid at 0°C. Upon completion of the reaction, the solid product was collected by filtration, washed twice (30 mL each) with cold water and dried to give 39.0 g of crude product. The crude product was suspended in ethyl acetate (500 mL) with vigorous stirring for 0.5 h and then filtered through Celite. The black solid was washed twice with ethyl acetate, and the filtrates were combined and washed sequentially with 10% sodium thiosulfate solution (100 mL) and saturated brine, and finally dried over anhydrous sodium sulfate. The mixture was concentrated to give 29.0 g (68.3% yield) of 2-amino-3-methoxy-5-bromopyridine as a yellow solid. The product was confirmed by 1H NMR (300 MHz, CDCl3): δ 7.71 (d, J = 2.1 Hz, 1H), 7.01 (d, J = 2.1 Hz, 1H), 4.69 (br s, 2H), 3.84 (s, 3H).LC-MS (m/z): 204.9 ([M+H]+).

References

[1] Patent: US2011/81316, 2011, A1. Location in patent: Page/Page column 14
[2] Patent: WO2010/96389, 2010, A1. Location in patent: Page/Page column 45-46; 48
[3] Patent: WO2010/135014, 2010, A1. Location in patent: Page/Page column 53-55
[4] Patent: WO2017/76931, 2017, A1. Location in patent: Page/Page column 20
[5] Patent: WO2010/100127, 2010, A1. Location in patent: Page/Page column 71-72

5-BROMO-3-METHOXYPYRIDIN-2-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-3-METHOXYPYRIDIN-2-AMINE Suppliers

China 94 India 2 United Kingdom 2 United States 10 Global 108

Carbosynth

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6005
Advantage: 58

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

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View Lastest Price from 5-BROMO-3-METHOXYPYRIDIN-2-AMINE manufacturers

Dideu Industries Group Limited

Product: 5-BROMO-3-METHOXYPYRIDIN-2-AMINE 42409-58-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-23

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Amino-5-Bromo-3-Methoxypyridine 42409-58-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-12

Career Henan Chemical Co

Product: 5-BROMO-3-METHOXYPYRIDIN-2-AMINE 42409-58-5
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1000KGS
Release date: 2020-01-09

42409-58-5, 5-BROMO-3-METHOXYPYRIDIN-2-AMINERelated Search:

2-Amino-5-bromo-3-methylpyridine 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine 5-BROMO-3-(1-ETHYLPROPOXY)PYRIDIN-2-AMINE 2-Amino-5-bromo-3-benzloxypyridine 7-BROMO-4-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE 5-BROMO-3-METHOXYPYRIDIN-2-AMINE METHYL 5-[3-BROMO-5-(1-ETHYLPROPOXY)-6-(METHYLAMINO)PYRIDIN-2-YL]-2,4-DIMETHOXYBENZOATE 5-BROMO-3-METHOXY-2-NITROPYRIDINE 5-BROMO-6-(2,4-DIMETHOXYPHENYL)-3-(1-ETHYLPROPOXY)-N-METHYLPYRIDIN-2-AMINE 3-BROMO-2,6-BISNITRO-5-METHOXYPYRIDINE 5-BROMO-3-(1-ETHYLPROPOXY)-6-[2-METHOXY-4-(TRIFLUOROMETHOXY)PHENYL]-N-METHYLPYRIDIN-2-AMINE 6-BROMO-3H-OXAZOLO[4,5-B]PYRIDIN-2-ONE

5-BROMO-3-METHOXYPYRIDIN-2-AMINE

2-AMINO-5-BROMO-3-METHOXYPYRIDINE

2-Amino-3-methoxy-5-bromopyridine

2-PyridinaMine,5-broMo-3-Methoxy-

5-BroMo-3-Methoxy-pyridin-2-ylaMine

5-bromo-3-methoxypyridine-2-amine

5-bromo-3-methoxy-2-pyridinamine

2-Amino-5-bromo-3-methoxypyridine 98%

2-Amino-5-bromo-3-methoxypyridine,96%

5-BROMO-3-METHOXYPYRIDIN-2-AMINE ISO 9001：2015 REACH

(1-(3-Fluoro-4-methylphenyl)-2-methylpropan-2-yl)amine

42409-58-5